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  #1  
Old 05-04-2009, 06:09 PM
Anonymous
 
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Default Savella

A funny and sobering post from the Forest board today:


"Today is the day...the official launch day with samples...yippee. So my biggest questions will be these...how many docs are going to say or get a call saying...1-never heard of it. 2-don't treat FM 3-not in stock at phcy 4- not coveraged on MC plan- too expensive 5-pt wants a generic drug 6-this drug interacts with others pt is on. Oh the joys of launching a drug in an all ready existing class...snri's....wait...we have done this b/4...we can do it...we are Forest Reps"......
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  #2  
Old 05-04-2009, 07:14 PM
Anonymous
 
Posts: n/a
Angry Re: Savella

Not to beat a dead horse...BUT...who agreed to have Rheums be DX-only? What a waste of Cypress reps talents. We have the time going over Avise, yet our hands are tied with these docs even if they ask about Savella-we can't get credit for their rx's so, why discuss it or leave samples. I can see how this will play out...big office of 5 Rheums only 3 are rx/dx...but wait, I get scripts from the 2 dx only drs. How sad for me....I don't get credit for them!!!!
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  #3  
Old 05-04-2009, 07:37 PM
Anonymous
 
Posts: n/a
Default Re: Savella

thats nothin, how bout the Primary Care offices or Orthopods that have 10-15 in the practice and only 1 is on your "target list"? Talk about waste of time and effort. At least you have a few RHUEM who you can roll the dice with, and get a credit based signature and call credit from! Many territories have large portions of PC, AN, GP, IM.....a call panel like that, you would be lucky to ever see you 1 target hidden in the pile............impossible situation.
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  #4  
Old 05-05-2009, 08:01 AM
Anonymous
 
Posts: n/a
Default Re: Savella

And how about the many sample lock-outs that are already occurring because the Forest reps share every single one of our targets. First day of the launch, and in several different offices I was told "someone was just here with that...." It's truly pathetic. Talk about a salesforce being set up to fail!
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  #5  
Old 05-05-2009, 05:35 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Busting our asses with Forest-deleted call-deck loser docs- for a target payout of $6,250???

What the hell?? This misery is SO not worth it-the way, don't forget to get some new Dx

accounts too- in your spare time!

All you people looking for jobs, step right up- you're welcome to it. I'd be happier with

unemployment.
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  #6  
Old 05-06-2009, 03:25 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Busting our asses with Forest-deleted call-deck loser docs- for a target payout of $6,250???

What the hell?? This misery is SO not worth it-the way, don't forget to get some new Dx

accounts too- in your spare time!

All you people looking for jobs, step right up- you're welcome to it. I'd be happier with

unemployment.
go cry elsewhere baby cheeseface we need winners here!
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  #7  
Old 05-06-2009, 05:21 PM
Anonymous
 
Posts: n/a
Default Re: Savella

ha, winners? puleeez daddy fuckface......you would be hard pressed to find a "winner" here at old Cypress......most were desperately seeking a paycheck and had to take the only offer on the table....they know this and knew this...the market is starting to pick back up, the good reps will be gone in a blink. This is no place for winners, wake up you phoney.
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  #8  
Old 05-06-2009, 08:35 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
ha, winners? puleeez daddy fuckface......you would be hard pressed to find a "winner" here at old Cypress......most were desperately seeking a paycheck and had to take the only offer on the table....they know this and knew this...the market is starting to pick back up, the good reps will be gone in a blink. This is no place for winners, wake up you phoney.
gp eat your generic fruit loops-there in bags =save your cheeksa nickel
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  #9  
Old 05-06-2009, 08:51 PM
Anonymous
 
