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  #1  
Old 07-22-2013, 04:45 PM
Anonymous
 
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Default Techfidera Death?

What do we know?
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  #2  
Old 07-22-2013, 06:11 PM
Anonymous
 
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Default Re: Techfidera Death?

Nothing to do with the drug. Pt died of an unrelated illness.
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  #3  
Old 07-23-2013, 06:37 AM
Anonymous
 
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Default Re: Techfidera Death?

That's what you assholes said about PML.
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  #4  
Old 07-23-2013, 08:37 AM
Anonymous
 
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Default Re: Techfidera Death?

Possible time line
(-) 8 weeks - PT starts bg12
(-) 7 weeks - 6 days - GI adv events begin
(-) 7 weeks - PT informed by office to "ride it out", take anti nausea and anti diarrhea meds
(-) 6 weeks through (-) 3 weeks - no relief, d/c drug + PT is now severely dehydrated
(-) 2.5 weeks - PT admitted to hospital dx - sever dehydration
(-) 2 weeks - PT acquires hospital acquired pneumonia
(-) 6 days - PT passes
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  #5  
Old 07-23-2013, 06:50 PM
Anonymous
 
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Default Re: Techfidera Death?

Welcome to the SPIN Zone!
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  #6  
Old 07-23-2013, 11:27 PM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Possible time line
(-) 8 weeks - PT starts bg12
(-) 7 weeks - 6 days - GI adv events begin
(-) 7 weeks - PT informed by office to "ride it out", take anti nausea and anti diarrhea meds
(-) 6 weeks through (-) 3 weeks - no relief, d/c drug + PT is now severely dehydrated
(-) 2.5 weeks - PT admitted to hospital dx - sever dehydration
(-) 2 weeks - PT acquires hospital acquired pneumonia
(-) 6 days - PT passes
Hospital acquired pneumonia brought about by techfidera induced diarrhea/dehydration will cause death. Oky doky!
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  #7  
Old 07-24-2013, 07:03 AM
Anonymous
 
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Default Re: Techfidera Death?

Did the patient have a low WBC count from the Tecfidera?
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  #8  
Old 07-24-2013, 03:45 PM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Did the patient have a low WBC count from the Tecfidera?
All patients will lose 30% of their white blood cell counts, they die and do not return. 4 cases of PML in Europe tied to this drug is concerning and now a death in the US that was most likely tied to it..... The Cleveland Clinic has already started doing JC Virus testing as protocol for Tecfidera and I'm sure a REMs program will be right around the corner just like Tysabri. Also the twice a day is a hassle for many patients, you can't miss a dose because of its short half life, if you do you won't be getting the full effects of the drug. The uptake of the drug has been unreal but until it's out for a few years we won't know how it will affect patients...... We don't use this drug unless they fail on other drugs, won't be a first line option for us for at least 3-5 years.
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  #9  
Old 07-24-2013, 10:00 PM
Anonymous
 
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Default Re: Techfidera Death?

great post above.
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  #10  
Old 07-25-2013, 09:03 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
All patients will lose 30% of their white blood cell counts, they die and do not return. 4 cases of PML in Europe tied to this drug is concerning and now a death in the US that was most likely tied to it..... The Cleveland Clinic has already started doing JC Virus testing as protocol for Tecfidera and I'm sure a REMs program will be right around the corner just like Tysabri. Also the twice a day is a hassle for many patients, you can't miss a dose because of its short half life, if you do you won't be getting the full effects of the drug. The uptake of the drug has been unreal but until it's out for a few years we won't know how it will affect patients...... We don't use this drug unless they fail on other drugs, won't be a first line option for us for at least 3-5 years.
Wouldn't it be nice if a drug company bothered to test this BEFORE it got to the stage of causing PML and killing people!! Woops...sorry, a little collateral damage can't get in the way of profit!
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  #11  
Old 07-25-2013, 11:56 AM
Anonymous
 
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Default Re: Techfidera Death?

