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  #1  
Old 02-07-2006, 07:29 AM
Anonymous
 
Posts: n/a
Default Levaquin

After reading through the old thread about Levaquin, and seeing the rampant misconceptions regarding this drug (and its parent class, fluoroquinolones), I now find that it is necessary to share my own experiences with Levaquin.

To start off, I am 24 years old, and was healthy prior to ingesting this antibiotic.
The first time I was given this drug was in December of 2003, and approximately 6 months later I partially tore a tendon in my shoulder during non-strenuous activity. This along a few other symptoms (joint pain, fatigue, muscle spasms, etc...) were never connected to the drug I was given by either myself or doctor; blood tests revealed nothing egregiously wrong, and my doctor was stumped. I recovered from my injuries, only to be given Levaquin again in December of 2004.

This time, it destroyed my life. I find myself now, over 13 months later, still nearly unable to walk due to severe tendon and nerve damage in my lower legs. I have been unable to walk for more than a few minutes at a time since January of 2005, and even standing is exceedingly difficult at times. I have now suffered from tendon problems in the following joints: feet, ankles, knees, hips, back, hands, wrists, elbows, shoulders (I would merely say all joints, but I think that I may have a toe or two which are still unaffected); I also have problems with every major muscle group in my body. The pain is indescribable, unbearable, and quite simply, cruel and inhuman punishment for the mistake of merely trusting the medical community.

The full list of my side effects (almost all of which continue to this day) is as follows:
Fatigue, severe muscle weakness/soreness, buzzing/pricking/vibratory sensations in lower legs (signs of neuropathy), popping/cracking joints, gastrointestinal problems, recurring ear pressure, difficulty finding/spelling words, severe pain/stiffness upon waking, burning pain in legs, heart palpitations/tachycardia, red/dry eyes, hair loss, brain fog, memory loss, inability to focus, mood disturbances, bouts of depersonalization/derealization, anxiety (unprovoked panic attacks, even while sleeping), depression, insomnia, electrical sensations in brain, jitteriness/shakiness, limited joint range of motion (almost every joint), cold extremities, mild occasional hallucinations, dizziness, nausea, dislocated fibular head below left knee (due to muscle weakness), periodic limb movement disorder, and others which are not easily describable in list form.

Many of you who read this may scoff, may attack me as ill-informed, or worse, a liar. I cannot change that, as mankind has a remarkable ability to ignore/disbelieve information that threatens one’s previous worldview. You are allowed to believe whatever you want, and so be it. But let me ask you this, if it was not Levaquin which caused me all of these problems, then what was it? And why did they begin occurring shortly after consuming that drug? Why are thousands of other people complaining of the exact same array of ailments after being exposed to this class of pharmaceuticals?

You can shield yourself by wrapping up snugly in disbelief, but doing so in no way changes the truth of the matter. Nor does it alleviate, prevent, or alter the suffering that we endure.

Anyone who reads this can easily choose to close to their minds to this, but what about their hearts, the basic essence of compassion and humanity which bind us as a species? People have come to you and said that they are suffering, and thus far the only retort I’ve seen is to attack them and their credibility rather than listen, try to learn, or at least offer some condolences (see the old thread for examples of the caustic replies). What do I have to gain by doing this, or making this all up? The victims of this are not ‘conspirators’, we are hurt, and seek justice. I ask for nothing more than recognition by those who perpetrate this, and help in stopping it. More importantly, what do you have to lose by listening? Market share and profit margin, the proverbial ‘bottom line’? If so, if these factors weigh more heavily on your mind than gross injustice and the cries of humanity, than I pray for you. It is too late for me, as I have already been hurt and only time may one day heal me, but if no one stands up, if education about these dangers does not proliferate, then more innocent people will end up like me today, tomorrow, and the next.

I am not asking for a complete ban on these drugs, merely that they be used as a last line of defense (which is what they were originally designed/approved for) against resistant infections where they would mean the difference between life or death, and only then in cases where the patient is fully informed. Most, nearly all, of those who have been hurt were given these drugs before any others were tried, for diagnoses that did not require them. Pushing these drugs as first line agents by playing down their toxicity profile and claiming that they are ‘safe and effective’ is a moral crime if not a legislated one (yet).

I ask that all doctors be properly educated (by the pharmaceutical representatives they rely on) as to the inherent risks associated with fluoroquinolone use. Finally, I also ask the companies who manufacture these drugs to immediately send out ‘dear doctor’ letters warning of the following three facts: that fluoroquinolones can cause adverse reactions long after treatment has been discontinued, that these adverse reactions can sometimes be completely disabling, and that they can be non-abating. Merely the truth and nothing more…to save the health and lives of your fellow man.

