thanks kenny for the updates

Your updates are essentially worthless. The longer you delay telling us of our alleged backup plan, the more reason to believe we have none. Also, the longer this drags out, more reason to believe that the ultimate result is not going to be good. If we had a good case with the courts, they would have put an end to Acella immediately. It's been close to a year now with this whole cluster fuck!!!!

Just put this company out of business already! Also I have to somewhat agree, if we DID have a plan and we really had a case to begin with there would have been no reason to change formulation to 'delink'. Either Acella did something wrong, or they didn't! Bottom line, keep us in the TOTAL loop with whats going on and stick a fork in these shady assholes!

did y'all read the new JAMA article? Our snake oil product seems to have adverse event of diabetic nueropathy. I'm sure Zach will tell us that "of course it has adverse events because they study didn't use metanx" Hey Zach, FUCKYOU too!

Originally Posted by Anonymous

did y'all read the new JAMA article? Our snake oil product seems to have adverse event of diabetic nueropathy. I'm sure Zach will tell us that "of course it has adverse events because they study didn't use metanx" Hey Zach, FUCKYOU too!

Please post the Jama Article ; so the whole world can enjoy!

You pal losers have no article in Jama because you have no drugs. Pal pal pal. We work for pal!!!! Bwawawawawawa!!!! Coming mother, I know supper is getting cold!!! Damn, I am a worthless nugget.

August 6, 2010 — B vitamin supplements do not seem to significantly reduce subsequent stroke, myocardial infarction, or vascular death in patients with a history of recent stroke and ischemic attack, despite lowering of homocysteine levels.

These are the final results of the Vitamins to Prevent Stroke (VITATOPS) trial, published online August 4 in The Lancet Neurology. The findings were also presented in May at the XIX European Stroke Conference in Barcelona, Spain, and reported by Medscape Medical News at that time.

The VITATOPS trial results add to other published studies of vitamin B supplementation that have failed to demonstrate a benefit for secondary protection against vascular event.

In the VITATOPS trial, B vitamins were safe, "but they were not significantly [statistically] more effective than placebo in preventing major vascular events among stroke and TIA [transient ischemic attack] patients," Graeme J. Hankey, MD, MBBS, from the Department of Neurology, Royal Perth Hospital, Australia, noted in an email to Medscape Medical News.


REMEMBER ...these are the test the KKKamps were waiting for.

Originally Posted by Anonymous

August 6, 2010 — B vitamin supplements do not seem to significantly reduce subsequent stroke, myocardial infarction, or vascular death in patients with a history of recent stroke and ischemic attack, despite lowering of homocysteine levels.

These are the final results of the Vitamins to Prevent Stroke (VITATOPS) trial, published online August 4 in The Lancet Neurology. The findings were also presented in May at the XIX European Stroke Conference in Barcelona, Spain, and reported by Medscape Medical News at that time.

The VITATOPS trial results add to other published studies of vitamin B supplementation that have failed to demonstrate a benefit for secondary protection against vascular event.

In the VITATOPS trial, B vitamins were safe, "but they were not significantly [statistically] more effective than placebo in preventing major vascular events among stroke and TIA [transient ischemic attack] patients," Graeme J. Hankey, MD, MBBS, from the Department of Neurology, Royal Perth Hospital, Australia, noted in an email to Medscape Medical News.


REMEMBER ...these are the test the KKKamps were waiting for.

This is the lancet......it's not even a real journal. Who cares?!? Besides, metanx is for neuropathy. Geez.....

As someone who has been here 10 years and seen the 'response' to generic FOLTX and neutered our response was to that, take it from me whatever plan they have has nothing to do with being able to stop it. So we will try to discredit our competition by claiming their ingredients aren't safe or not as pure as ours. But the question is if that were true then what our competitors are doing is illegal and the courts would Havering step in, why haven't they? The fact is we have been beaten by our own game. And nobody is to blame except the company for not getting us drug protection or a legitimate product to sell. It's not the sales force's fault, the doctor's or even the pharmacist. Everyone is playing the same game the difference is someone else is playing better. Live by semantics die by semantics. Any updates that don't include "we've successfully gotten all generics off the shelf" or "all generics are being recalled" are a waste of our time. This company has skirted the ethical and moral line for some time and now that very line is being used to hang us out to dry. Our own business practices have "come home to roost."

yup, no doctor reads JAMA too.

Clinical question Are high-dose B vitamins beneficial for adults with diabetic nephropathy?

