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  #51  
Old 10-02-2012, 09:37 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
You all VERY WELL know that it's just marketing and advertising and capturing share !!!
ALL these drugs (in general..in the general population).. do just about what they claim to do (as long as you use them where they are supposed to be used !!)...That's a bit difficult to control ..eh ?
Just mentioning....and the result has cost us and others dearly $$$$$$$
If there is a real breakthrough we will certainly know it !!!!!
HA HA HA
But for the price, I'm sticking to 81 mg generic Aspirin.
Can't squeeze that Lemon too much more....
Next great thing???
Prove it!
Statistics don't treat patients......
And neither do Reps.
Oh good, the McDonalds chef who doesn't believe in number theory has graced our presence again. Once you get out of college you can post otherwise, you waste everyone's time. Buh-bye.
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  #52  
Old 10-03-2012, 07:39 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Oh good, the McDonalds chef who doesn't believe in number theory has graced our presence again. Once you get out of college you can post otherwise, you waste everyone's time. Buh-bye.
Would you like fries ?
Oh,..sorry, ...the prison cafe is just doing mashed potatoes today.
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  #53  
Old 10-03-2012, 12:32 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Would you like fries ?
Oh,..sorry, ...the prison cafe is just doing mashed potatoes today.
Mashed do get through the bars easier......
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  #54  
Old 10-03-2012, 12:54 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Hey Sparky, Anticoagulatiion 101....to your Point 1.....newsflash, it's not the Pradaxa or the Xarelto that dictates the need for bridging.....HELLOOOOO, it's the Coumadin!!!!!! you see, it takes Coumadin a while to become therapeutic and THAT is why you need to bridge. That statement didn't show up in your package insert because.....HELLOOOOO....your trial didn't follow patients for 30 DAYS after being taken OFF the medication. To your Point 3....this is hysterical that you would make this statement because in your trial, you didn't switch pts. to warfarin THEREFORE, YOU DO NOT KNOW THIS TO BE TRUE !!!!!!!!!!!!!!!!!!!!!!

You are obviously new to anticoagulation AND cardilogy. You know nothing about anticoagulation and you have no idea how smart cardiologists are, if you did, you would not be saying these things to them. I promise they are laughing and shaking their heads at you. I just hope all of the BI reps are this misinformed.
Patients were followed out for 3 months post Pradaxa jackass.
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  #55  
Old 10-03-2012, 06:40 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Patients were followed out for 3 months post Pradaxa jackass.
OK Sparky, tell me more about that 3 months (between Dec. 15, 2008 and March 15, 2009). How did you transition patients off of Dabigatran. Lay it out for me. What did you transition them to. What are the details. Tell me about the events that did or didn't occur. Numbers please.... This is in no way similar to the 30 day transitiion period at the end of ROCKET. Go away
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  #56  
Old 10-03-2012, 07:51 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
OK Sparky, tell me more about that 3 months (between Dec. 15, 2008 and March 15, 2009). How did you transition patients off of Dabigatran. Lay it out for me. What did you transition them to. What are the details. Tell me about the events that did or didn't occur. Numbers please.... This is in no way similar to the 30 day transitiion period at the end of ROCKET. Go away
You do understand that your data earned you a black box warning for this exact event and no matter how you try to lie we don't show the same evidence of a rebound strokes. When a person is switched off Pradaxa. By the way calling all lawyers in Ohio we had another rebound stroke with X today. My docs are now seeing why you have that warning.
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  #57  
Old 10-03-2012, 08:52 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

hellooooo, Sparkyyyy, we're waiting.....?....explain your 3 month "follow up". Where you saw 0 events.....
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  #58  
Old 10-03-2012, 09:02 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Hey Sparks, do you even know what bridging means?
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  #59  
Old 10-03-2012, 09:59 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Hey Sparks, do you even know what bridging means?
Yes, it's where you take a coumadin patient and bridge him by strengthening his dose of coumadin up so he doesn't fall down. Kind of like a bridge holding cars up while they are over water. Go get ed-u-mah-cated.
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  #60  
Old 10-03-2012, 11:03 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Yes, it's where you take a coumadin patient and bridge him by strengthening his dose of coumadin up so he doesn't fall down. Kind of like a bridge holding cars up while they are over water. Go get ed-u-mah-cated.
YIKES! I am very thankful that you are neither a physician or an architect...