Is this too much to ask in return for my life?
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  #2  
Old 02-07-2006, 07:55 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Levaquin is garbage... avelox is 5 times more potent with less side effects.
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  #3  
Old 02-07-2006, 08:41 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

There were posts like this going around about a year ago. I will try and find them. It was someone who had a similar reaction to Cipro. They even had a website dedicated to telling the world that the quinolones should be used last line.
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  #4  
Old 02-07-2006, 10:29 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

I too had a horrific reaction to levaquin. My life is changed forever. I hope someone reads these posts and tries to help those of us that have become disabled because of this class of drugs.
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  #5  
Old 02-07-2006, 10:47 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

What are you people doing posting on a industry web site? Why not start your own little blog and blast us there. Frankly, we'll just ask the moderators to pull your bullshit posts and monitor for your IP address posting more.

Thanks! http://www.cafepharma.com/ubbthreads...mlins/grin.gif
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  #6  
Old 02-07-2006, 11:40 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

FYI - alot of docs don't see pharm reps, especially if they are working for an HMO (Kaiser, etc.). A lot of docs decide to write drugs out of indication on their own.
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  #7  
Old 02-07-2006, 12:43 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

What are we doing posting on an industry website? We are informing you of what it is you are doing to people. That would only bother you if you think there is something wrong with what it is you are doing. If you think there is nothing wrong with what you are doing, then these posts should not bother you at all.
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  #8  
Old 02-07-2006, 01:13 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

We are not doing anything to people, the drug is what is causing you a bad reaction. Having said that, there are a lot of risks in taking medications, especially with side effects and a competant doctor is supposed to help inform you of your condition and the drugs you are taking to help with that condition. Some drugs are miracle workers, some drugs are okay, and some cause bad reactions in patitient. It depends on the patient and how their body reacts to it, especially if you took multiple drugs that had a drug to drug interaction with one another. Some patients do great on one drug while other patients react horribly to the same drug.

I feel for your situation and I hope nothing like that ever happens to anyone whom I love. I think you need to see a different doctor and get a second opinion to help with your situation.
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  #9  
Old 02-07-2006, 02:19 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Do you inform all doctors that fluoroquinolones cause serious, long-lasting adverse reactions that can devastate the lives of victims, and therefore should only be used as a last resort? Do you tell all doctors that their patients should be fully informed of the risks before taking these drugs? If not, then you are doing this to people. As a drug rep, it is your responsibility and ethical duty to teach doctors about what these drugs can do to people. If you do not, and instead are just telling the doctors that these are wonderful drugs that work great, then you are doing these horrible things to innocent people.

By the way, levaquin was the only drug whatsoever that I had taken for over a year. So you can't blame anything else for what has happened. I could have taken a safer antibiotic for a minor infection. Instead, I was given Levaquin by a primary care doctor who simply said it was a "great antibiotic." My rheumatologist told me I was "chemically poisoned." There is no point in getting a second opinion. My life is devastated and there is absolutely nothing any doctor can do.

Yes, PLEASE warn your loved ones about the dangers of all fluoroquinolones, even if you don't warn the doctors.
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  #10  
Old 02-07-2006, 03:29 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

This is stupid, because you use this site to blast everyone else. About their families and everything else.
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  #11  
Old 02-07-2006, 04:15 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Someone posts that their life has been devastated and you call them stupid. That tells me everything I need to know. Like they said, if you don't think there's anything wrong with what you are doing, you would feel no need to attack someone who describes what you are doing.
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  #12  
Old 02-07-2006, 04:47 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Psychosomatic!!!!

some people have reactions... These are chemicals and they help people. Some people cannot tolerate them. Does that mean they are bad drugs? Go someplace else to post this nonsense. It is boring and you are wasting peoples time… you probably already heard this from a number of physicians, pharmacist, lawyers, etc Get a life.
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  #13  
Old 02-07-2006, 05:04 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

The problem is that too many people cannot tolerate FQs, plus the adverse reactions are more severe for fq's than they should be - the balance of benefit to adverse reactions is poor. Also they are being over-prescribed for minor infections when a less problematic antibiotic could be used. This is mainly because drug reps are representing them as you just did.

FQ's are a defective class of antibiotic because they are often worse than the disease that could have been cured with something safer.

What you don't realize, or at least are trying to pretend you don't realize, is that people get these symptoms, and THEN they find out that the FQ causes them. It's not the other way around, because the doctors certainly aren't telling them.

Only a sociopath could push these drugs without warning that they have a high risk of serious adverse reactions and should only be used as a last resort. Isn't that what the pharmaceutical companies themselves say??

I've never contacted a lawyer or a pharmacist. The only doctor I contacted was a rheumatologist who said everything was caused by FQ's.

When you say "this nonsense", what exactly is it you are referring to? It's on THIS website that I learned that broiler chickens have been having tendon ruptures from FQs!!! Are you saying they can read?? Are those ruptures psychosomatic? That's not a rhetorical question by the way. I'm sure you have an answer, so I'd like to hear it.

