The Truth about costs to bring a drug to market

Discussion in 'Merck' started by Anonymous, May 20, 2014 at 11:25 AM.

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  1. Anonymous

    Anonymous Guest

    http://www.aarp.org/health/drugs-supplements/info-2014/rising-cost-of-cancer-drugs.html


    Inflated costs

    The most famous industry-sponsored estimate claims that it costs on average $1.3 billion to develop a new drug and get it approved. This includes the cost of failures. Half that estimate, however, is not research cost at all, but rather a high figure for profits that companies would have made if they had invested their research money in stocks and bonds instead. Profits forgone is a common way of estimating whether it's worthwhile to undertake a new project. But it is not a real cost that must be recouped from customers. Eliminating it brings the actual research costs down from $1.3 billion to $650 million.

    In addition, taxpayers subsidize about half of company research costs through credits and deductions granted to drug companies. This brings companies' real research costs down to $325 million.

    Moreover, the industry's $1.3 billion is based on a sample of the most costly fifth of new drugs, not the average for all drugs. Correcting this distortion brings company research costs down by 30 percent, to $230 million. Also, a few expensive projects always inflate the overall average, so it's more accurate to use the median cost — the point at which half of the research projects cost more and half less. This brings company research costs down to $170 million. Further, clinical trials in cancer are smaller and shorter than trials for other diseases, so trial costs should be smaller, too.

    A final way in which research costs are inflated is by backing in a large estimate for the cost of basic research to discover new drugs. In fact, no accurate estimate exists because the costs of discovery vary so much, from an inexpensive lucky break to a costly 30-year search before a new drug is discovered. Removing that inflated estimate for basic research costs brings the net, median corporate research costs down to just $125 million for developing drugs.

















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