yet pleased you are my competition...
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  #61  
Old 10-04-2012, 12:32 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
YIKES! I am very thankful that you are neither a physician or an architect...

yet pleased you are my competition...
After I tell them Zarelto needs this kind of coumadin bridging it seals the deal, every time. I flat out ask them if that's a problem for them, and they all frankly state they see a problem here. I am mclovin' it!
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  #62  
Old 10-04-2012, 06:57 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

EVERY DRUG NEEDS THIS KIND OF "COUMADIN BRIDGING"!!!!!
It's the Coumadin stupid!

You don't know what bridging is, do you Sparky?
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  #63  
Old 10-04-2012, 07:54 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
EVERY DRUG NEEDS THIS KIND OF "COUMADIN BRIDGING"!!!!!
It's the Coumadin stupid!

You don't know what bridging is, do you Sparky?
Sigh do you understand why you have a black box warining and Pdax doesn't is your increase risk of rebound strokes. Please understand the FDA gets the full data set and your data earned you a black box warning.
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  #64  
Old 10-04-2012, 09:32 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

thank you God, for giving us BI reps like Sparky. It makes my job alot more fun
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  #65  
Old 10-04-2012, 10:55 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Sigh do you understand why you have a black box warining and Pdax doesn't is your increase risk of rebound strokes. Please understand the FDA gets the full data set and your data earned you a black box warning.
You're as stupid as Obama in a debate. There is no "rebound", it doesn't exist. When a patient is taken off an anticoagulant their risk for stroke returns to what it was before they were being treated. Pradaxa showed it's best results in lower risk patients when coumadin wasn't optimally used, not a great data set. Pradaxa has also proven to be significantly less safe in terms of GI bleeds, all bleeds, MI and mortality since launch compared to what was seen in the studies. The black box warning clearly defines what happens and what to do when a patient must be permanently taken off Xarelto, it's clear, it's helpful and it let's every clinician understand how the med works. Now then, run along and play in your little BI douche sandbox, you're annoying and you know it.
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  #66  
Old 10-04-2012, 12:26 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
You're as stupid as Obama in a debate. There is no "rebound", it doesn't exist. When a patient is taken off an anticoagulant their risk for stroke returns to what it was before they were being treated. Pradaxa showed it's best results in lower risk patients when coumadin wasn't optimally used, not a great data set. Pradaxa has also proven to be significantly less safe in terms of GI bleeds, all bleeds, MI and mortality since launch compared to what was seen in the studies. The black box warning clearly defines what happens and what to do when a patient must be permanently taken off Xarelto, it's clear, it's helpful and it let's every clinician understand how the med works. Now then, run along and play in your little BI douche sandbox, you're annoying and you know it.
Nice spin you have there, you might ask the FDA what it thinks about minimizing your rather serious black box warning.

What was Pradaxa RR reduction in chads2 score of 3+. Seems to me your argument is that there was no benefit to using Pradaxa in the sub-pop? If you believe so I'd like to see your numbers that show this.

You also stated there was more adverse events on Pradaxa in post-marketing. Do you have the percentages (not numbers there's a difference between a number and a percentage) that show this statement provable?

You can call it rebound, you can call it more strokes, you can call it a death whistle for all I care, the danger of being on an anticoagulant is now upped when on Xarelto because a physician needs to remember to bridge when coming off your drug. That really sucks, because lawyers lie in wait for this unfortunate prescriber error and sue away any savings a physician has gathered over a life time. Since you don't have to worry about this with Pradaxa then I'd imagine it makes a physicians choice well that much easier. Do you not agree? Or, more likely, I am reading this site and see that you xarelto reps don't believe the necessary bridging with your drug.

One last thing, it seems also that you doubt that Pradaxa doesn't need bridging upon transitioning to warfarin? Can you show me where it says I should consider alternate anticoagulation when transitioning to warfarin. Is that buried in Pradaxa's PI? If you've found where it says this can you show us.

