If you sell now consider if you have had long term gains for the tax benefits. (These would be from the 2011 ESPP offering.) Last years shares would be short term hold so you pay a greater tax. Either way a nice profit if you sell now to lock in some gains.
It was nice of you to give an actual answer. I was ready to read some really mean ones. The OP should think about talking to an adviser though. Cafepharma is the last place to look to for $$ tips.
What about those who elected to choose Shire stock as an option in their 401k plan? What will happen to those shares?