Just another phony scandal. Move along!
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  #12  
Old 07-26-2013, 08:25 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Just another phony scandal. Move along!
Wasn't that what Biogen said about PML and Tysabri when it first was announced...then the execs sold their stock and made millions after delaying the info for 2 weeks. Don't you just love these people who say they are so interested in the health of MS patients!!!
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  #13  
Old 07-26-2013, 04:47 PM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
All patients will lose 30% of their white blood cell counts, they die and do not return. 4 cases of PML in Europe tied to this drug is concerning and now a death in the US that was most likely tied to it..... The Cleveland Clinic has already started doing JC Virus testing as protocol for Tecfidera and I'm sure a REMs program will be right around the corner just like Tysabri. Also the twice a day is a hassle for many patients, you can't miss a dose because of its short half life, if you do you won't be getting the full effects of the drug. The uptake of the drug has been unreal but until it's out for a few years we won't know how it will affect patients...... We don't use this drug unless they fail on other drugs, won't be a first line option for us for at least 3-5 years.
The Cleveland Clinic 's protocol is to JCV test prior to all DMT's, not a specific protocol to Tysabri & Tecfidera.
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  #14  
Old 07-26-2013, 11:55 PM
Anonymous
 
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Default Re: Techfidera Death?

The fast uptake for tecfidera is based on all the bought neurology biogen loyalists converting pts over from avonex....is that really shocking to anyone who has sold against the BI machine the last 5 yrs? C'mon....lets see what % RXs are from these BI loyalist offices.
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  #15  
Old 07-27-2013, 07:04 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
The fast uptake for tecfidera is based on all the bought neurology biogen loyalists converting pts over from avonex....is that really shocking to anyone who has sold against the BI machine the last 5 yrs? C'mon....lets see what % RXs are from these BI loyalist offices.
Oh I can't wait for that ims data to show majority is from copaxone. They and Gilenya are finished.

Did I say FINISHED loud enough for you to here me in Kansas and NJ?
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  #16  
Old 07-27-2013, 11:12 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Oh I can't wait for that ims data to show majority is from copaxone. They and Gilenya are finished.

Did I say FINISHED loud enough for you to here me in Kansas and NJ?
Isn't this nice to see for an MS patient...the drug companies who make these medications that we pay thousands of dollars for gloating against one another as to who is going to make the most profit. What a wonderful level of concern for MS patients!!
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  #17  
Old 07-28-2013, 10:17 PM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Isn't this nice to see for an MS patient...the drug companies who make these medications that we pay thousands of dollars for gloating against one another as to who is going to make the most profit. What a wonderful level of concern for MS patients!!
It's about money not patients
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  #18  
Old 07-29-2013, 09:25 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
It's about money not patients
That's what makes me sick when the Biogen marketing/sales people make all those wonderful press releases telling us how they are so interested in the health and well being of MS patients!!! Puke!
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  #19  
Old 07-29-2013, 10:15 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Oh I can't wait for that ims data to show majority is from copaxone. They and Gilenya are finished.

Did I say FINISHED loud enough for you to here me in Kansas and NJ?


I saw the same post during Tysabri launch then PML. Just wait Techfidera will have PML just a matter of time. Biogen is the PML company you are cursed
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  #20  
Old 07-30-2013, 12:54 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Isn't this nice to see for an MS patient...the drug companies who make these medications that we pay thousands of dollars for gloating against one another as to who is going to make the most profit. What a wonderful level of concern for MS patients!!
Loud enough??? not sure, but your straining must have caused some shit to leak into your panties because it sure smells. hey wait a minute....are you taking tec???
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  #21  
Old 07-30-2013, 08:27 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Loud enough??? not sure, but your straining must have caused some shit to leak into your panties because it sure smells. hey wait a minute....are you taking tec???
Why am I not surprised at all to read this kind of comment from someone who is so concerned about the health of MS patients?
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  #22  
Old 07-30-2013, 08:28 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
I saw the same post during Tysabri launch then PML. Just wait Techfidera will have PML just a matter of time. Biogen is the PML company you are cursed
Not for nothing but you trolls post all this CRAP...there's probably not even 1 Biogen employee who posts any of this garbage. Kind of funny how tecfidera is spelled WRONG on every post. You morons from Novartis need to learn how to spell when you imposter a Biogen employee.

Google it, I'm sure they can help you with your grammar.

