propulsid

[Anonymous]

Let's review: fosamax offered to company and turned down thinking actonel is the right choice. actonel launched at wrong dose? perhaps... maybe we'll launch with flex dosing...afraid not! hip data will be the answer...afraid not! not to worry...intrinsa,stedicor, and pex showing great data....none approved!! rdp 58- wow, a great catch...wrong! asacol still bringing in the money...let's try for a 800...can't even do that right! enablex deal, having fun yet? nasal pth- do you really think there will be a market for it? Ok, we've made some bad choices, had some bad luck, but we have these great tablet pc's! Sales force concerned, unhappy..more are starting to leave. Top management says, we need to find a winner, a no doubt about it winner. The answer: propulsid
Feel better?
I'm sure the fda won't have any issues when it's up for approval, it was only pulled from the market for serious cardiac events....and I know that you koolaid drinkers are going to respond that our version will be cleaner and the fda never pulled it, it was Jannsen's decision. I hear that Merck is looking for a buyer for Vioxx..I'm not really worried...We have another year of prilosec otc!!! Also, my manager has been so helpful to me during ride-withs, I'm sure I'll only lose access to half my accounts due to the messaging I'm forced to do.

Rich and Karen will save us...the nbm is their answer...GOD HELP US ALL!

[Anonymous]

It's amazing how the company has still grown throughout all this.

My advice - leave.

[Anonymous]

original poster doesn't have to leave...aren't we entitled to better decision making from upper management and have a enjoyable experience in the field? maybe you should leave if you are happy with where we are as a pharma co.!

[Anonymous]

It's amazing how the company has still grown throughout all this.

My advice - leave.

Seriously, please explain how the pharmaceutical division has grown?

[Anonymous]

Let's review: fosamax offered to company and turned down thinking actonel is the right choice. actonel launched at wrong dose? perhaps... maybe we'll launch with flex dosing...afraid not! hip data will be the answer...afraid not! not to worry...intrinsa,stedicor, and pex showing great data....none approved!! rdp 58- wow, a great catch...wrong! asacol still bringing in the money...let's try for a 800...can't even do that right! enablex deal, having fun yet? nasal pth- do you really think there will be a market for it? Ok, we've made some bad choices, had some bad luck, but we have these great tablet pc's! Sales force concerned, unhappy..more are starting to leave. Top management says, we need to find a winner, a no doubt about it winner. The answer: propulsid
Feel better?
I'm sure the fda won't have any issues when it's up for approval, it was only pulled from the market for serious cardiac events....and I know that you koolaid drinkers are going to respond that our version will be cleaner and the fda never pulled it, it was Jannsen's decision. I hear that Merck is looking for a buyer for Vioxx..I'm not really worried...We have another year of prilosec otc!!! Also, my manager has been so helpful to me during ride-withs, I'm sure I'll only lose access to half my accounts due to the messaging I'm forced to do.

Rich and Karen will save us...the nbm is their answer...GOD HELP US ALL!

Are you looking at norcisapride? I thought Sepracor owned this.

Here's the deal with this drug: It DOES NOT work for "heartburn" for the most part. PPI's will rule here. Gastro's and nephrologists will use it for gastroparesis, possible combination with PPI for very bad "heartburn". Don't make the same mistake Janssen did by selling it as "first line" for hearburn. Sell it for those syx like "belching, bloating and regurgitation". You'll get more business that way.

It's not a bad drug, but it isn't a blockbuster. If you can PROVE it is safe, bid dose, and price it just below PPI's, you will have a peak $500 million brand.

This tells me that larger companies are looking away from blockbuster model, and are looking to capitalize on $100-500m markets to maintain revenue. This is a positive sign for our industry. It should keep us employed for a while.

[Anonymous]

initial feedback from gi's is extemely positive..there really isn't anything else like it, forced to use reglan...i'm excited about the posssiblility..just get it approved and get some strong data behind it.

[Anonymous]

original poster doesn't have to leave...aren't we entitled to better decision making from upper management and have a enjoyable experience in the field? maybe you should leave if you are happy with where we are as a pharma co.!

"entitled to...enjoyable experience in the field?" there you go again, the "entitlement" generation. work hard and achieve your goals, and if you're not doing that, don't blame "decision making from upper management". look in the mirror - you're a fucking loser and don't deserve to work here and bother the rest of us with your whining! if i were you, i'd resign and see if you can find a job at the DMV or the post office. your type usually don't want to admit your shortcomings because you got it made here - a car, salary, and all you do is get signatures and order lunches. it's always somebody else's fault. and this goes for the original poster - fuck you too.