Thanks for the help I know you JnJ'ers are standup chaps.
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  #67  
Old 10-04-2012, 03:37 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Nice spin you have there, you might ask the FDA what it thinks about minimizing your rather serious black box warning.

What was Pradaxa RR reduction in chads2 score of 3+. Seems to me your argument is that there was no benefit to using Pradaxa in the sub-pop? If you believe so I'd like to see your numbers that show this.

You also stated there was more adverse events on Pradaxa in post-marketing. Do you have the percentages (not numbers there's a difference between a number and a percentage) that show this statement provable?

You can call it rebound, you can call it more strokes, you can call it a death whistle for all I care, the danger of being on an anticoagulant is now upped when on Xarelto because a physician needs to remember to bridge when coming off your drug. That really sucks, because lawyers lie in wait for this unfortunate prescriber error and sue away any savings a physician has gathered over a life time. Since you don't have to worry about this with Pradaxa then I'd imagine it makes a physicians choice well that much easier. Do you not agree? Or, more likely, I am reading this site and see that you xarelto reps don't believe the necessary bridging with your drug.

One last thing, it seems also that you doubt that Pradaxa doesn't need bridging upon transitioning to warfarin? Can you show me where it says I should consider alternate anticoagulation when transitioning to warfarin. Is that buried in Pradaxa's PI? If you've found where it says this can you show us.

Thanks for the help I know you JnJ'ers are standup chaps.
Uh, lawyer here. Give me a client that strokes out on either drug after stopping them and NOT doing what you guys call bridging. Cha-ching.
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  #68  
Old 10-04-2012, 08:29 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Nice spin you have there, you might ask the FDA what it thinks about minimizing your rather serious black box warning.

What was Pradaxa RR reduction in chads2 score of 3+. Seems to me your argument is that there was no benefit to using Pradaxa in the sub-pop? If you believe so I'd like to see your numbers that show this.

You also stated there was more adverse events on Pradaxa in post-marketing. Do you have the percentages (not numbers there's a difference between a number and a percentage) that show this statement provable?

You can call it rebound, you can call it more strokes, you can call it a death whistle for all I care, the danger of being on an anticoagulant is now upped when on Xarelto because a physician needs to remember to bridge when coming off your drug. That really sucks, because lawyers lie in wait for this unfortunate prescriber error and sue away any savings a physician has gathered over a life time. Since you don't have to worry about this with Pradaxa then I'd imagine it makes a physicians choice well that much easier. Do you not agree? Or, more likely, I am reading this site and see that you xarelto reps don't believe the necessary bridging with your drug.

One last thing, it seems also that you doubt that Pradaxa doesn't need bridging upon transitioning to warfarin? Can you show me where it says I should consider alternate anticoagulation when transitioning to warfarin. Is that buried in Pradaxa's PI? If you've found where it says this can you show us.

Thanks for the help I know you JnJ'ers are standup chaps.
Dear Obama junior,

Where did I say to minimize the black box. Nowhere. You're really stupid. The black box is straightforward and very clear yet you can't comprehend (that means you don't get it) what's written there. Ask the FDA for your impressive list of fatal bleeds and increased MI, they have the numbers. Just for fun, a little devil's advocate: If you don't need to bridge off of dapigatran is that also why standard reversal protocols don't work? Enjoy pulling your drug out of the US market!
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  #69  
Old 10-04-2012, 09:02 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Uh, lawyer here. Give me a client that strokes out on either drug after stopping them and NOT doing what you guys call bridging. Cha-ching.
Exactly, warfarin and xarelto will get you in heap um trouble. At least with Pradaxa you are in the clear and a lawsuit won't pass a prima facia test (PI says no need)
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  #70  
Old 10-04-2012, 09:39 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Dear Obama junior,