Idiots
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  #23  
Old 07-30-2013, 12:56 PM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Not for nothing but you trolls post all this CRAP...there's probably not even 1 Biogen employee who posts any of this garbage.
Oh pleeaaassseee....what are you sniffing today??
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  #24  
Old 07-31-2013, 12:51 AM
Anonymous
 
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Default Re: Techfidera Death?

Fumarate
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  #25  
Old 08-15-2013, 08:31 PM
Anonymous
 
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Default Re: Techfidera Death?

Rumors of number 2 surfacing..facts please!
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  #26  
Old 08-15-2013, 08:37 PM
Anonymous
 
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Default Re: Techfidera Death?

Rumors of number 2 surfacing..facts please!
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  #27  
Old 11-04-2013, 01:25 AM
Anonymous
 
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Default Re: Possible Tecfidera Dural Leak/Tear in the neck

Hi, I would just like to add my little experience. Had been on rebif for just over a year. No real change but started to get needle fatigue. Here's the timeline. Stopped my rebif Sun Sept 22. Started Tecfidera Mon Sept 23, single dose M/N. Jump to double dose the following week. Started getting a weird headache that Tuesday Sept 1sr of that week. Stopped tecfidera in the meantime and went to Emerge Thurs Sept 3 and over to Sept 5. Ran tests which incl CT/MRI brain. Docs said all was clear that it must be just a stubborn headache, gave some meds, if it gets worse go to Fam Phy. Headache seem to let up slightly so I continued Tecfidera later that week at single dose (Think it was Thurs Oct 10). Stayed at single does till the following and stopped again (Think it was Thurs Ocr 17). Headache seem to still be there but was getting worse oddly. Went through the weekend in bed barely moving called the fam phy on Tues Oct 22, got me in that day. Gave me some pain meds and talked about possible sinus infection and to call him on Thurs Oct 24 if it was still bad. Still bad, called and he sent sinus antibiotics and said thar if it did not clear by the weekend go to Emerge. So guess what, it didnt clear. So Sat Oct 26 back to emerge, doc reviewed scans from Oct 5 said it looked like there was low cranial pressure. In hospital till Nov 1. Ended up doing a full back MRI, showed there was a CSF dural leak/tear in my upper neck.. Told it should heal on its own as a blood patch probably won't make it that high. Feeling better, just kinda pissed it was missed early Oct and ended up getting worse. Main symptom was Frontal postual pressure head pain. Headache only standing or sitting. Lying down was instant relief. In those other position, the pressure and pain in my forehead and behind eyes was so bad I wanted to stab knitting needles through my eyes. Pain was caused from the leak which did not allow the brain to float properly and pressed against pain signals. Check online for specific details. Freak occurance or is?? it?
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  #28  
Old 11-04-2013, 07:04 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
Rumors of number 2 surfacing..facts please!
True. Reported to biogen but haven't heard anything. Typical.
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  #29  
Old 11-06-2013, 06:02 PM
Anonymous
 
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Default Re: Techfidera Death?

my husband started this techfidera after 3 weeks got out of no where- he got deathly sick diarea throwing up weak,black stools- went to dr oh you must have food poison or flu keep taking techfidera
so he had stopped for week- so sick then started again on one pill gets hives on face ,weak
diarea and now he has to take 2 aday .........he already has the virus in him thats why he cant take the other one tysabri any more he was on tysabri 2 years before they took him off he was then told now they test for virus after he had already taken it for years...so now im reading this stuff do we stop or continue techfiedea he has been on every thing ...............
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  #30  
Old 11-08-2013, 10:27 PM
Anonymous MS Patient
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
my husband started this techfidera after 3 weeks got out of no where- he got deathly sick diarea throwing up weak,black stools- went to dr oh you must have food poison or flu keep taking techfidera
so he had stopped for week- so sick then started again on one pill gets hives on face ,weak
diarea and now he has to take 2 aday .........he already has the virus in him thats why he cant take the other one tysabri any more he was on tysabri 2 years before they took him off he was then told now they test for virus after he had already taken it for years...so now im reading this stuff do we stop or continue techfiedea he has been on every thing ...............
My advice would be to just stop. Do nothing for now. Let his system recover. Then re-evaluate. Is his MS really that bad to the point where it is worth risking his life with any of these potentially deadly monoclonal antibody drugs?
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  #31  
Old 11-11-2013, 02:37 AM
Anonymous
 
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Default Re: Techfidera Death?

