What does competition have to do with Natpara not being in Rare Disease? Natpara team will have challenges, but competition isn't one of them... and Natpara is a long way from being a GI/IM drug.
Good luck finding qualified natpara reps. Successful rare disease reps won't want any part of this and the ones that signed on before shire are going to run for the hills. Much different sell compared to IM/GI.