Antipsychotics/anti-epileptics increase dementia odds by 50%!

Discussion in 'Lundbeck' started by anonymous, Jun 25, 2019 at 3:56 PM.

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  1. anonymous

    anonymous Guest

    Making Patients Lives Better

    A study out of the University of Nottingham in the United Kingdom found there is a link between dementia and certain classes of anticholinergic drugs.

    The drugs — particularly antidepressants , bladder antimuscarinics, antipsychotics and antiepileptic drugs — resulted in nearly "50% increased odds of dementia," according to the observational study published Monday in the peer-reviewed JAMA Internal Medicine journal.

    Doctors prescribe these kinds of drugs to treat a variety of conditions, including chronic obstructive pulmonary disease, bladder conditions, allergies, gastrointestinal disorders and symptoms of Parkinson's disease.

    The risk is only associated with 1,095 daily doses within a 10-year period, which is equivalent to an older adult taking a strong anticholinergic medication daily for at least three years.

    Advice: Families’ best defense for dementia is early planning

    "The study is important because it strengthens a growing body of evidence showing that strong anticholinergic drugs have long term associations with dementia risk," said study author Carol Coupland, professor of medical statistics in primary care at the University of Nottingham.


    The study warns people against stopping any of the medications listed without consulting their doctors.

    More: Is there a link between hearing and dementia?

    The researchers found no significant increases in dementia risk associated with antihistamines, skeletal muscle relaxants, gastrointestinal antispasmodics, antiarrhythmics, or antimuscarinic bronchodilators, but associations were found among other classes of anticholinergic drugs.

    An estimated 47 million people worldwide were living with dementia in 2015, while in the United States around 5.7 million people have Alzheimer dementia, according to the study.
     

  2. anonymous

    anonymous Guest

    Well, I guess it’s a trade-off. Your depression/psychosis is better but you can’t remember where your pills are or when to take them! Then you are basically a a vegetable, but you are no longer hearing voices, and no longer depressed! Patients are the center of all we do! House of cards!
     
  3. anonymous

    anonymous Guest

    I’m just glad we aren’t taking about the Pacific Northwest. Dear Jesus thank you.
     
  4. anonymous

    anonymous Guest

    It’s all primary care to me.
     
  5. anonymous

    anonymous Guest

    So does reading cafepharma