Posts: n/a
Arms Re: Savella

Quote:
Originally Posted by Anonymous View Post
thats nothin, how bout the Primary Care offices or Orthopods that have 10-15 in the practice and only 1 is on your "target list"? Talk about waste of time and effort. At least you have a few RHUEM who you can roll the dice with, and get a credit based signature and call credit from! Many territories have large portions of PC, AN, GP, IM.....a call panel like that, you would be lucky to ever see you 1 target hidden in the pile............impossible situation.
spine docs, who only do surgery and fusion for slipped or dislocated discs cannot understand why we are calling on them? they don't write cymbalta, maybe a litle lyrica if they can get a pre authorization. spine docs think it is unproductive to call on them.
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  #10  
Old 05-06-2009, 09:30 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Spine docs? What are you doing call on Spine Specialists? Savella is a CNS drug, Fibro is a CNS disorder, of course a spine doc or ortho would laugh you out of the office, hello?????? They cut and inject, the last thing they want to see walk in is some wacko claiming to suffer from fibro, they want to get those patients out as soon as possible.....get them back to the Psychiatrist!!!!!!!!!!
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  #11  
Old 05-06-2009, 09:40 PM
Anonymous
 
Posts: n/a
Default Re: Savella

of course spine docs don't want to see us- that's the crap we were given to call on. We have all of the docs that forest cut out of their call panels. All just to get a few measly scripts they might occasionally write so we can get 9 calls a day so cypress gets their big , fat payment.

Why do you think we're getting paid per target instead of zip or universe. These targets will barely write anything!!! While we make nothing- management gets even richer!! NICE.... No wonder everyone hates working at this company.
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  #12  
Old 05-06-2009, 09:44 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Spine docs? What are you doing call on Spine Specialists? Savella is a CNS drug, Fibro is a CNS disorder, of course a spine doc or ortho would laugh you out of the office, hello?????? They cut and inject, the last thing they want to see walk in is some wacko claiming to suffer from fibro, they want to get those patients out as soon as possible.....get them back to the Psychiatrist!!!!!!!!!!


Very True! Great post. Notice we did not talk about any of that at the meetings, and I have never heard a manager bring this up, even though it is so freaking obvious!
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  #13  
Old 05-06-2009, 10:34 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
of course spine docs don't want to see us- that's the crap we were given to call on. We have all of the docs that forest cut out of their call panels. All just to get a few measly scripts they might occasionally write so we can get 9 calls a day so cypress gets their big , fat payment.

Why do you think we're getting paid per target instead of zip or universe. These targets will barely write anything!!! While we make nothing- management gets even richer!! NICE.... No wonder everyone hates working at this company.

Wow, I thought those were all just silly rumors, you cant really be calling on these folks. Its so not about the spine or ortho guy, Savella is a CNS drug........that = Psychiatrists and Neurologists. You maybe able to get a scrap from a Pain Spec. if you lucky but still Pain docs get the train wrecks, not the first time fibro patients. Those are at the Neuro's and Psych's. OR a very ballsy PC doc who is out in the back woods and sticks who does not have a specialist or rheum in town, then they could in a sense be a savella target, but your grasping at straws here bud. sorry bout the call plan, sounds like a set up, and intentional because it is certainly not for business strategies, if this was a Fibro launch you would be living and dying all day and all night in your Psych and Neuro offices, with Pain and Rhem in a close second! no a call panel full of Gp and Interists and surgeons.......come on thats just common sense!!!
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  #14  
Old 05-06-2009, 10:57 PM
Anonymous
 
Posts: n/a
Banghead Re: Savella

you just said the magic words-common sense! not one lick of common sense has been used in designing these call plans. They are Forest leftovers-plain & simple. Confirmed by my Forest counterpart. When Cypress reps were shown their call panels- all they could do was stare in disbelief. Anyone with even a small amount of experience would be able to tell that the docs we received were the wrong targets. Forest wanted the neuros because of the rest of their drugs they sell. So guess who got screwed? We get all the problems associated with having multiple reps in multiple territories, but not the pay that should be based on the huge territories (zips) we have.
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  #15  
Old 05-06-2009, 11:03 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
you just said the magic words-common sense! not one lick of common sense has been used in designing these call plans. They are Forest leftovers-plain & simple. Confirmed by my Forest counterpart. When Cypress reps were shown their call panels- all they could do was stare in disbelief. Anyone with even a small amount of experience would be able to tell that the docs we received were the wrong targets. Forest wanted the neuros because of the rest of their drugs they sell. So guess who got screwed? We get all the problems associated with having multiple reps in multiple territories, but not the pay that should be based on the huge territories (zips) we have.


