Top-Line Results Announced of Pivotal Phase 3 Motesanib Trial in Advanced Non-Squamou

Discussion in 'Amgen' started by Anonymous, Mar 30, 2011 at 3:56 PM.

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  1. Anonymous

    Anonymous Guest

    http://www.prnewswire.com/news-releases/top-line-results-announced-of-pivotal-phase-3-motesanib-trial-in-advanced-non-squamous-non-small-cell-lung-cancer-patients-118901699.html

    Amgen (Nasdaq: AMGN), Millennium: The Takeda Oncology Company, and Takeda Pharmaceutical Company Limited (TSE: 4502) today announced top-line results from the MONET1 pivotal Phase 3 trial evaluating motesanib administered in combination with paclitaxel and carboplatin in 1,090 patients with advanced non-squamous non-small cell lung cancer (NSCLC). The trial did not meet its primary objective of demonstrating an improvement in overall survival (OS) (hazard ratio 0.90, 95 percent CI 0.78 – 1.04, p=0.14).

    "We are disappointed with the results from this trial, but look forward to further analysis of the data which may ultimately help inform future research in this area," said Roger M. Perlmutter, M.D., Ph.D., executive vice president of Research and Development at Amgen.
     

  2. Anonymous

    Anonymous Guest

    Re: Top-Line Results Announced of Pivotal Phase 3 Motesanib Trial in Advanced Non-Squ

    And the pipeline grows smaller by 1. Now tell me again. Why do Kevin and Roger get such large bonuses and paychecks?
     
  3. Anonymous

    Anonymous Guest

    Re: Top-Line Results Announced of Pivotal Phase 3 Motesanib Trial in Advanced Non-Squ

    KS and the boys are great...sell a dog of a drug to Takeda, let them spend the development money and Amgen still walks aways with millions. Amgen knew it was a dog from the beginning. Not a good way of treating a partner. What other molecules did Amgen sell off that are worthless???
     
  4. Anonymous

    Anonymous Guest

    Re: Top-Line Results Announced of Pivotal Phase 3 Motesanib Trial in Advanced Non-Squ

    The only thing I am concerned with is, a nice dividend announcement at the upcoming 4-20-11, 1/4 report, and maybe, even more exciting news at the investment meeting being held the next day.

    Prayer meeting will be held the night before and substitutes the regular Bible meeting. The theme will be " money, mo money, mo money"!