Where did I say to minimize the black box. Nowhere. You're really stupid. The black box is straightforward and very clear yet you can't comprehend (that means you don't get it) what's written there. Ask the FDA for your impressive list of fatal bleeds and increased MI, they have the numbers. Just for fun, a little devil's advocate: If you don't need to bridge off of dapigatran is that also why standard reversal protocols don't work? Enjoy pulling your drug out of the US market!
I didn't ask the FDA for numbers; I asked you. Can you even follow simple directions?
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  #71  
Old 10-04-2012, 11:44 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

when 1 week Nrxs for xarelto are 10 and pradaxas are 60+ who's really getting stomped. You have no superiority claim for stroke reduction vs warfarin. Where is your Afib data?? Your not even in the same league! xarelto is has no antidote and is highly protein bound making it difficult to be dialyzed. All you have working for you is your once a day dosing for compliance and thats nothing cuz if the patient isn't hungry and forgets to take the med then what? Then they read the black box warning get scared and call their doc. You can trick a few docs and lie but I'm getting to them 1 by 1 and setting them straight.

PS

The pradaxa rep who is taking livelihood.
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  #72  
Old 10-05-2012, 03:39 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
I didn't ask the FDA for numbers; I asked you. Can you even follow simple directions?
Greedy and dangerous little shit (aka: as you too often refer to critics as a "Douche")!!
The only numbers some of you will need to know is how many years to serve.
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  #73  
Old 10-05-2012, 05:59 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Greedy and dangerous little shit (aka: as you too often refer to critics as a "Douche")!!
The only numbers some of you will need to know is how many years to serve.
Listen, the guy claimed he knew that Post marketing of Pradaxa were higher than the trial. I didn't say that, he did. I don't say they were higher or lower, he did. All I want to know is what are those percentages he claimed he had in saying Pradaxa had higher post marketing events than the trial. It's a straight forward question, what are the percentages. I suspect he didn't have them so he evasively answered that the FDA has them. I thinks that's bullshit and a douchey thing to do - claim to have some information when you really don't. That, to me, is what a douche does, make statements up without a proof source. I don't think critics are douches, I think critics who make statements with our any proof source. No one is promoting here, we are arguing about data on a private chat board. They make bullshit statements and I call them out on it. I suggest you go back to surfing Internet porn because you can tell the difference, this site is too much for you.
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  #74  
Old 10-05-2012, 07:33 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Listen, the guy claimed he knew that Post marketing of Pradaxa were higher than the trial. I didn't say that, he did. I don't say they were higher or lower, he did. All I want to know is what are those percentages he claimed he had in saying Pradaxa had higher post marketing events than the trial. It's a straight forward question, what are the percentages. I suspect he didn't have them so he evasively answered that the FDA has them. I thinks that's bullshit and a douchey thing to do - claim to have some information when you really don't. That, to me, is what a douche does, make statements up without a proof source. I don't think critics are douches, I think critics who make statements with our any proof source. No one is promoting here, we are arguing about data on a private chat board. They make bullshit statements and I call them out on it. I suggest you go back to surfing Internet porn because you can tell the difference, this site is too much for you.
Why not just check with the FDA, or the Cleveland Clinic, or Australia or your own medical affairs department at BI. Sheesh, you're so wound up you're going to throw a clot, get yourself some Zarelto for protection!
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  #75  
Old 10-06-2012, 10:14 AM
Anonymous
 
Posts: n/a
Lol Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Why not just check with the FDA, or the Cleveland Clinic, or Australia or your own medical affairs department at BI. Sheesh, you're so wound up you're going to throw a clot, get yourself some Zarelto for protection!
I'd stay with the Leeches and blood-letting for a while, at least until ALL the data is in and fairly interpreted.

So much tension on this subject matter....mostly just idiot baiting.....
And it seems to work.... !!!!!!!!!!!
Why are a few of you (few ??) so so very very touchy ????
Hmmmmmmmmmmmmmmmmmm.......
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  #76  
Old 10-06-2012, 10:28 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
when 1 week Nrxs for xarelto are 10 and pradaxas are 60+ who's really getting stomped. You have no superiority claim for stroke reduction vs warfarin. Where is your Afib data?? Your not even in the same league! xarelto is has no antidote and is highly protein bound making it difficult to be dialyzed. All you have working for you is your once a day dosing for compliance and thats nothing cuz if the patient isn't hungry and forgets to take the med then what? Then they read the black box warning get scared and call their doc. You can trick a few docs and lie but I'm getting to them 1 by 1 and setting them straight.