concur. Not getting paid on total zip code will go down as one of the major gigantic management screw up in the history of this company. It is a huge slap in the face and a indicator that cypress reps days are numbered, it would have been very easy for them to pay us the correct way, but they chose the call panels only..........there is no reason for any experienced talented rep to stay with this mess of a situation..............................
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  #16  
Old 05-06-2009, 11:44 PM
Anonymous
 
Posts: n/a
Jester Re: Savella

Quote:
Originally Posted by Anonymous View Post
concur. Not getting paid on total zip code will go down as one of the major gigantic management screw up in the history of this company. It is a huge slap in the face and a indicator that cypress reps days are numbered, it would have been very easy for them to pay us the correct way, but they chose the call panels only..........there is no reason for any experienced talented rep to stay with this mess of a situation..............................
My Spinal Docs that do surgery and fusion think that Savella makes a lot of sense. HE HE hehehe. they write barely nothing and had outdated Cymbalta. We get the crap, and have to turn it into pate'
Cypress are you out of your fk'in mind? What a freakin joke.
Cypress is here to make money on stock and nothing else. You are all a bunch of nothings to them. They will abuse you and lose you in a heartbeat. Especially on the East Coast it is hard core.
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  #17  
Old 05-07-2009, 07:32 AM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Wow, I thought those were all just silly rumors, you cant really be calling on these folks. Its so not about the spine or ortho guy, Savella is a CNS drug........that = Psychiatrists and Neurologists. You maybe able to get a scrap from a Pain Spec. if you lucky but still Pain docs get the train wrecks, not the first time fibro patients. Those are at the Neuro's and Psych's. OR a very ballsy PC doc who is out in the back woods and sticks who does not have a specialist or rheum in town, then they could in a sense be a savella target, but your grasping at straws here bud. sorry bout the call plan, sounds like a set up, and intentional because it is certainly not for business strategies, if this was a Fibro launch you would be living and dying all day and all night in your Psych and Neuro offices, with Pain and Rhem in a close second! no a call panel full of Gp and Interists and surgeons.......come on thats just common sense!!!
bla bla bla cereal -girl!
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  #18  
Old 05-07-2009, 08:06 PM
Anonymous
 
Posts: n/a
Default Re: Savella

It's clear that everything that we do here is based on what will be required to fulfill the forest contract. If cypress gets paid based on the volume of scripts out of the spine docs, then that's where we are going to be required to make our calls.

It might be intersting to read a copy of the agreement that forest and cypress have with each other. Is it a public document?
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  #19  
Old 05-07-2009, 09:16 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Well I saw a couple of my Reps Forest Counterparts call list and I must say we got hosed again!! What a shit list they gave us, fucking 9/10 calls a day off a shit list of doctors, gee what a novel idea. And FUCK off to the douche bag on here trying to stick up for these blundering fuck heads, nice try but your clearly outnumbered! and it is pretty clear who you are....
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  #20  
Old 05-07-2009, 09:24 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
you just said the magic words-common sense! not one lick of common sense has been used in designing these call plans. They are Forest leftovers-plain & simple. Confirmed by my Forest counterpart. When Cypress reps were shown their call panels- all they could do was stare in disbelief. Anyone with even a small amount of experience would be able to tell that the docs we received were the wrong targets. Forest wanted the neuros because of the rest of their drugs they sell. So guess who got screwed? We get all the problems associated with having multiple reps in multiple territories, but not the pay that should be based on the huge territories (zips) we have.


some of your post is wrong. but your on the right track.
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  #21  
Old 05-08-2009, 06:47 AM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
gp eat your generic fruit loops-there in bags =save your cheeksa nickel
more complainers choke on cheap cereal -losers
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  #22  
Old 05-08-2009, 10:19 AM
Anonymous
 
Posts: n/a
Post Re: Savella

Quote:
Originally Posted by Anonymous View Post
more complainers choke on cheap cereal -losers
Read your psycho words and postings always mentioning food. they are disconnecting, immature and meaningless. Now WHO is the "Loser".
Post something that is intelligent and discernable.
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  #23  
Old 05-08-2009, 10:54 AM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Read your psycho words and postings always mentioning food. they are disconnecting, immature and meaningless. Now WHO is the "Loser".
Post something that is intelligent and discernable.
stop the hate speech- use that cornrake on your neckiemeat
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  #24  
Old 05-08-2009, 02:52 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
It's clear that everything that we do here is based on what will be required to fulfill the forest contract. If cypress gets paid based on the volume of scripts out of the spine docs, then that's where we are going to be required to make our calls.