Attacking me personally only shows that you feel threatened. Do it all you want.
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  #14  
Old 02-07-2006, 05:26 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Why were you presribed Levoquin in the first place?
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  #15  
Old 02-07-2006, 05:37 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

OP - sorry to hear of your experience. On another note, I just made presidents club! WOOOOOOOOOOOOOOOO!
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  #16  
Old 02-07-2006, 06:18 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

At 24, and getting levo twice, I'm guessing a female for uti. People can have reactions, but I agree with previous posters that there's probably something elso going on. Bottom line is that levo saves a LOT more lives than it causes problems; the OP is probably just a Roche or Pfizer rep that doesn't have anything to sell anymore. The moxi poster is just a dumbass with a .25 mic and a 2% share. Drug sucks unless you want c-diff.
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  #17  
Old 02-07-2006, 06:33 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

There are several people posting here. My first post starts with "What are we doing..." And my last one before this one starts with "The problem is..." I did not write the first post in this thread. And I'm nowhere near 24!!
You need to realize that the problem we have with Levaquin is that it is being promoted by you and therefore used by doctors as a first-choice drug for minor infections, when safer antibiotics would work and without warning patients of the risks. It should only be used as a last resort when safer antibiotics have failed. But that would cut into profits, wouldn't it?
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  #18  
Old 02-07-2006, 07:01 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Last resort? Safer antibiotics? What crack are you smoking? Levaquin is extremely safe and very effective. No reason not to use it first line where appropriate.
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  #19  
Old 02-07-2006, 08:16 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

I am a 31-year-old male who went to the doctor for prostatitis, which is a common problem in men my age. I sit in a chair all day for my job, so sitting does not help the problem. I went to the doctor the first part of December. He put me on Levaquin 750 mg once a day. I started it on a Friday. That entire weekend I was very nauseated. About a week later I noticed my right Lat muscle was sore. It was weird because I had not worked out in 2 weeks, as I was gone for Thanksgiving. I body build, and knew it was a totally different pain than a "good" sore muscle. The next thing I know my joint in my shoulder was hurting, then it moved to my left shoulder joint.
I went for my follow up visit to the specialty doctor and spoke with the Nurse Practioner. He prescribed me 2 more weeks of Levaquin, over the holidays until my follow up visit on 1/6/06. I told him I was having pain down the backs of my upper thighs, butt, and joints of my shoulders. He said my condition would have nothing to do with shoulder pain.
Over the next week I got to where it hurt to get in and out of bed. The joints in my fingers and toes started hurting. Then the joints in my ankles and wrists were aching. I had piercing pains in my muscles coming from nowhere all over. My jaws started aching like I had the flu. All of this is very off and on. My left thumb joint almost ruputred. My digestive tract is all out of order. Too may anti biotics kills all the good bacteria in your body.
I have been off the Levaquin since 12/26/05. I took 27 days of the antibiotic. I had been doing some research on the Internet, and I finally told my doctor to stop the medicine. He then switched me over to Bactrim until I went for my follow up visit with the specialist. I spoke with the doctor this time and not the NP. He said the joint aches, etc...was from "Levaquin poisoning." He said the adverse reaction happens in 2 out of 99 people.
I went to my primary care doctor last Thursday, who originally prescribed the Levaquin. He ran blood tests. My CBC's were fine, but my liver enzymes were elevated. He thinks it could be from the Levaquin combined with the 2,400 mg’s of Ibuprofen I was taking (which HE told me to take). I was also taking 4 Ultracet pills a day. I already take anti-anxiety medicine. It was a total of over 20 pills a day.
Once I found out about the liver enzymes I stopped taking the Ibuprofen (MY doing). He didn’t even tell me to stop it until I suggested it to him. He said maybe I should cut back.
Since last Monday I have had a lot less joint aches. It has been very minor, but when it hits it hits hard. It will then go away as fast as it hit. I am having more nausea than I was having when I was taking the medication. I now have a kidney stone. This Levaquin has ruined the last two months of my life and is still affecting me to a degree. Pharma companies that sell this crap are evil.

If you read about the drug Ketek you will find 3 cases in Charlotte, NC one resulting in death and one of them in liver failure...almost dying. The 51 year old female that had to have a liver transplant due to this antibiotic is my mothers best friend. She is an attorney in the area. She is now on 23 medications. All I can say, is what goes around comes around. I will be telling everyone about Levaquin and I believe in due time it will be taken off the market.
I believe every person will help with the long-term effect of getting this drug off the market and helping others.
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  #20  
Old 02-07-2006, 08:20 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

