Problem with PD1! Will not get approval!!

Mark Shenebaum of ISG is known to favor Merck over BMS. This is HIS Opinion, that's it. He knows nothing, just a wishful thinking on his part that makes him spread rumors.

 

The truth will come out by June and then the layoffs will start in August. There is a simple reason that our MSLs are not as excited about this drug as they were with Yervoy, they already know the safety profile is going to hurt us. Think back to how much they were doing pre launch af Yervoy. Compare that to what they are currently doing.....any questions?

 

You are right on! Problems with the drug.

 

I heard there was liver toxicity seen in the first trial and that they quickly decided to start a new trial to see if this is a fluke or a major problem. I hope it's not an issue but my source was pretty confident that it is an issue. I was really pumped after the POA, now I feel deflated a bit.

 

So which of the 30+ trails completed or running were a problem? Yeah, the company is worried that the drug is going no where.

 

Why don't you smoke us?

 

I might get lung cancer and unfortunately it doesn't look like your PD1 will be out any time soon to help me. Why don't you smoke us? What a loser! I was merely letting you know what I heard. The fact is that there was an issue with a study and it will be a while before coming to market. Fall earliest. There are plenty of studies to be done that will answer if the issue is an anomaly or not. Regardless, it appears as if Merck will be first to get a shot at approval. Notice I didn't say get approval. I'm sure they'll screw it up. They don't have the best track record with the FDA.

 

Well another accurate prediction on Cafepharma.

LOL

 

What an achievement! When this program started we were ahead of Merck by at least 6-12 months. Look where we ended-up. it took us 11 years to bring Yervoy to market. It took Roche 3 years to do that with Zelboraf.

 

Really. And you would rather be in the melanoma market with Merck or Genentech ? Plus future indications within those product lines? Really? Just a dumb post.

 

Wonderful drug for patients, applaud BMS to bring to market in an unprecedented timeline!! Worked with team for years, unfortunately they left a few 'bodies' in the road getting there. And still targeting.