PS

The pradaxa rep who is taking livelihood.
Not sure what part of the country you live in but in my part of the country #s are no where near 10 vs 60+! They are at least 50 vs 50- and Xarelto is growing everyday. And where do you live that patients "are not hungry"? not hungry at least once a day. yeah, right. I know where you are living, in fantasy land dude.
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  #77  
Old 10-06-2012, 11:13 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Why not just check with the FDA, or the Cleveland Clinic, or Australia or your own medical affairs department at BI. Sheesh, you're so wound up you're going to throw a clot, get yourself some Zarelto for protection!
You dumbass, I didn't ask the FDA, the Cleveland Clinic, etc., I asked the mofo making the statement he had the inside tract. It's a simple question that apparently you unethical reps can't answer. You see, you can't make false statements and not be called out on it.


FYI, post marketing has already been shown to be LESS than the trial. Thats a fact and provable. You can not site any percentages that support your position. I think this is not you but a failure of your training department that hires mildly educated business majors and teach them to blanket statements without accompanying proof sources. This is why JnJ has paid out more money in fines than all the fines paid by every pharmaceutical company combined since the dawn of time. See, I can do blanket statements too and all they do is weaken your point. Now, if I write, JnJ has been levied a fine of 3.3 BILLION dollars, that is way more impactful.

Lastly, I would never use Zarelto, the data was so horrible your company did 3 types of analyses on the data excluding patients so to cook the books with each analysis that the data is as muddled as how your reps think. No other company does this. Ask anyone in science about per protocol analysis or per safety analysis of data sets and they will scratch their heads and go I smell the waft of cooked data. More than likely this was done so you could say your drug was actually effective at doing something when the intent to treat showed marginal utility in the best and ineffectual utility since your warfarin comparator was abysmally used. You should get down on your knees everyday that you even have one person on this drug.
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  #78  
Old 10-06-2012, 11:26 AM
Anonymous
 
Posts: n/a
Thumbs up Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
I'd stay with the Leeches and blood-letting for a while, at least until ALL the data is in and fairly interpreted.

So much tension on this subject matter....mostly just idiot baiting.....
And it seems to work.... !!!!!!!!!!!
Why are a few of you (few ??) so so very very touchy ????
Hmmmmmmmmmmmmmmmmmm.......
That's why this country is so great - you can choose to be treated however you want. If you think the newer OACs are shit, then take warfarin, aspirins, leeches, l-touluene, whatever you think will do the trick. Why are you posting on here like we need to prove to you how great drug X or P is. That's NOT what CP is for, it's a site reps use to talk about upcoming lawoffs, who are the hottest reps, and who's easy at the out of town meetings. All other is bluster and bullshit. You clearly aren't in the industry but have need to express your rather facile notions of healthcare on here. No one cares if you uses leeches about the same amount as they don't care about your posts. I suggest you lay off here and go back to surfing porn. You bring nothing specific about science discourse and are wasting our time.

Key point: if you don't like any of these meds then DON'T take them. Is this simple enough for you to understand?
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  #79  
Old 10-06-2012, 11:55 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Dear Obama junior,

Where did I say to minimize the black box. Nowhere. You're really stupid. The black box is straightforward and very clear yet you can't comprehend (that means you don't get it) what's written there. Ask the FDA for your impressive list of fatal bleeds and increased MI, they have the numbers. Just for fun, a little devil's advocate: If you don't need to bridge off of dapigatran is that also why standard reversal protocols don't work? Enjoy pulling your drug out of the US market!
You minimized by making a blanket statement that ALL anticoagulants ivolve some sort of bridging. That's provably false. To make such an over-reaching statment is intended to minimize a rather serious aspect of Xarelto. It's on eof that oldest tricks of marketing: when you have a negative aspect on your specific product you make statemts that implie that ALL other's have this negative aspect so your choice of product SHOULDN'T be relevant.