I am a 31-year-old male who went to the doctor for prostatitis, which is a common problem in men my age. I sit in a chair all day for my job, so sitting does not help the problem. I went to the doctor the first part of December. He put me on Levaquin 750 mg once a day. I started it on a Friday. That entire weekend I was very nauseated. About a week later I noticed my right Lat muscle was sore. It was weird because I had not worked out in 2 weeks, as I was gone for Thanksgiving. I body build, and knew it was a totally different pain than a "good" sore muscle. The next thing I know my joint in my shoulder was hurting, then it moved to my left shoulder joint.
I went for my follow up visit to the specialty doctor and spoke with the Nurse Practioner. He prescribed me 2 more weeks of Levaquin, over the holidays until my follow up visit on 1/6/06. I told him I was having pain down the backs of my upper thighs, butt, and joints of my shoulders. He said my condition would have nothing to do with shoulder pain.
Over the next week I got to where it hurt to get in and out of bed. The joints in my fingers and toes started hurting. Then the joints in my ankles and wrists were aching. I had piercing pains in my muscles coming from nowhere all over. My jaws started aching like I had the flu. All of this is very off and on. My left thumb joint almost ruputred. My digestive tract is all out of order. Too may anti biotics kills all the good bacteria in your body.
I have been off the Levaquin since 12/26/05. I took 27 days of the antibiotic. I had been doing some research on the Internet, and I finally told my doctor to stop the medicine. He then switched me over to Bactrim until I went for my follow up visit with the specialist. I spoke with the doctor this time and not the NP. He said the joint aches, etc...was from "Levaquin poisoning." He said the adverse reaction happens in 2 out of 99 people.
I went to my primary care doctor last Thursday, who originally prescribed the Levaquin. He ran blood tests. My CBC's were fine, but my liver enzymes were elevated. He thinks it could be from the Levaquin combined with the 2,400 mg’s of Ibuprofen I was taking (which HE told me to take). I was also taking 4 Ultracet pills a day. I already take anti-anxiety medicine. It was a total of over 20 pills a day.
Once I found out about the liver enzymes I stopped taking the Ibuprofen (MY doing). He didn’t even tell me to stop it until I suggested it to him. He said maybe I should cut back.
Since last Monday I have had a lot less joint aches. It has been very minor, but when it hits it hits hard. It will then go away as fast as it hit. I am having more nausea than I was having when I was taking the medication. I now have a kidney stone. This Levaquin has ruined the last two months of my life and is still affecting me to a degree. Pharma companies that sell this crap are evil.

If you read about the drug Ketek you will find 3 cases in Charlotte, NC one resulting in death and one of them in liver failure...almost dying. The 51 year old female that had to have a liver transplant due to this antibiotic is my mothers best friend. She is an attorney in the area. She is now on 23 medications. All I can say, is what goes around comes around. I will be telling everyone about Levaquin and I believe in due time it will be taken off the market.
I believe every person will help with the long-term effect of getting this drug off the market and helping others.
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  #21  
Old 02-08-2006, 12:04 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Dick! If you are a rep you are a shitty one! Did you not know word of mouth goes a long way? Your fucked up attitude will catch up with you.
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  #22  
Old 02-08-2006, 12:18 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

If you are a drug rep...you know nothing about sales. I am a top producer in my company. I hire doctors. Levaquin is causing problems in over 2 percent (and rising) of the people taking the drug. Reps are not educated on what they are selling. I KNOW this because my girlfriend is the personal nurse for a doctor. It is all about making your sale. Good sales people are honest. Yes, doctors should take more upon themselves to research these drugs, but YOU the rep should be EDUCATED. You know getting a job in sales requires NOTHING. I have a business and psych degree and could get a job selling Cheerios to doctors offices ( about how they are healthy for you ) and be succesful. It is not rocket science, but what makes the rep Number 1 is that he/she KNOWS their product. Pharm reps SHOULD be required to have some sort of medical degree, not a background in selling vacuum cleaners.
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  #23  
Old 02-08-2006, 06:39 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

I am the person who originally started this thread, and this is my second post; unfortunately the ‘anonymous’ status of all of us makes it fairly difficult to discern this. I do, however, want to thank those of you who came to my side and helped defend my position against the unwarranted attacks that some people chose to respond with (rather than reasoned, logical dialogue, coupled with open-mindedness and maybe even a little empathy I might add).

To set the record straight, I am a male, I was 22 the first time I was given Levaquin, and 23 the next. I spent my 24th birthday sitting on a couch in terrible pain seven months after the last pill was taken. The prescription was written (both times) for bronchitis along with a sinus infection. I have taken many antibiotics over the years for these conditions, as they are recurring, and never have I had anything more than an upset stomach as a side effect. I also was not taking any medications or anything else that is contraindicated for use with Levaquin. Many subsequent tests have shown that nothing else is wrong with me, every doctor/pharmacist/specialist I have spoken with has agreed that Levaquin caused my condition.

I find the level of offense that has been taken to my post to be fairly puzzling, as I did not in any way attack any of you personally. The fact that you took it that way, rather than what my true intent was (which is quite evident in my post) I think speaks, as someone already stated, to your own feelings of being threatened, which I cannot prevent. The simple fact that this drug, which should quite a minor portion of your life, all things considered, is something that you are willing to defend so vigorously and hatefully, is, quite honestly, rather frightening.

All I can say to that is, if I was in your position, selling pharmaceuticals (or any goods for that matter), and people started coming to me complaining that the product I was selling was injurious in any way, I would certainly not respond with vehemence and petty name-calling. I would respond with incredulity at first, to be sure, but would at least listen and try to educate myself about the matter at hand. I would then react with horror that, even if it is only in some small way, I may have inadvertently contributed to someone’s pain.

To clarify my position, I am not, nor was I ever, ‘blasting’ any of you; I merely tried to put myself in your position, and having done that, I came to the conclusion that I would want to know the truth about the products I was promoting.