Bottom line High-dose B vitamins may actually increase the risk of adverse outcomes—including MI, stroke, and mortality—in adults with both type 1 and type 2 diabetic nephropathy. Highdose B vitamins are also either harmful or of no benefit to patients at high risk of cardiovascular disease, chronic renal failure, and cognitive impairment. The B vitamins belong on the same “Do Not Use” shelf alongside the vitamin E. (Level of evidence = 1b)

Synopsis Supplemental folic acid and B vitamins are not beneficial in adults at high risk of cardiovascular disease or in those with chronic renal failure. Whether this is also true for patients with diabetic nephropathy is unknown. These investigators identified 238 adults, 18 years or older, with type 1 or type 2 diabetes and nephropathy defined as at least 300 mg of urinary albumin excretion per day. Patients randomly received, in double-blind fashion (concealed allocation assignment), a capsule containing folic acid (2.5 mg), pyridoxine (25 mg), and cyanocobalamin (1 mg) or an identical placebo once a day. Persons assessing outcomes remained masked to treatment group assignment. Complete follow-up occurred for more than 96% of patients for a median length of 32 months. Analyses were by intention to treat. Although plasma homocysteine levels were significantly lower in the intervention group, the patients assigned to the B-vitamin group had a significantly greater reduction in renal glomerular filtration rate compared with patients in the control group. There was no difference in the need for dialysis between the two treatment groups. Most important, patients in the B-vitamin group also experienced an increased risk of the composite outcome of MI, stroke, and all-cause mortality (number needed to treat to harm = 11).

House AA, Eliasziw M, Cattran DC, et al. Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial. JAMA. 2010;303(16):1603-1609.

Originally Posted by Anonymous

yup, no doctor reads JAMA too.

Clinical question Are high-dose B vitamins beneficial for adults with diabetic nephropathy?

Bottom line High-dose B vitamins may actually increase the risk of adverse outcomes—including MI, stroke, and mortality—in adults with both type 1 and type 2 diabetic nephropathy. Highdose B vitamins are also either harmful or of no benefit to patients at high risk of cardiovascular disease, chronic renal failure, and cognitive impairment. The B vitamins belong on the same “Do Not Use” shelf alongside the vitamin E. (Level of evidence = 1b)

Synopsis Supplemental folic acid and B vitamins are not beneficial in adults at high risk of cardiovascular disease or in those with chronic renal failure. Whether this is also true for patients with diabetic nephropathy is unknown. These investigators identified 238 adults, 18 years or older, with type 1 or type 2 diabetes and nephropathy defined as at least 300 mg of urinary albumin excretion per day. Patients randomly received, in double-blind fashion (concealed allocation assignment), a capsule containing folic acid (2.5 mg), pyridoxine (25 mg), and cyanocobalamin (1 mg) or an identical placebo once a day. Persons assessing outcomes remained masked to treatment group assignment. Complete follow-up occurred for more than 96% of patients for a median length of 32 months. Analyses were by intention to treat. Although plasma homocysteine levels were significantly lower in the intervention group, the patients assigned to the B-vitamin group had a significantly greater reduction in renal glomerular filtration rate compared with patients in the control group. There was no difference in the need for dialysis between the two treatment groups. Most important, patients in the B-vitamin group also experienced an increased risk of the composite outcome of MI, stroke, and all-cause mortality (number needed to treat to harm = 11).

House AA, Eliasziw M, Cattran DC, et al. Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial. JAMA. 2010;303(16):1603-1609.

they used folic acid and cyanocobalamin. big difference smarty pants.

Metanx is for the feet and not the heart or brain. LOL

Listen all you jackasses. The snake oil we sell is in the pure form and only relevant if the patient has the poly-morphism that doesn't metabolize the b-Vitamins. So, if you do not have the poly-morphism, which is less than .000000000001% (don't quote me - but it is extremely low in the US population) than FOLTX is just fine! or what ever the generic is these days. The only reason the KKKamps went after L-Methyfolate was the clan could not protect the bogus patents they said they had. FOLTX cost pennies and made the clan allot of money.

so, by using the purest form would now hypothetically be worse according to the studies. (I'm just using KKKamp thinking now)

Keep the updates coming. god knows the Camps aren't telling us the truth!

Originally Posted by Anonymous

Listen all you jackasses. The snake oil we sell is in the pure form and only relevant if the patient has the poly-morphism that doesn't metabolize the b-Vitamins. So, if you do not have the poly-morphism, which is less than .000000000001% (don't quote me - but it is extremely low in the US population) than FOLTX is just fine! or what ever the generic is these days. The only reason the KKKamps went after L-Methyfolate was the clan could not protect the bogus patents they said they had. FOLTX cost pennies and made the clan allot of money.

so, by using the purest form would now hypothetically be worse according to the studies. (I'm just using KKKamp thinking now)

How very true! good post!

Had a doctor the other day ask me about the JAMA article. I could no longer say "hey Doc, it's a B Vitamin, it won't kill you"