Lets play this game:

Zidgitec cause intense burning of the penis when used for 2 hours. Plasitec was deemed by the Gubmint to really not need to consider burning of the penis issues, even though it may or may not do this. Therefore, in a rather unethical means of gather new business, widgitec training department instructs you Widgitec reps to say: Both products will cause burning of the penis if used long enough.

See how this minimizes the negative aspect of burning of the penis?

Do I need to do a second example or do you get the point. The only wrinkle is that my minimized example was a fabrication but your minimization will get people killed. Why? Well let me spell it out for you.

If you Use Pradaxa + Warfarin upon transition with another anticoagulant on top of it you might risk hyper-anticaoagulating the patient. I don't know if this happens, but I know enough to not insinuate dangerous ideas.

You will miss this point so let me state it again for you. If you nudge a doc that ALL of these new anticoagulants need some sort of bridging during warfarin transition just because yours needs to be done this way could have the negative consequence of having a Pradaxa patient bleed to death. Each drug has it's own set of rules and to deny this fact for scoring points or whatever you call popping off on here is shameful.

Is this responsible? Is this ethical? Is this freaking illegal? I await your answers.

Don't hide behind the "I didn't write that someone other than me did" because no one can tell who is who on here and if it wasn't you then you failed to speak up and set that bogus post straight. It's much easier to hide than it is to correct your own reps stupidity I guess.
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  #80  
Old 10-06-2012, 01:22 PM
Anonymous
 
Posts: n/a
Jester Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
That's why this country is so great - you can choose to be treated however you want. If you think the newer OACs are shit, then take warfarin, aspirins, leeches, l-touluene, whatever you think will do the trick. Why are you posting on here like we need to prove to you how great drug X or P is. That's NOT what CP is for, it's a site reps use to talk about upcoming lawoffs, who are the hottest reps, and who's easy at the out of town meetings. All other is bluster and bullshit. You clearly aren't in the industry but have need to express your rather facile notions of healthcare on here. No one cares if you uses leeches about the same amount as they don't care about your posts. I suggest you lay off here and go back to surfing porn. You bring nothing specific about science discourse and are wasting our time.

Key point: if you don't like any of these meds then DON'T take them. Is this simple enough for you to understand?
As mentioned earlier....
You are just TOO easy !!!!!!!!!!!!!!
:-)))))

touchy touchy touchy

catch up with you later.
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  #81  
Old 10-06-2012, 01:41 PM
Anonymous
 
Posts: n/a
Crying Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
As mentioned earlier....
You are just TOO easy !!!!!!!!!!!!!!
:-)))))

touchy touchy touchy

catch up with you later.
blah, blah ,blah-so bored of this yap- the man from Holland is painting my toe nails, Ned
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  #82  
Old 10-06-2012, 02:13 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
blah, blah ,blah-so bored of this yap- the man from Holland is painting my toe nails, Ned
All eleven ??
Extra charge for that ??
Sanding and grinding ??
HAHAHAHAHAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
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  #83  
Old 10-06-2012, 03:43 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
As mentioned earlier....
You are just TOO easy !!!!!!!!!!!!!!
:-)))))

touchy touchy touchy

catch up with you later.
My responses aren't directed to you, Mr. McDonald's Chef. They're to the other guy. You are the same one that doesn't believe in number theory or statistics and so I've already addressed you. You are butting in on a conversation that doesn't concern you.
HAAAAAHHHHHHHAHHHHAHHHHAAHHHHHHHHAHAAAAAAAHHHHHH
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  #84  
Old 10-07-2012, 07:17 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Even the FDA Cardiovascular committee voted against approving this poison, yet everyday you sell this shit to prescibers who don't know better.
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  #85  
Old 10-07-2012, 08:05 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Even the FDA Cardiovascular committee voted against approving this poison, yet everyday you sell this shit to prescibers who don't know better.
They actually voted 9-2 in favor of approval, but don't let reality skew your idiocy.
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  #86  
Old 10-07-2012, 09:12 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

You are right to bad they also said its not superior to warfarin and Nissen thinks it should be BID. Keep promoting this week ass shit