Do you not even care? Are you completely unwilling to listen to the concerns of your fellow humans, or is your own self-interest that great that telling me to shut up and go away becomes more than just a knee-jerk response and actually epitomizes your position toward those who would disagree with you?

As to banning me, before coming here, I thoroughly read the posting policy on this site, and I have taken care not to violate any of those rules. In fact, this policy clearly states that freedom of speech is held in high regard on this site. Attempting to silence a detractor, it would seem to me, is a greater violation of this ethos than anything I have done. Besides, I’ve noticed, imbedded in multiple other threads on this site, wanton instances of obscenity and name-calling, verbal abuse, etc… While I don’t particularly care about those things (I believe in free speech), I find it fairly odd that you find that okay and are willing to ignore it, but what I’m doing here (merely trying to educate people while sharing my story) is somehow horribly offensive and should be stopped at all cost.

Psychosomatic? The flaw in this particular argument is that the first time I was given this drug, I knew nothing about the side-effects; I never even read the pamphlet they gave me at the pharmacy because I thought it was just like every other antibiotic I’d taken. As I stated in my other post, I began having the more severe side-effects from it after I stopped taking it. A couple of months after taking it, I began waking up with shoulder pain (tendonitis), a few months after that, I partially tore a rotator cuff while emptying a dishwasher. No one ever connected the drug to these problems or any other aspect of my reaction, and the thought never even occurred to me that an antibiotic I’d taken months prior could have been doing it. Physical therapy helped me recover, and I felt great by the time I was prescribed Levaquin again. Again, it was after I started having problems that I began researching Levaquin and connected everything together. Had I not been injured, I never would have known about the possible adverse reactions from fluoroquinolones. Mass hysteria is a fallacious argument, and in no way fits in with the maladies the victims of this report.

I hope you realize that the crux of this argument is basically that I (and we, the victims) read the wrong thing (warnings about these drugs, studies, etc…), and now we are injured because we read it, not because of the drug. The inherent absurdity of this argument (that reading certain words can cause disability) should make the act of refuting it completely unnecessary. Please study some basic human psychology before using such terminology.

Being that I have no medically identifiable disease, there are only two options as to what has caused my condition.
1. Levaquin. The full prescribing information lists basically all of my ailments as possible reactions to this drug. There are countless well-researched studies that back up my claims. Not to mention thousands of anecdotal stories written by victims all detailing the same array of ailments. My problems started after consuming this drug, and every doctor I’ve seen says that Levaquin did this, and is doing this to other people.
2. A Cripple Fairy manifested herself and hit me over the head with her disability wand.

Occam’s Razor (and common sense) decrees that the first option must be true.

Finally, as to the ‘get a life’ comment that someone posted. I had a life, I liked it; Levaquin ruined it. You may not care, but I do; and I will do everything in my power to stop this from needlessly happening to other people. Basic human principles of compassion, empathy, and caring force me to do so. Like I said in my first post, a person can believe what he/she wants to, that is their right. I can say whatever I want to, and according to the policies of this site, that is also my right. Belief, or in this case, disbelief, does not and cannot change the truth. Believe what you want.

Do you really think that, if given the choice, I would be sitting here typing this stuff if I could merely get up and go do something else? I would personally love to turn around and walk across the room (pain-free), go upstairs, go outside and run around freely like a crazed chipmunk, however, the reality that my legs are damaged stops me from doing so. Again, reality trumps belief.

Some arguments here seem to be that I just have some sort of beef with fluoroquinolone antibiotics; that this animosity I have toward them is unfounded and appeared out of nowhere. I have nothing to gain personally by doing this, and the truth of the matter is that it hurts my hands to type so much. Please think about this for a moment, and then from now on use logic if you wish to argue with me. I did not come here looking for an argument and I tried my best in my other post to prevent one by clearly stating the facts of the matter and my goals with what I am doing.

After being hurt, I found the websites devoted to these drugs. I spent hours reading the horror stories of those who have been hurt as bad as or even worse than I have been. How anyone can read those stories, can think of the lives they represent, the daily struggle that the authors are now forced to go through, and react not with anger toward the cause of their suffering, but with anger toward them, is beyond me. To take a dollar sign or a previously held notion and place it in front of and above their lives is the greatest affront to both justice and humanity that I have ever seen.

All I have asked is that you listen, and learn; I have done you no harm and deserve no reproach.
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  #24  
Old 02-08-2006, 07:41 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Yawn! This really is not the forum for your issue my young friend. Especially with the length you choose to write.

Ockham's razor? (OH, and that is the correct spelling, by the way.) Great reference! Although 99% of the people on this site will have no clue what it means. Even if you explain it!

Good luck, it sounds like you'll need it.
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  #25  
Old 02-08-2006, 08:12 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Its ok Levaquin has been losing market share for the past few years to Avelox and Tequin which are much better quins than Levaquin, with less side effects as well.
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  #26  
Old 02-08-2006, 08:25 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Debating the difference between Avelox, Tequin, and Levaquin, is much like debating the differences between arsenic and cyanide. While less poisonous than those, fluoroquinolones are basically all the same as each other, and have the most of the same range of side effects. Slight differences in chemical makeup doesn't change much. Over half of all fluoroquinolones that have been approved have since been banned and/or restricted for killing/maiming too many people.

