Cosentyx

Discussion in 'Novartis' started by Anonymous, Oct 20, 2014 at 3:33 PM.

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  1. Anonymous

    Anonymous Guest

    6 deaths
    29.3% infections
    18.6% URTIs
    3.55 Candida infections
    0.51% MACE
    6.54% CCV Related Events
    1.49% MALIGNANT TUMORS
    4.5% hypersensitivity
    1.37% NEUTROPENIA
    0.18% Crohns
    1.6%HERPES INFECTIONS
    12.2% of infections required antimicrobial treatment
    AUTOIMMUNITY
    IMMUNOGENICITY


    Looks like that efficacy comes with a price
     

  2. Anonymous

    Anonymous Guest

    If you view the FDA briefing documents or read the NEJM manuscript the facts are that the incidence of adverse events are similar to etanercept. Both have a higher incidence of AEs than placebo. But the numbers you are quoting are absolute values and you need to consider that even placebo treatment (standard of care) results in AEs.

    The advisory committee today voted unanimously that the efficacy benefits outweighed the safety risk.

    I am not a Novartis homer defending the company but you should be familiar with facts and have dome perspective before you try to discredit what is clearly a very impressive outcome from an FDA advisory meeting. While the serelaxin FDA meeting was clearly an epic failure, today's result is a resounding victory.
     
  3. Anonymous

    Anonymous Guest

    First Celgene rejected me for a job selling their dog.

    Now, you rejected me for selling this fungal growing half a biologic.

    Let me tell you, I will not stand for it.

    We have better managed care coverage than anyone, including Enbrel. We own skin. We are now beating Enbrel in joints. We own all GI indications.

    I will crush you. You had a chance to hire the biologics pro and you passed.

    I have crushed Celgene and I will crush you.
     
  4. Anonymous

    Anonymous Guest

    FU!
     
  5. Anonymous

    Anonymous Guest

    Well said. Additionally, what the angry little person fails to mention and/or accept, is the fact that patients who have diseases that compromise their immune system are at an increased risk for a wide variety of illnesses just because of their disorder.
     
  6. Anonymous

    Anonymous Guest

    Has anyone seen pricing information?
     
  7. Anonymous

    Anonymous Guest

    Anyone seen a specialty pharmacy list for Cosentyx distribution?
     
  8. Anonymous

    Anonymous Guest

    Heard from our Trade guys that Accredo will not stock or distribute us. That sucks.
     
  9. Anonymous

    Anonymous Guest

    Enbrel is safer. Enbrel is the gold standard. This drug's safety profile is yet to be seen. This drug did not crush Enbrel.
     
  10. Anonymous

    Anonymous Guest

    3rd line at best
     
  11. Anonymous

    Anonymous Guest

    Consumer here. I have been looking into a biologic but am very hestitant mainly because of the adverse events and the price tag. My derm has told me I can try a sample of Enbrel if i so chose, and i was wondering if you know if I will be able to sample Secukinumab?
     
  12. Anonymous

    Anonymous Guest

    Dear Consumer: Just a head's up, but this site is 99% despondent, burnt out reps that have nothing else to do but post mean, cruel things anonymously. I wouldn't spend much time on this site looking for valuable information. This is more for the entertainment of one rep telling another rep or manager to f#ck off etc.

    A quick answer to your question, however, is no samples.

    Good luck.
     
  13. Anonymous

    Anonymous Guest

    Why would you want to inject yourself twice at separate sites to get a complete dose?
     
  14. Anonymous

    Anonymous Guest

    because the 300mg is $75k
     
  15. Anonymous

    Anonymous Guest

    Hmmm…I don't know. But if that's the best you can do, I'm feeling good about the launch.
     
  16. Anonymous

    Anonymous Guest

    Any one can launch and attempt to sell "crap"! Wide use and HCP/payer acceptance is a different matter.
     
  17. Anonymous

    Anonymous Guest

    Immune suppression, infections, and cancer; it's made by Novartis.
     
  18. Anonymous

    Anonymous Guest

    you will feel the wrath

    first Celgene didn't hire me

    then you didn't even call me back

    i am a biologics pro! a pro!

    you can't sell a biologic with cream reps who look good and know how to party

    I will crush you. I will absolutely kill your product.

    ask Celgene. I buried them.

    before that, I buried Stelara.

    Before that, I took Enbrel's leading share.

    I will crush NVS. like a bug.

    you should have hired a pro instead of a bunch of hot women
     
  19. Anonymous

    Anonymous Guest


    Let it go loser, let it go.
     
  20. Anonymous

    Anonymous Guest

    Again, you've got nothing on payer acceptance. This is going to be easier than I thought.