It might be intersting to read a copy of the agreement that forest and cypress have with each other. Is it a public document?




Yes! It is a very public document. I suggest you read it. Google it. I have read it, so have many cypress reps, and its scary and revealing. It is a SEC public form, the entire contract can be found under past press releases surrounding the Forest, Cypress partnership of Savella. It should not be hard to find if you have any internet experience in typing key words.........
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  #25  
Old 05-12-2009, 04:19 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Cypress Bioscience: Investing in Pain 1 comment
by: Richard Sater May 12, 2009 | about stocks: CYPB / FRX / LLY / PFE



This Cypress Bioscience, Inc (CYPB) is a small company with a 287 million dollar market cap that will soon begin to receive royalties for its first FDA approved product. Savella (milnacipran) was approved on January 14, 2009 by the FDA for the management of FMS (Fibromyalgia Syndrome) and became available at pharmacies on April 28. This drug will be marketed by Forest Laboratories (FRX), a company that already has a large sales force marketing Namenda for Alzheimer’s and Lexapro for depression and generalized anxiety.

Fibromyalgia

Patients with fibromyalgia syndrome experience pain, fatigue, poor sleep and other symptoms. Most experience mood disorders as well. Diagnosis remains difficult due to the absence of laboratory and imaging abnormalities. Therefore, identification of the syndrome is by history and physical exam. Up to 2% of the population, with a 9:1 ratio of female to male, meets official criteria for FMS, with most people presenting in young adulthood. Thus, there are up to 6 million people in North America with this disorder.

Because of the difficulty in proper diagnosis and the interplay between psychological and physical symptoms, FMS is often difficult to treat. Though many small studies in the past showed the benefit of some older drugs like the tricyclic antidepressant and anti-epileptic agents, larger studies were not performed before this decade. Over the past two years, Lyrica (Pfizer, PFE) and Cymbalta (Lilly, LLY) received FDA approval for FMS, making Savella the third drug to receive this indication.

Many patients with FMS receive some benefit from drugs that work through central pain pathways. The ‘gate control’ theory of pain asserts that pain may be modulated in the spinal cord, before being appreciated in the brain. Older tricyclic antidepressants, such as amitriptyline, imipramine and nortriptyline, work through multiple pathways including serotonin and norepinephrine reuptake inhibition and have been used off-label for years for FMS and other pain disorders.

Unfortunately, side effects are common with these drugs, especially when used at higher dose. Cymbalta (duloxetine) was the first true dual serotonin and norepinephrine reuptake inhibitor marketed and was first approved for depression, then for anxiety, diabetic peripheral neuropathic pain and most recently for FMS.

Norepinephrine, transmitted to the gray matter of the spinal cord from neurons in the brainstem, lingers longer at the synapse when reuptake is inhibited by medications such as Cymbalta or Savella. The role of serotonin in pain is less defined.

Lyrica, a medicine first approved for epilepsy, and also approved for post-herpetic neuropathy and diabetic neuropathy, was the first medication approved for FMS in 2007. Among other actions, Lyrica works through a calcium channel that can modulate pain.

Savella

Where does Savella fit in? Savella inhibits norepinephrine and serotonin reuptake in a 3:1 ratio, where Cymbalta has this action in a 1:9 ratio. Thus, Savella is more balanced in this regard. Theoretically, Savella should be more potent for pain modulation than Cymbalta.

Reviewing the studies, side effects appear to be fairly equal, though I have not yet had the opportunity to get feedback from patients who have been prescribed Savella over the last two weeks. Cymbalta has become a blockbuster with over 2 billion in sales last year.

There is huge potential for Savella to get a very large slice of this market. Because of the favorable norepinephrine and serotonin reuptake ratio, Savella may be a better agent for FMS, though no comparison study has yet been done.

Additionally, it should be effective for neuropathic pain and depression. It has been used as an antidepressant in Europe and Japan.