[Anonymous]

actually, I think upper management should be held more accountable in their decision making. It's their choices that will determine if all of us have jobs 5 years from now, whether or not you made your goals! I work hard, but you have to admit, not just for us, but this job is getting worse...access issues, ethical issues. Also, how many other companies are selling drugs that are as old as ours? Docs are getting sick of the messaging we are FORCED to spew. I used to love this job but now I feel unmotivated and feel that I just go through the motions. Maybe I should leave....but it's probably worse elsewhere. I'd like to have confidence that we will survive the next few years and our recent acquisitions will pay off, but what evidence do I have that makes me think our management will get us there.

[Anonymous]

actually, I think upper management should be held more accountable in their decision making. It's their choices that will determine if all of us have jobs 5 years from now, whether or not you made your goals! I work hard, but you have to admit, not just for us, but this job is getting worse...access issues, ethical issues. Also, how many other companies are selling drugs that are as old as ours? Docs are getting sick of the messaging we are FORCED to spew. I used to love this job but now I feel unmotivated and feel that I just go through the motions. Maybe I should leave....but it's probably worse elsewhere. I'd like to have confidence that we will survive the next few years and our recent acquisitions will pay off, but what evidence do I have that makes me think our management will get us there.

it goes without saying that upper management will be held accountable if their decisions lead to failures - division closings, layoffs, etc. their decisions are only part of the equation - they need sales to make it work. if guys like you are sitting there "just going through the motions", then no business will ever succeed. and here you are asking for "evidence that makes me think our management wil get us there..." who the fuck do you think you are that PG need to show you "evidence"? who can predict the future? just read your own words - "i'd like to have confidence tht we will survive the next few years and our recent acquisitions will pay off" do the rest of us owe you something? you stay home collecting salary and benefits, and a car, and a cell phone, some lunches - is there anything else you want PG to do for you? and this from somebody "going through the motions..." fuck you and your kind. you have the nerve to post on this board.

[Anonymous]

you make it seem like I think this is the worst company in the industry, I don't! I am proud to be a part of this company, I take ownership, as a stock holder, and give them all that I have. But shouldn't management know that the MAJORITY of current reps are very unhappy, and many of the good ones are leaving because of it. Isn't it time to look to management for a new course. Can I not ask for some motivation for a sales force, anything wrong with that? I have had success with this company, but I could give a shit about the rewards. I almost rather not win, one less piece of glass to take home or another trip away from my family. I know I'm compensated very well, better than most companies would. Can't I ask for more success in getting drugs approved or make better choices for acquistions. I want this company to be the best in the industry--do you think we are heading in that direction? I think Im entitled, as a stock holder, to expect more than a 15 year old drug thats about to get the shit kicked out it...so fuck you and your kind--and this is the perfect spot to share my views--if you think you are so righteous, identify yourself!

[Anonymous]

I think everyone should calm down, I think the heat is getting to you...the stock went up 2.36 today...nobody should whine about that!

[Anonymous]

I am not saying this with the malice of the previous posters, but if you want something better from your company, you can wait for P&G to change or you can get the hell out and find what you are looking for elsewhere. Which course do you think in more likely to yield a positive result faster? There are far better companies out there. For some reason (corporate culture?) PG reps tend to hang around here hating the place, but afraid to ever do anything about it but bitch. You can make plenty of money somewhere else, let go of your addiction to the percieved "beni advantages" here and do something proactive to improve your situation.

[Anonymous]

it goes without saying that upper management will be held accountable if their decisions lead to failures - division closings, layoffs, etc. their decisions are only part of the equation - they need sales to make it work. if guys like you are sitting there "just going through the motions", then no business will ever succeed. and here you are asking for "evidence that makes me think our management wil get us there..." who the fuck do you think you are that PG need to show you "evidence"? who can predict the future? just read your own words - "i'd like to have confidence tht we will survive the next few years and our recent acquisitions will pay off" do the rest of us owe you something? you stay home collecting salary and benefits, and a car, and a cell phone, some lunches - is there anything else you want PG to do for you? and this from somebody "going through the motions..." fuck you and your kind. you have the nerve to post on this board.

"guys like you... just going through the motions?" Obviously you are a home office schill that hasn't seen the field in ages, if ever. Of course people are just going through the motions because there is no other way to survive. If you are creative, you are labeled as difficult to work with. Just going through the motions means that at least the reps are still doing their jobs! There is not much to sell right now. Old drugs, late to the the class or about to get blown out of the water by a very good rival in mmx. We are really behind the 8 ball and home office needs to quit blaming sales and look at themselves! The sales people for the most part are executing exactly what home office sends to us. FU

[Anonymous]

I think everyone should calm down, I think the heat is getting to you...the stock went up 2.36 today...nobody should whine about that!

The stock price does me no good if I don't have a job. The stock price reflects the entire company, pharma is barely a blip.

[Anonymous]

If this works, it will be huge.