They all have their body counts and groups of people crying out in severe pain wondering how the medical community could have done this to them.

There are more important things in this world than market share.
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  #27  
Old 02-08-2006, 08:44 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

[ QUOTE ]
Yawn! This really is not the forum for your issue my young friend. Especially with the length you choose to write.

Ockham's razor? (OH, and that is the correct spelling, by the way.) Great reference! Although 99% of the people on this site will have no clue what it means. Even if you explain it!

Good luck, it sounds like you'll need it.

[/ QUOTE ]

Occam is the correct spelling, although Ockam is accepted.

But please explain WHY a forum for Levaquin drug reps is not the place to talk about adverse reactions to Levaquin. That would be a really interesting post. I would not be bored reading that one.
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  #28  
Old 02-08-2006, 09:04 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

[ QUOTE ]
Last resort? Safer antibiotics? What crack are you smoking? Levaquin is extremely safe and very effective. No reason not to use it first line where appropriate.

[/ QUOTE ]

The problem with Levaquin, and all FQs, is that they are too effective. They destroy bacteria, sure, and everything else in their path.

Levaquin is a totally made-up chemical concoction, that was shown to kill bacteria. Being a made-up chemical, there was no telling what else it would do to the human body. But hey! We don't need to mention that, do we!!! Call it "EFFECTIVE", because it certainly is. Just don't call it safe.

Do drug reps have a code of ethics?
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  #29  
Old 02-08-2006, 01:24 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Fact is this guy or "whatever" "it" is, is probably not even a drug rep. If so, then "it" could answer the question. If a rep, probably someone that is pissed because they can't make quota and are having to search for that special vacuum cleaner sales job. That's what happens when you don't know your product. I am the top producer where I work and have been for 5 years. I have been the top producer at every company I have worked in doing sales. Problem is, anyone will hire a sales person. I have two degrees...business and psych, but you don't even need a degree to do sales. I was offered 5 out of 5 jobs with pharma companies right out of college. Oh just fyi, pharma reps, I heard Carmax is hiring!
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  #30  
Old 02-08-2006, 01:55 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

I used to be a rep for Levaquin, and I first of all, just want to say I am so sorry for what has happened to you. I can understand your concerns and just wanted to respond from a reps point of view.

Ruptured tendon is a potential severe side effect of ALL quinolones, not just Levaquin. It is well-known by phycisians and pharma representatives, which is why we are not promoting Levaquin for minor infections. Most physicians will tell you they reserve Levaquin for patients who have recurrent infections (similar to what you mentioned about having recurrent bronchitis or sinusitis). Or they will use it for older people who may have developed resistant pathogens. It should never be given first line, and we definitely are not out there promoting that it should be.

There are rare situations where this happens to patients...and it is very unfortunate. There are hundreds of drugs on the market where there is a small chance (ie: 2%) that severe side effects can occur. Levaquin is a great product and has saved many individual's lives...especially those with pneumonia...and has kept many out of the hospital. Again, I am very sympathetic to your situation...but just wanted to let you know we are not out there trying to get Levaquin to be used first line. My goal is to keep physicians informed about new indications, resistance/susceptibility rates, new studies, and of course side effects. Because Levaquin has been around for so long...99% of physicians are completely aware of the side effects for Levaquin.
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  #31  
Old 02-08-2006, 02:24 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Thank you for your professional reply. I will have to say my doctor acted puzzled that this was the result of Levaquin. He did say he had heard of these ADR's, but not to this degree. The NP that I saw at the urologist, read from a drug book the Levaquin side effects and said this is not from the medicine. Come to find out the guy was younger than I am. He is probably 28 or 29. He was actually in a rival fraternity where I went to school. He was probably reading the 2001 medical almanac that I saw there in the office I was sitting in.

The actual specialist said it was from "Levaquin poisining". He did say that was the case of all quinilones. You are very right about that.

It is just unfortunate that the docs don't know enough about the drug. I am sure a drug rep with your attitude educates them on this. I can't say so for the other people, or "so called" drug reps on this site.

Anyways, take care and have a good one.
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  #32  
Old 02-08-2006, 02:26 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

I think we should table this discussion until the last week of April, at that point I'll be glad to moderate from the beach at Cabo! Thanks!
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  #33  
Old 02-08-2006, 02:53 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

I am already at the beach. I am literally retired at age 31. Beat that!
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  #34  
Old 02-09-2006, 02:53 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

AEs are bound to come up when so many patients have used Levaquin. 400M. Just wait until Drs start writing Avelox as often as Levaquin. Wait - that'll never fuckin happen. Nevermind.
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  #35  
Old 02-09-2006, 02:59 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

No matter which advantages levaquin has. It is a big problem, that it is so difficult to be treated for these ADR. And it is difficult to be treated because no one believes you. We need enlightening the interests working against diagnosing drug ADR.
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  #36  
Old 02-09-2006, 08:55 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

[ QUOTE ]
I think we should table this discussion until the last week of April, at that point I'll be glad to moderate from the beach at Cabo! Thanks!