Savella will have several advantages and disadvantage, compared to Cymbalta. Its higher ratio of norepinephrine and possibility of higher efficacy will be the main advantage. Its disadvantages include being a twice a day drug (vs. Cymbalta at once a day).

Compared to the generic tricyclics, Savella will be much more expensive but have a better side effect profile. Lyrica has a different mechanism of action and will be less affected by the introduction of Savella than Cymbalta. Further competition with other new agents will be avoided as Pfizer recently halted development of esreboxetine, an enantiomer of the anti-depressant reboxetine (sold in Europe) that has an even higher ratio of norepinephrine to serotonin reuptake inhibition.

I expect both Lilly and Pfizer to ramp up their marketing for their products for FMS.

Cypress Bioscience, Inc.

Cypress initially licensed milnacipran from Pierre Fabre Medicament of France for FMS and related chronic pain syndromes in North America in 2001 for payment, landmark payments and royalties. The arrangement was modified in 2003 to allow development and sales of milnacipran for any indication in North America in exchange for shares of stock and warrants. In 2004, they entered into collaboration with Forest Laboratories to further develop milnacipran and to market it. This was in exchange for upfront and milestone payments. Forest assumed future development costs for milnacipran and Cypress will receive royalties. Outside North America, Pierre Fabre controls the drug.

Cypress has a very strong balance sheet with 142 million in cash and negligible debt. Many details of the Forest and Cypress agreements have not been made public and it is unclear how much of each dollar in sales will go to Cypress. Besides Savella, Cypress has a personalized medicine division with a product, Avise PG, to help determine response to methotrexate in rheumatoid arthritis patients.

The Bull Case

Pulling the trigger to buy CYPB was difficult for several reasons. First, the absence of details regarding royalty payments to Pierre Fabre and receipts from Forest Laboratories is unsettling. However, analyst reports have estimated a 15% royalty on sales. Second, I feel Cypress (and now Forest) has done a poor job developing a potentially very useful drug.

Why have they not initiated neuropathy and depression studies? When I first followed Cypress in 2005, I decided not to buy because I disagreed with their plan to go for a FMS indication from the FDA before going for the easier depression and neuropathic pain indications. Clinical studies with depression and neuropathy would likely have yielded cleaner studies than FMS and might have led to approval of Savella one or two years earlier. For years, FMS has been treated with off-label drugs and approval for another indication would still have led to its use in this indication. Also, I’m not a big fan of the brand name --- sounds too much like saliva.

So why buy now? Sales for Savella could easily reach 500 million. If the 15% figure is correct, royalties could reach 75 million/year by 2012. Additionally, if sales ramp up quickly, Cypress will be a takeover target, most likely by their partner, Forest. Though most of Savella’s use will be for FMS, some will used be off-label for other types of pain and depression.

Furthermore, from a technical standpoint, CYPB has consistently bounced off of its 200 day moving average this year and appears to be forming a reverse head and shoulder pattern on long-term (weekly) charts. Downside risk seems limited to $5.00 as this value has held up twice in the past 4 years and share price is supported by almost $4 per share of cash and a low burn rate.
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  #26  
Old 05-12-2009, 07:31 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Forest buyout may be a blessing in disguise. Maybe as the numbers roll in from Savella things will begin to look a little brighter...if bottom line here is market share and $$$$$ to Cypress then what can management ride us about if we are producing?
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  #27  
Old 05-12-2009, 07:51 PM
Anonymous
 
Posts: n/a
Default Re: Savella

you need to sober up, this has nothing to do with producing.........it never has, take a look at your q2 IC plan, there is your answer. NOTHING to do with producing, just following orders and metrix based contract sales reporting.
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  #28  
Old 05-12-2009, 08:49 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
you need to sober up, this has nothing to do with producing.........it never has, take a look at your q2 IC plan, there is your answer. NOTHING to do with producing, just following orders and metrix based contract sales reporting.
i just upchucked a jelly creme
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  #29  
Old 05-15-2009, 12:01 AM
Anonymous
 
Posts: n/a
Default Re: Savella

I hate to do your job for you, but I hate Pfizer, so here it goes.