When asked if rivaroxaban merits a superior claim to warfarin, 1 out of 12 voted yes and 9 voted no; a claim as an effective alternative to warfarin, 4 voted yes and 5 voted no; a claim as effective, 7 voted yes and 3 voted no; and a claim for patients failing other anticoagulant therapy, 7 voted yes and 2 voted no.
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  #87  
Old 10-08-2012, 08:02 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
You are right to bad they also said its not superior to warfarin and Nissen thinks it should be BID. Keep promoting this week ass shit

When asked if rivaroxaban merits a superior claim to warfarin, 1 out of 12 voted yes and 9 voted no; a claim as an effective alternative to warfarin, 4 voted yes and 5 voted no; a claim as effective, 7 voted yes and 3 voted no; and a claim for patients failing other anticoagulant therapy, 7 voted yes and 2 voted no.
Sounds like a real "winner" for the exorbitant price required.
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  #88  
Old 10-08-2012, 10:23 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Sounds like a real "winner" for the exorbitant price required.
And you keep responding to your own rants Sparky. At first you were kind of funny, now your obsessive anger makes you sad and pathetic. Pop a Zarelto so you won't stroke out and go see a therapist.
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  #89  
Old 10-08-2012, 11:51 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
And you keep responding to your own rants Sparky. At first you were kind of funny, now your obsessive anger makes you sad and pathetic. Pop a Zarelto so you won't stroke out and go see a therapist.
Hey asshole, you can clearly tell that's not my writing style. I trailed several posts ago. Who cares what the breakdown was, 9-2 was final vote. Zarelto has some utility to be sure but I wouldn't make it out to be on par or better than Pradaxa especially when the data don't support this. Apixaban is effed, credible observers of data should be super weary about this drug. The good thing is that the real reasons for its now infamous year long delay will/should show up in its briefing document upon approval and we won't be kept in the dark about the rather nonspecific rejection of "data management and data verification." That concerns me enough to never let a loved on be on that drug because the data-set could be cooked. To deny this fact would most assuredly place you in the kool aid drinking camps of Pfe cheerleaders .

One last point, to the a-holes comaining about price, you need to get off the stump. If you can't or won't pay the price for a newer med then pay the price of generic warfarin and move on. Do you ever come on car blogs the car salesman use to talk about hot office staff and bitch about BMW costing more than Hyunday? No, it's completely unnecessay because if can't or won't pay the price of a BMW then there's a cheaper alternative to get from point A to B instead.
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  #90  
Old 10-08-2012, 12:00 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Hey asshole, you can clearly tell that's not my writing style. I trailed several posts ago. Who cares what the breakdown was, 9-2 was final vote. Zarelto has some utility to be sure but I wouldn't make it out to be on par or better than Pradaxa especially when the data don't support this. Apixaban is effed, credible observers of data should be super weary about this drug. The good thing is that the real reasons for its now infamous year long delay will/should show up in its briefing document upon approval and we won't be kept in the dark about the rather nonspecific rejection of "data management and data verification." That concerns me enough to never let a loved on be on that drug because the data-set could be cooked. To deny this fact would most assuredly place you in the kool aid drinking camps of Pfe cheerleaders .

One last point, to the a-holes comaining about price, you need to get off the stump. If you can't or won't pay the price for a newer med then pay the price of generic warfarin and move on. Do you ever come on car blogs the car salesman use to talk about hot office staff and bitch about BMW costing more than Hyunday? No, it's completely unnecessay because if can't or won't pay the price of a BMW then there's a cheaper alternative to get from point A to B instead.
The imbecile (and that's being kind actually)...more likely a dishonest "Cheer Leader" ....was probably referring to me......
Regardless of that....data and performance are what count in medicine.......
Like it or not...!!!!!!!!!!!!!
The world is a mess,...sadly !
:-(((((((((

Watch this:

DATA DATA DATA !!!!!

