Remdesivir with Brilacidin which resulted in a 99.85% Viral Load Reduction

Discussion in 'Gilead Sciences' started by anonymous, Oct 5, 2020 at 7:15 AM.

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  1. anonymous

    anonymous Guest


  2. anonymous

    anonymous Guest

  3. anonymous

    anonymous Guest

    In the RBL assay (which included Brilacidin pre-incubated with virus), Brilacidin exhibited approximately 90 percent inhibition against SARS-CoV-2 at a concentration similar to that of Remdesivir™, which again reported 50 percent inhibition of the coronavirus. The Brilacidin inhibition assay was tested in a human lung epithelial cell line, with Remdesivir™ tested in Vero cells. The RBL data also supports Brilacidin showing an ability to inhibit viral entry into cells, a highly desirable mechanism of action as it is the first step in the infection process enabling viruses to be targeted outside the cell, whereas Remdesivir™ impacts viral replication only after the host cell has been infected.

    Innovation Pharmaceuticals’ Brilacidin Inhibits Novel Coronavirus (COVID-19) by Almost 90% at the Lowest Concentration Tested to Date in a Human Lung Cell Line — Innovation Pharmaceuticals Inc.
     
  4. anonymous

    anonymous Guest

    Vitro is coming, I'm strongly expecting the stock price to explode soon. Innovation Pharmaceuticals has already announced in early October that a Pre-IND Meeting Request was granted by the FDA for the Study of Brilacidin for the Treatment of COVID-19

    "In the application, the Company has requested regulatory guidance on its planned Phase 2, randomized, double-blind, placebo-controlled, multi-center study to evaluate the efficacy and safety of Brilacidin in hospitalized patients with COVID-19. Target enrollment is 120 patients, with a planned interim analysis"

    "Extensive pre-clinical research, nearing completion, conducted at independent laboratories reinforces the antiviral potential of Brilacidin against SARS-CoV-2, the novel coronavirus responsible for COVID-19. Numerous hospitals and provider networks domestically and abroad have expressed a strong interest in participating in the Brilacidin for COVID-19 clinical trial. Given such interest in Brilacidin, the Company anticipates the planned COVID-19 trial can be rapidly recruited and completed."


     
  5. anonymous

    anonymous Guest

    Do we really need a sales force when there is already a shortage of the drug. Public opinion will not be good with the world wide pandemic.
     
  6. anonymous

    anonymous Guest

     
  7. anonymous

    anonymous Guest

     
  8. anonymous

    anonymous Guest

    Might turn into standard protocol across all hospitals. 99% is almost eradicating viral load. Cant get better than that.
    I m sure combo side effects will need to be studied before even an EU indication thus min of a year away. Likely late 2022
    Enough time for an acquisition.
     
  9. anonymous

    anonymous Guest

     
  10. anonymous

    anonymous Guest

    Gold Standard baby
     
  11. anonymous

    anonymous Guest

    VKY paid all the Hep & Onc & HQ & Dan & Joanna bonuses while VKY reps got the dry shaft