1. Most Lyrica is Prescribed for Neuropathic Pain and nerve injuries (off Label). Forget calling on any Spine, Ortho, or Pain Doc and expect to talk about FIbro. THEY DONT BELIEVE IN THE DISEASE AND WILL LAUGH YOU OUT OF THE CLINIC. Tell them to use your drug in pts who complain of weight gain or excessive tiredness with Lyrica.

2. Rheums are slow to uptake any drug. GO AFTER LYRICA FAILURES. Over 90% of the patients with Fibro are Female. Lyrica causes weight gain, edema, or sleppy time in 50% of patients. This is all the reps here from docs. Women will not take a drug that causes weight gain ( except big macs). You can get some serious business in a short period of time with this strategy.

Come back in a few days for a few more pointers.
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  #30  
Old 05-18-2009, 10:02 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Truth Flash: Savella is an anti-depressant. Doc's understand this. Fibro is still very much a grey area and many believe it does not even exist. Especially the low grade targets cypress got stuck with. Do some research on Savella in Europe. You will need the clinical info if you want to be semi successful with Savellla.

Managed Care coverage will trump all, if its positioned well, 2nd tier or non formulary 3rd tier as they claim, things will be shaky at best for most territories. Territories with Anthem and Wellpoint as the biggest patient lives, Well your screwed! Sorry. Yes that is you the Mid West! Dont overpromise results, Savella (Milnacipran) is going to be around for many years, Forest has the right to the reforms and tweeks in the molecule. What cypress is doing now is just playing second fiddle and trying to justify why we have a Savella Sales Force. Frankly we are not needed, and they know that (Forest) so in real terms, find a way to show some value to what your doing, remember you are not a crucial part of this Savella launch, look at your targets, think smart and be aware of the spinning and bullshit your going to hear from your DM. I bet you at the end of the day, the cypress reps will be the first ones out when Forest gets enough sample metrix data to show that our 100 troops are not needed and are minimully impactful within the Savella push. Razor sharp analysis is what I bring, no name calling, no exposing, just smart, intelligent business banter. I dont see how any of this can come out positive for cypress, unless the buy out happens sooner rather than later if they can keep this stock price slowly climbing, it might make a good buy for Forest.
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  #31  
Old 05-18-2009, 10:16 PM
Anonymous
 
Posts: n/a
Default Re: Savella

to the O P above. I fully agree.........well said and logical insight. I also am trying to find out what the cypress role is in regards to all this. It has been so inconsistant and incomplete. I think they only want us to know a little bit at a time, they want to give out a perception, nothing concrete. How long will Forest keep us hanging around? And bigger ques. why would they? I think you will start to see some answers to this shortly. Hang on folks......its going to get tight again! Thought we all took these" magical", "entrepreneural" no pods selling cypress jobs to get out of the rat race of primary care? What a huge slap in the face this is!!!
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  #32  
Old 05-18-2009, 11:44 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Truth Flash: Savella is an anti-depressant. Doc's understand this. Fibro is still very much a grey area and many believe it does not even exist. Especially the low grade targets cypress got stuck with. Do some research on Savella in Europe. You will need the clinical info if you want to be semi successful with Savellla.

Managed Care coverage will trump all, if its positioned well, 2nd tier or non formulary 3rd tier as they claim, things will be shaky at best for most territories. Territories with Anthem and Wellpoint as the biggest patient lives, Well your screwed! Sorry. Yes that is you the Mid West! Dont overpromise results, Savella (Milnacipran) is going to be around for many years, Forest has the right to the reforms and tweeks in the molecule. What cypress is doing now is just playing second fiddle and trying to justify why we have a Savella Sales Force. Frankly we are not needed, and they know that (Forest) so in real terms, find a way to show some value to what your doing, remember you are not a crucial part of this Savella launch, look at your targets, think smart and be aware of the spinning and bullshit your going to hear from your DM. I bet you at the end of the day, the cypress reps will be the first ones out when Forest gets enough sample metrix data to show that our 100 troops are not needed and are minimully impactful within the Savella push. Razor sharp analysis is what I bring, no name calling, no exposing, just smart, intelligent business banter. I dont see how any of this can come out positive for cypress, unless the buy out happens sooner rather than later if they can keep this stock price slowly climbing, it might make a good buy for Forest.
With both sales forces sharing so many targets, how do you decide which sales force is making an impact?
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  #33  
Old 05-19-2009, 11:41 PM
Anonymous
 