[Anonymous]

Great efficacy, I was part of the launch with Janssen. Lots and Lots of contraindications. Patients called it a miracle. If P&G can clean it up, it will be a billion dollar drug.

[Anonymous]

Great efficacy, I was part of the launch with Janssen. Lots and Lots of contraindications. Patients called it a miracle. If P&G can clean it up, it will be a billion dollar drug.

How does a drug get cleaned up? The molecule has to change, and the molecule why it has great efficacy, right? Anyone know how this works, I'm genuinely interested.

[Anonymous]

Pharmacist/P&G-er speaking -- Good news is that cardiac events w/ propulsid were clearly linked to a specific component of the molecule. That part has been eliminated, and thinking is that efficacy is intact without the side effects. Only time will tell, but a very good bet -- there's nothing else out there, and nothing in range.

[Anonymous]

Pharmacist/P&G-er speaking -- Good news is that cardiac events w/ propulsid were clearly linked to a specific component of the molecule. That part has been eliminated, and thinking is that efficacy is intact without the side effects. Only time will tell, but a very good bet -- there's nothing else out there, and nothing in range.


If this is the case, then Propulsid will do VERY well. I am guessing you guys have your hands on norcisapride.

Right now, metaclopramide is the only game in town. Talk to one of your local Movement Disorder Specialists, they treat more Tardive Dyskinesia as a result of Reglan use versus any other agent, including atypicals.

Lots of need out there in GI for a prokinetic. Before you shit on your management on this one, at least see if it has QTc changes/Torsades liability first. If it does, it will be a dog. If it doesn't, you will have a winner.

[Anonymous]

Pharmacist/P&G-er speaking -- Good news is that cardiac events w/ propulsid were clearly linked to a specific component of the molecule. That part has been eliminated, and thinking is that efficacy is intact without the side effects. Only time will tell, but a very good bet -- there's nothing else out there, and nothing in range.

Cute.
Only someone from home office would have this info.
And no one from home office posts on cafepharma.
Must be the people who sold it to us trying to make themselves feel better.
If it was someone from home office, big brother is monitoring.
Hope you did it from your home computer and not your office computer.

[Anonymous]

Cute.
Only someone from home office would have this info.
And no one from home office posts on cafepharma.
Must be the people who sold it to us trying to make themselves feel better.
If it was someone from home office, big brother is monitoring.
Hope you did it from your home computer and not your office computer.

Dude, give it a rest. I am not with your organization, yet know a lot about cisapride and isomers.

So stop the conspiracy theory. All he said was that cardiac events were specific to a part of the molecule, and they feel they MAY have separated one part of the isomer from the other.

So let the data speak before you rant. Otherwise you are just illustrating your ignorance.

[Anonymous]

Forgive me if Im a little skeptical but our track record isnt exactly perfect with the FDA. If we are having issues with an 800mg Asacol I feel pretty confident propulsid wont be in our bags anytime soon.

[Anonymous]

Forgive me if Im a little skeptical but our track record isnt exactly perfect with the FDA. If we are having issues with an 800mg Asacol I feel pretty confident propulsid wont be in our bags anytime soon.

I couldn't tell you either. The FDA will certainly scrutinize a new cisapride-related molecule, given the problems Propulsid had.

But don't sell it short, it can be a winner if it is safe.

[Anonymous]

I think you are right, we had a bad track record with the FDA. The 800mg/d Asacol should have been on the market already. But, it seems that P&G always comes trough at the last minute. We might not be great at development, but we know about acquisition. Bottom line, if you worth it, the company will have your back. This is porbably one of the only pharm. companies that look at the value of the person, not just results. Some times, the territory sucks, but they know if it's you or the territory.

So, if you don't see this, people like you should NOT be here. go work for Merck or GSK, and then come back begging!

[Anonymous]

I think you are right, we had a bad track record with the FDA. The 800mg/d Asacol should have been on the market already. But, it seems that P&G always comes trough at the last minute. We might not be great at development, but we know about acquisition. Bottom line, if you worth it, the company will have your back. This is porbably one of the only pharm. companies that look at the value of the person, not just results. Some times, the territory sucks, but they know if it's you or the territory.

So, if you don't see this, people like you should NOT be here. go work for Merck or GSK, and then come back begging!

You're head is in the clouds

[Anonymous]

You're head is in the clouds

Sorry, YOUR head is in the clouds.

[Anonymous]

No, your head is in the clouds.

[Anonymous]

No, your head is in the clouds.

No, yours!!!

[Anonymous]

No, yours!!!

Actually, both of your heads are in the clouds!

[Anonymous]

Actually, both of your heads are in the clouds!

Actually, I thinks your heads are in the sand!

[Anonymous]

no, your head is in the sand

[Anonymous]

no, your head is in the sand

no, yours!