He's predictable.
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  #91  
Old 10-08-2012, 03:37 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Hey asshole, you can clearly tell that's not my writing style. I trailed several posts ago. Who cares what the breakdown was, 9-2 was final vote. Zarelto has some utility to be sure but I wouldn't make it out to be on par or better than Pradaxa especially when the data don't support this. Apixaban is effed, credible observers of data should be super weary about this drug. The good thing is that the real reasons for its now infamous year long delay will/should show up in its briefing document upon approval and we won't be kept in the dark about the rather nonspecific rejection of "data management and data verification." That concerns me enough to never let a loved on be on that drug because the data-set could be cooked. To deny this fact would most assuredly place you in the kool aid drinking camps of Pfe cheerleaders .

One last point, to the a-holes comaining about price, you need to get off the stump. If you can't or won't pay the price for a newer med then pay the price of generic warfarin and move on. Do you ever come on car blogs the car salesman use to talk about hot office staff and bitch about BMW costing more than Hyunday? No, it's completely unnecessay because if can't or won't pay the price of a BMW then there's a cheaper alternative to get from point A to B instead.
How can you compare a human being's health to owning an expensive car? Come on.
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  #92  
Old 10-08-2012, 10:02 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
How can you compare a human being's health to owning an expensive car? Come on.
Both involves choices. The analogy holds.
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  #93  
Old 10-08-2012, 10:04 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
The imbecile (and that's being kind actually)...more likely a dishonest "Cheer Leader" ....was probably referring to me......
Regardless of that....data and performance are what count in medicine.......
Like it or not...!!!!!!!!!!!!!
The world is a mess,...sadly !
:-(((((((((

Watch this:

DATA DATA DATA !!!!!

He's predictable.
Exactly, apixaban data is suspect
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  #94  
Old 10-08-2012, 11:08 PM
Anonymous
 
Posts: n/a
Arms Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Both involves choices. The analogy holds.
Analogy doesn't hold true if you're talking about relative risk.
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  #95  
Old 10-09-2012, 08:53 AM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Analogy doesn't hold true if you're talking about relative risk.
Hahaha, do you even understand what that means? Nice job parroting words.
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  #96  
Old 10-09-2012, 11:28 AM
Anonymous
 
Posts: n/a
Jester Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Hahaha, do you even understand what that means? Nice job parroting words.
Like to discuss Odds versus Likelihood Ratio ?
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  #97  
Old 10-09-2012, 12:24 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Once again for the Canadians or the euros who don't get this:

In America, you, as a patient, get to choose who will see you, what they will see you for, how you will be treated, and even, gasp, with what drug to get treated. Patients, not doctors, not husbands, not lawyers, not elves in la-las land chooses what a patient will take- the patient is presented options and then they choose what they want. Some will choose Pradaxa and ▀ome will choose warfarin for nvaf. Both drugs are approved by the FDA so the patient gets either or. Get it?
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  #98  
Old 10-10-2012, 05:21 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Was in cardio office and they just saw their first rebound stroke patient was on X hit the doughnut hole and was going back to warfarin. Anyone else have this happen
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  #99  
Old 10-10-2012, 10:48 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Was in cardio office and they just saw their first rebound stroke patient was on X hit the doughnut hole and was going back to warfarin. Anyone else have this happen
Yeah, everyday. I guess your illiteracy spills over into your ignorance and fantasy world, no?
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  #100  
Old 10-10-2012, 11:11 PM
Anonymous
 
Posts: n/a
Default Re: Xarelto Rebound Strokes

Quote:
Originally Posted by Anonymous View Post
Was in cardio office and they just saw their first rebound stroke patient was on X hit the doughnut hole and was going back to warfarin. Anyone else have this happen
So from I have been able to decipher from your gibberish is that you were at the gym (or what you call an office) on the tread mill doing your cardio for the day, eating doughnut holes (from Dunkin' Donuts? I love their coffee, it is the best!!!) when someone (I will call him "BOB") just before 'X'iting the gym, almost had a stroke because 'Bob saw his 'rebound' lover and hit your holes out of your pudgy liittle hands (BUMMER!!!! Where they the honey glazed? Soooo yummy!) on his way out to go meet first and only true lover, Warfaniqua.



This all makes as much sense as your post.
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