[/ QUOTE ]

Oooh good luck. I heard Cabo is having a huge roach infestation in restaurants and hotels, and 20 people have died of food poisoning there in the last year.
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  #37  
Old 02-09-2006, 11:05 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

[ QUOTE ]
I used to be a rep for Levaquin, and I first of all, just want to say I am so sorry for what has happened to you. I can understand your concerns and just wanted to respond from a reps point of view.

Ruptured tendon is a potential severe side effect of ALL quinolones, not just Levaquin. It is well-known by phycisians and pharma representatives, which is why we are not promoting Levaquin for minor infections. Most physicians will tell you they reserve Levaquin for patients who have recurrent infections (similar to what you mentioned about having recurrent bronchitis or sinusitis). Or they will use it for older people who may have developed resistant pathogens. It should never be given first line, and we definitely are not out there promoting that it should be.

There are rare situations where this happens to patients...and it is very unfortunate. There are hundreds of drugs on the market where there is a small chance (ie: 2%) that severe side effects can occur. Levaquin is a great product and has saved many individual's lives...especially those with pneumonia...and has kept many out of the hospital. Again, I am very sympathetic to your situation...but just wanted to let you know we are not out there trying to get Levaquin to be used first line. My goal is to keep physicians informed about new indications, resistance/susceptibility rates, new studies, and of course side effects. Because Levaquin has been around for so long...99% of physicians are completely aware of the side effects for Levaquin.

[/ QUOTE ]

Thanks for your concern. We all know that tendon rupture is a class effect of all FQs. However OMP makes Levaquin and this is a thread for Levaquin. There are many more devastating ADRs for Levaquin and other FQs in addition to tendon rupture, especially among people who take more than a few pills.

No one with a conscience could promote this drug as anything but a rarely used antibiotic of last resort, only to be used with caution for someone who would die otherwise, and not routinely handed out like candy by ignorant doctors, like it is now. By the way, 2% severe adverse reactions is NOT rare. That's a huge number, and in fact the rate is probably much higher, since many severe reactions are not linked back to the drug since doctors are not willing to admit that a drug they prescribed has done something so bad to a person, and/or the victim goes to a different doctor when the ADRs hit them.

And sociopathy is no more rare than ADRs to FQs, so there are PLENTY of people around willing to lie about these poisons to doctors for the sake of money.
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  #38  
Old 02-09-2006, 08:02 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

The reason that this is not the place to post your issues with Levaquin is because the majority of people that look at this site are in fact brainwashed drug reps.

It's all about brainwashing and marketing tactics set way above our heads, and we just do what we're told.

All I can say, is that life is tough, but look around, and I bet you'll see that someone has it tougher than you. You gotta move past what happened to you and go on with your life. If you think your life's destiny is to stop fluoroquinolone use...then go for it. But remember, these drugs help people way more than they hurt people, and you could find serious side effects with every drug on the market...every single one.
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  #39  
Old 02-10-2006, 10:12 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

[ QUOTE ]
The reason that this is not the place to post your issues with Levaquin is because the majority of people that look at this site are in fact brainwashed drug reps.

It's all about brainwashing and marketing tactics set way above our heads, and we just do what we're told.

All I can say, is that life is tough, but look around, and I bet you'll see that someone has it tougher than you. You gotta move past what happened to you and go on with your life. If you think your life's destiny is to stop fluoroquinolone use...then go for it. But remember, these drugs help people way more than they hurt people, and you could find serious side effects with every drug on the market...every single one.

[/ QUOTE ]


.......and your point is???????
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  #40  
Old 02-11-2006, 08:10 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Hello again, I too wish to thank that one (former) rep for his reply. However, if 99% of doctors knew of the dangers of fluoroquinolone use, then I wouldn’t have resorted to posting here, nor would thousands of other victims be sharing their stories with the world right now. I commend that person’s reply and the fact that they said that they took the time to properly educate the doctors they personally sold Levaquin too. But again, this is obviously not happening on a large enough scale to prevent massive numbers of severe, avoidable adverse reactions.

According to a study done at University of Pennsylvania School of Medicine, out of a random sample of 100 prescriptions written for fluoroquinolones in hospital emergency rooms, only one of these scripts was written for the right diagnosis with the right dosage and for the correct length of treatment. Obviously, doctors are not being properly educated regarding these drugs.

Where the fault lies with this, I believe, is a non-issue compared with finding the means to end it.

If, as has been stated earlier in this thread, the severe reaction rate to these drugs is somewhere around 2%, and given nearly over 12 million scripts for Levaquin in 2004, and 9 million for Cipro in the same time period, then the total number of severe reaction for these two drugs alone is somewhere in the neighborhood of 420,000 per year. Extrapolate that data over a decade, and the total number affected is in the millions. Many of these people have no idea what is wrong with them, due to the fact that neither they nor their doctors were ever told that side effects can appear months after they stop taking these drugs. Close to 90% of victims are told by the prescribing doctor that their symptoms have nothing to do with the drug they took; many are told to continue taking them even after complaining of muscle, tendon and/or nerve pain.