I'm still off. Headaches are getting better so I'LL think my leak is healing. Have appt end of Nov to figure what the next step. Who knows if tecfidera was the cause.. Hope to ger some answers soon...
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  #32  
Old 11-12-2013, 09:22 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
I'm still off. Headaches are getting better so I'LL think my leak is healing. Have appt end of Nov to figure what the next step. Who knows if tecfidera was the cause.. Hope to ger some answers soon...
Good luck! It's not for everyone and thankfully there are other options!!
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  #33  
Old 12-03-2013, 10:41 PM
Anonymous
 
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Default Re: Techfidera Death?

If you feel like crap on Tecfidera then just stop it. Don't continue because your neurologist who happens to be bought by Biogen tells you to stay on it. All the neurologists who used Tysabri are now using Tecfidera and getting honorariums for their consultant feedback about how great it is working on their pts. Go back on Rebif, so what if you have to poke yourself a few times a week at least your not going to have some weird side effect and irreversible DMV to your brain.
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  #34  
Old 12-06-2013, 08:20 PM
Anonymous
 
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Default Re: Techfidera Death?

For those of you posting this crap about Biogen not caring about the MS patients etc.. I work at Biogen and my mother is on one of our drugs for MS. I have worked at several Biotech companies that I would'nt take one thing they made, yet I feel so comfortable with Biogen and their MFG process that my own mother takes one of the drugs... go post your lies on your own board... trying to scare people wont work!
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  #35  
Old 12-07-2013, 09:37 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
For those of you posting this crap about Biogen not caring about the MS patients etc.. I work at Biogen and my mother is on one of our drugs for MS. I have worked at several Biotech companies that I would'nt take one thing they made, yet I feel so comfortable with Biogen and their MFG process that my own mother takes one of the drugs... go post your lies on your own board... trying to scare people wont work!
Please wait while I get a kleenex to wipe the tears away!! We don't have to try and scare people...Biogen does a pretty good job of that with selling their drugs that have horrible side effects...and then telling everyone how safe they are.

Nice spin though...you guys are the absolute best at that...remember when you told the world how safe Tysabri was to take??!! Your execs made millions on that one...but of course that isn't considered a lie by Biogen!
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  #36  
Old 12-07-2013, 05:57 PM
Anonymous MS Patient
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
For those of you posting this crap about Biogen not caring about the MS patients etc.. I work at Biogen and my mother is on one of our drugs for MS. I have worked at several Biotech companies that I would'nt take one thing they made, yet I feel so comfortable with Biogen and their MFG process that my own mother takes one of the drugs... go post your lies on your own board... trying to scare people wont work!
Hopefully it's Avonex which won't kill here. Otherwise, I assume you've made sure you are going to be well taken care of in her Will when she dies.
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  #37  
Old 12-10-2013, 10:17 PM
Anonymous
 
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Default Re: Techfidera Death?

What a great way to save costs from a company that isn't getting the expected revenue from Tysabri. Nice to know that Buyogen is so concerned about the health of MS patients!!!!

http://www.ms-uk.org/MSnews
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  #38  
Old 12-11-2013, 02:13 AM
Anonymous MS Patient
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous View Post
What a great way to save costs from a company that isn't getting the expected revenue from Tysabri. Nice to know that Buyogen is so concerned about the health of MS patients!!!!

http://www.ms-uk.org/MSnews
Tysabri is extremely effective in rats. No surprise they're running (or hobbling) around Biogen facilities!

I even read in the DailyMail.co.uk yesterday that Vitamin B is more effective than any of the killer drugs! Now that was funny! Where do I go to get stung by bees? Count me in! <snicker>
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  #39  
Old 12-14-2013, 10:24 AM
Anonymous
 
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Default Re: Techfidera Death?

Quote:
Originally Posted by Anonymous MS Patient View Post
Tysabri is extremely effective in rats. No surprise they're running (or hobbling) around Biogen facilities!

I even read in the DailyMail.co.uk yesterday that Vitamin B is more effective than any of the killer drugs! Now that was funny! Where do I go to get stung by bees? Count me in! <snicker>
I guess things like Vitamin B and bees don't end up turning your brain to jello like Kilsabri does!!!
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