Posts: n/a
Lol Re: Savella

Never seen this dispensed in a pharmacy
Never heard of anyone prescribing this for any reason
Our psych professor laughed at this one
2x/day dosing
1 week titration initiation
Uncontrolled narrow-angle glaucoma contraindication
Need renal adjustment with CrCl <30
Fulminant hepatitis has been reported in patients treated with Savella
** liver problems are the #1 reason a drug is yanked from the market

Good luck guys, especially where this one lands on a formularly... especially with a generic venlafaxine ER tablet of hitting the shelves.

I suppose the brainless quantfunds will move the stock up though.
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  #34  
Old 05-20-2009, 04:37 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Never seen this dispensed in a pharmacy
Never heard of anyone prescribing this for any reason
Our psych professor laughed at this one
2x/day dosing
1 week titration initiation
Uncontrolled narrow-angle glaucoma contraindication
Need renal adjustment with CrCl <30
Fulminant hepatitis has been reported in patients treated with Savella
** liver problems are the #1 reason a drug is yanked from the market

Good luck guys, especially where this one lands on a formularly... especially with a generic venlafaxine ER tablet of hitting the shelves.

I suppose the brainless quantfunds will move the stock up though.
i agree i hate generic fruit loops
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  #35  
Old 05-20-2009, 10:54 PM
Anonymous
 
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Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Spine docs? What are you doing call on Spine Specialists? Savella is a CNS drug, Fibro is a CNS disorder, of course a spine doc or ortho would laugh you out of the office, hello?????? They cut and inject, the last thing they want to see walk in is some wacko claiming to suffer from fibro, they want to get those patients out as soon as possible.....get them back to the Psychiatrist!!!!!!!!!!

you are right, cut and inject is where the bucks are for spine docs. managing a patient's fibro is too time consuming away from the procedures that do pay.
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  #36  
Old 06-09-2009, 05:43 AM
Anonymous
 
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Default Re: Savella

OK,so how much influence do we really have on these sales numbers when we have anywhere between 10 - 15 "counterparts"?
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  #37  
Old 06-09-2009, 09:45 AM
Anonymous
 
Posts: n/a
Party Re: Savella

Quote:
Originally Posted by Anonymous View Post
go cry elsewhere baby cheeseface we need winners here!

Remember after "uncle Sam" takes his cut your take home will be roughly a paltry. $3,100.00.
Take that Cheeseface aka TC
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  #38  
Old 06-10-2009, 07:47 AM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
Remember after "uncle Sam" takes his cut your take home will be roughly a paltry. $3,100.00.
Take that Cheeseface aka TC
save it Cheswick-your words are like warm apple juice-wow!
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  #39  
Old 06-10-2009, 10:25 AM
Anonymous
 
Posts: n/a
Party Re: Savella

Quote:
Originally Posted by Anonymous View Post
save it Cheswick-your words are like warm apple juice-wow!
One of the symptoms of paranoid schizophrena is talking in word salads where the sentences don't make sense because the mentally disturbed person has disconnected thoughts due to the corpus callum being disjointed.
Observing your language and behavior, which is erratic and up / down. We all agree that you have some serious mental issues.
TC you should be very proud of your professionalism, it is inspiring as a leader. You are everying that we all aspire to be. disrespected, hated, not trusted, and more.
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  #40  
Old 06-10-2009, 03:46 PM
Anonymous
 
Posts: n/a
Default Re: Savella

Quote:
Originally Posted by Anonymous View Post
One of the symptoms of paranoid schizophrena is talking in word salads where the sentences don't make sense because the mentally disturbed person has disconnected thoughts due to the corpus callum being disjointed.
Observing your language and behavior, which is erratic and up / down. We all agree that you have some serious mental issues.
TC you should be very proud of your professionalism, it is inspiring as a leader. You are everying that we all aspire to be. disrespected, hated, not trusted, and more.
Yeah cheswick-so smart and sassy- got some smoked edam for your neckie rubmelt!
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