HARMONY

Wow, this will be tough,
-No cataplexy, not even in the clinical data section (this is really bad)
-No data on maintenance of wakefulness
-Decent data on ESS, but not as good as Sunosi

On the positive, it's not scheduled but I am not sure that is going to mean much

I mean this sincerely, I wish the Harmony team good luck.

 

WTH? Are main tag line is ‘non scheduled narcolepsy drug’

Who fucked up the cataplexy indication???

Fuck

 

Calm down. Cataplexy is not important.

 

Seriously? Our daytime sleepiness data is worse than providgil. I feel like I’ve been completely mislead. And management is too quiet.

 

All are jealous and should be

 

Should we be worried?
I left a good company to come here and like what I have seen but this isn’t the indication I thought we would get. My old company has already asked me back once?

 

It’s “provigil”... and I think it was inferior to provigil

 

We’re $ucked

 

You might be correct.

Wakix inferior efficacy compared to other EDS drugs, $50,000 - $100,000?, no cataplexy indication, not scheduled but label has drug interactions, QT interval prolongation, hepatic issues, reduction contraception efficacy, specialty pharmacy paperwork. Wakix on life support.

 

You Are Toast !!!!

 

All the jealous people just wait till we launch

 

All you whiners don’t deserve to be apart of this company if you can’t sell this drug then your not qualified. We hired the best of the best so some of you obviously lied during the interview. No one said pitolisant would be an easy sell which is why we only have the best. I left my comfortable cushy company for a real challenge and all of you need to man up grow a pair. When we launch you swill see how our drug is more favorable because it’s lack of scheduling. That’s all it takes to be one step ahead. It’s up to you to seal the deal. Our data is good don’t compare to other meds otherwise you’ll be distracted. Focus on our moa and the fact we are not scheduled like the other drug that doctors worry about abuse liability. The poster before me is right. All the jealous people are just talking crap.

 

Spellcheck your claim and I might have more respect for you as my competitor

 

Wakix interacts with the CYP3A4 and CPY2D6

Wakix makes birth control ineffective

Risk with Hepatic and Renal

And Harmony is not know by the sleep specialists like JAZZ

Lock the door and turn out the lights

You’re Toast !!!!

 

Add to the List

Interacts with the CYP450 3A4. And the CYP450 2D6

Makes Birth Control ineffective

Hepatic and Renal Risk Precautions

Please turn off the lights and shut the door

You’re Toast !!!!!

 

This is quite funny. Whether you work for the company or will compete against it, the drug interaction profile is minimal. All drugs for narcolepsy carry a similar warning around either birth control or teratogenicity.

QT prolongation is minimal. Nothing compared to drugs such as antipsychotics (barely moves the needle at maximum recommended dose).

Can’t give to patients with severe hepatic or patients with End Stage Renal Disease. Ok

Sucks it doesn’t have cataplexy indication at the moment. Slows the uptake but still will have a role.

 

Another jealous person and you should be, we’re the highest paid reps in the industry and just wait till we launch

 

Hate to break it to you moron, but you aren’t even in the Top 50% for compensation versus Biologics, Rare Disease, or Niche Specialty Companies

BTW - Your “stock” is also worthless because Paragon controls the rights to a move and with their current structure and losses across the board, they will not divest Harmony regardless of success or failure

You aren’t smart, you most likely weren’t in the Top 5 choices for the job you now reside in, and your ignorance couldn’t be more hysterical which is why you are in that job...until you launch and get blasted, then you will have triumphed over your ignorance with your failure

 

only a jealous and upset job seeker would spend so much time on here complaining about Harmony.