Generi Lyrica!!!! Holy Crap! Is the pain group toast??

Discussion in 'Pfizer' started by Anonymous, Jul 7, 2012 at 1:41 PM.

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  1. Anonymous

    Anonymous Guest


    Pfizer and the WSJ are not wrong in that the Lyrica patents for pain go until 2018. However, numerous links point out that the patent for epilepsy expires in Oct 2013. Too complex for some people to understand.
     

  2. Anonymous

    Anonymous Guest

    The only troll is you. You choose to defend aa wrong position by lying about the facts. Yes, you are a true public relations propaagandist from pfizer HQ. Have fun in hell when you get there.
     
  3. Anonymous

    Anonymous Guest

    Been watching w/ some amusement this back and forth for a while. Hope the dude who hates Pfizer so much finds peace on day. Is that you Peter Rost?
     
  4. Anonymous

    Anonymous Guest

    WoW - Peter Rost! what a blast from the angry past.
     
  5. Anonymous

    Anonymous Guest

    Judging from all the typos this guy is really pissed at PFE. Why all the hate? Why do you care if this drug goes generic or not?
     
  6. Anonymous

    Anonymous Guest

    Why such a dumb question? Get back to the facts and issues.

    Typos were from a crappy smart phone, btw. The hate is towards assholes. The care is because I'll lose my job likely next year instead of having lyrica to sell for 6 more years.

    Pay attention to the posts, lazy ass. How many times do we need to point this out? Go away troll.
     
  7. Anonymous

    Anonymous Guest

    http://www.prohealth.com/library/showarticle.cfm?libid=17123

    A paper published in the July 2012 issue of Arthritis & Rheumatism...
    Suggests a renewed investment interest by Pfizer Inc. in trials of its investigational drug esreboxetine as an FM therapy. (See “Safety and efficacy of esreboxetine in patients with Fibromyalgia: A 14-week, randomized, double-blind, placebo-controlled, multicenter clinical trial,” by University of Cincinnati fibromyalgia researcher Lesley M Arnold, MD, and a team at the UK-based Pfizer Global Research and Development organization.)

    For specifics not offered in the abstract of this fee-based paper...
    See MedPageToday's physician CME report (“Novel Drug Helped in Fibromyalgia”).

    By way of background, in Feb 2009...
    Pfizer announced that they were discontinuing phase 3 trials of esreboxetine after their review of existing phase 2 trial data indicated the drug was unlikely to “provide meaningful benefit to patients beyond” other fibromyalgia Rx therapies that were already FDA approved (including Pfizer’s Lyrica, aka pregabalin). The average pain score improvement in trials of the drugs had been in the neighborhood of 30% or more, about what the new Arnold, et al. paper reports.

    Now, however, at least two factors have entered the mix:

    • The big three FDA approved fibromyalgia drugs will be coming off patent starting Oct 2013 with Lyrica, opening this huge multi-billion-dollar market to competition from generally lower price generics. For example, on July 5, the FDA approved marketing of a generic pregabalin product by Lupin Pharmaceuticals. At the same time, industry analysts predict "huge market opportunities" for pharmaceutical companies owing to increased FM awareness, diagnosis rates, and market penetration.

    • And second, it is suggested that the new research reflects physician/patient experience over the past few years demonstrating that responses to/side effects of the approved drugs – and to different combinations of those drugs – differ, sometimes significantly, from patient to patient. A factor that may overcome regulatory preference for a focus on drugs to treat unmet needs.

    Currently, for example, a trial at the University of Utah is recruiting fibro patients to determine if differences in blood biomarkers can be linked to different responses to Lyrica (pregabalin) therapy.

    Each of the approved drugs - and reboxetine - involves a different mechanism of action (albeit sometimes not entirely understood).

    • Unlike the three currently approved drugs, esreboxetine is “a highly-selective norepinephrine reuptake inhibitor”: that is, it concentrates only norepinephrine in the brain.

    • Savella (milnacipran) and Cymbalta (duloxetine) concentrate both serotonin and norepinephrine, though by different means.

    • Lyrica (pregabalin) is said to decrease the release of the neurotransmitters substance P and glutamate, and “restore” release of norepinephrine.

    So overall it seems fibromyalgia and neuropathic pain patients and their physicians can expect to see continued FM drug research, by Dr. Arnold at the University of Cincinnati and others.
     
  8. Anonymous

    Anonymous Guest

    Nice find "Scoop". Guess the judge was wrong. He should have checked with ProHealth.com first before he sided w/ Pfizer in the patent case. BTW glad you just can't resist this thread. Like a moth to the flame....
     
  9. Mrs. T

    Mrs. T Guest

    I'm very disappointed to see the way you all talk to each other. I knew Lyrica could go generic sometime in the near future and googled it to see when because I cant afford it until it does. I'm very thankful for all of the hard work put into making new meds for people like me but unfortunately I will have to live with my pain until all of that hard work can be made into an affordable alternative. You are professionals and should represent yourselves as such, even when hidden by cyberspace. I can understand feeling as though you need to defend yourselves because other people are just ignorant and angry. I just ask that next time you defend yourselves without cussing and brash name calling. Thanks for all of your hard work! Keep it up, there will always be someone who cant take a med because of interactions with other meds or side affects as well as the old drugs just not working.

    For the haters... You didn't invest years of your life into an education to make meds. You didn't invest that education into years more of research and trial and error to create a new med that will help millions of people; AND YOU DON'T EXPECT TO WORK FOR FREE! Be angry with yourself insted of the people who have invested their lives into making ours better.
     
  10. Anonymous

    Anonymous Guest

    Here's the bottom line, I make $1200 a month take home and Lyrica costs $375 a month for my prescription. Somehow it seems extensively unfair. I spend more on a medicine than I do on food. The big picture is particularly askew.
     
  11. bubsleeds

    bubsleeds Guest

    ive been trying to get prescribed lyrica - pregabilin I have low mood and bad anxity no energy I tried them in prision of an inmate and I felt a 100% I know if I was on them now I would be out to work tomorrow and would get my life back with out self medicating and taking smack also in prision people were using them to cut down on methadone and get clean as it helped with withdrawals it helped me with that 2 its a great drug and should be prescribed more in uk its so hard to get prescribed things like this they don't care it changes your life for the better so why not just give it out

    do you know the benefits it has in helping come of opiates just thought I would let you know

    thanks for these drugs Pfizer
     
  12. Anonymous

    Anonymous Guest

    Yes, I've heard the same. Lyrica has proven clinical efficacy for anxiety, and it is used for aiding drug addicts to get off of their drugs.

    Not sure about the UK, because it is a commie medical system and you should get all of your drugs and treatment for free as always promised by the leftards, but here in the almost commie USA, Pfizer will give you free meds if you don't earn enough money to pay for them.

    Call 866-706-2400 for help.
     
  13. Anonymous

    Anonymous Guest

    UK has a socialist system, idiot, China is communist. Do you even care how ignorant you are?
     
  14. #54 Anonymous, Nov 21, 2013 at 6:56 PM
    Last edited by a moderator: Aug 8, 2016 at 3:46 PM
    Anonymous

    Anonymous Guest

    It's all semantics, asshole. Go ahead and try to define the differences between the two country's systems as one being socialist and the other communist. I will easily tear your annoying rude ass apart.

    The systems are all leftist and the govts control all healthcare. But go ahead and try to prove how Commies and socialists are different. Good luck, douchebag.