With the sheer number of prescriptions written, the idea that these drugs are not being handed out unnecessarily is laughable. Also, the idea that ‘millions of people’s lives have been saved’ is also quite facetious, because it can be shown that many of those same lives could have been saved with safer antibiotics. This is not to say that they should be banned, merely restricted to cases where their live-saving abilities will be best served and the benefits will clearly outweigh the severe risks involved.

To the person who told me to ‘get on with my life,’ while good advice in some situations, I find that attitude to be indicative of naivety regarding what it is truly like to be in nearly constant severe pain with limited use of one’s arms and legs. I do however agree with you that there are people in this world who are worse off than I am.

Case in point: a 16 year girl given Levaquin for a sinus infection who collapses at school on the fifth day of treatment. Massive damage ensues, 29 orthopedic casts on her arms and legs are required over the next few years to prevent tendon rupture, and she ends up in a motorized scooter, possibly permanently, with limited use of her arms as well.

Levaquin is now in clinical trials for babies as young as 6 months old.

A previously healthy 57 year old man, given Levaquin, takes one pill. The next nine months of his life are plagued with severe untreatable insomnia resulting in extreme sleep deprivation and pain until, at this time, he cannot take it anymore and chooses to end his own life.

I could go on and on and on and on. I would agree that these people are worse off than I am. That is why I am so adamant in doing this, and will continue to try to the best of my ability to stop this from happening to others.

I should probably stop this before I being boring you all again. Thanks, and again, I do not wish to attack and/or offend anyone here; I merely see a grave injustice happening in the world, and I cannot for the life me sit back and do nothing while people suffer.
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  #41  
Old 02-11-2006, 08:53 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Too late Pal, you are boring. Get a life, and maybe that will go away.
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  #42  
Old 02-11-2006, 09:19 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

While I applaud those reps who atempt to make this a mature thread, I think we have multiple posters and posers here fishing for infor or trying to demoralize us.
For example, at least one poster mentioned "Bactrim" was later prescribed. While this antibiotic is used for less severe infections, is the poster aware of its dangers?? Stevens-Johnson syndrome is a well known side effect of Bacrtim-much more common than tendon rupture with Levaquin use (FACT!). SJS is basically an incurable skin disease that more than 1 in 10 people DIE from if they contract it. Soooo, you can see why a physician might reach for a drug like Levaquin.
On a personal note, I have in fact been hospitalized by a drug side effect-a very commonly used drug and known, but rare side effect--just like tendon rupture with levaquin.
so, I can sympathize with you condition, but you must understand, ALL DRUGS CARRY POTENTIALLY SERIOUS, HARMFUL SIDE EFFECTS. Even if they are widely and safely prescirbed for MOST people, if you are that ONE person, look out!
On a factual note, the 2% number used here is way out of line. according to the PI, its way less. Also, levaquin is the most prescribed quinolone, but has less of a case history of tendon rupture than cipro.
Bottom line, it is a class effect, a rare one at that, but of course very serious if you are that one person; However, this is the case with EVERY SINGLE DRUG ON THE MARKET.
Most doctors understand this, but patients who are looking for an immediate cure rarely pay attention to the potential downside of drugs.
Think on this my friends.
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  #43  
Old 02-11-2006, 10:54 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

__________________________________________________
While I applaud those reps who atempt to make this a mature thread, I think we have multiple posters and posers here fishing for infor or trying to demoralize us.
For example, at least one poster mentioned "Bactrim" was later prescribed. While this antibiotic is used for less severe infections, is the poster aware of its dangers?? Stevens-Johnson syndrome is a well known side effect of Bacrtim-much more common than tendon rupture with Levaquin use (FACT!). SJS is basically an incurable skin disease that more than 1 in 10 people DIE from if they contract it. Soooo, you can see why a physician might reach for a drug like Levaquin.
On a personal note, I have in fact been hospitalized by a drug side effect-a very commonly used drug and known, but rare side effect--just like tendon rupture with levaquin.
so, I can sympathize with you condition, but you must understand, ALL DRUGS CARRY POTENTIALLY SERIOUS, HARMFUL SIDE EFFECTS. Even if they are widely and safely prescirbed for MOST people, if you are that ONE person, look out!
On a factual note, the 2% number used here is way out of line. according to the PI, its way less. Also, levaquin is the most prescribed quinolone, but has less of a case history of tendon rupture than cipro.
Bottom line, it is a class effect, a rare one at that, but of course very serious if you are that one person; However, this is the case with EVERY SINGLE DRUG ON THE MARKET.
Most doctors understand this, but patients who are looking for an immediate cure rarely pay attention to the potential downside of drugs.
Think on this my friends.
__________________________________________________
I will say, at least your response was mature. I do understand what you are saying. Yes, the Bactrim I only took for about 10 days. By this time, I was hurting so bad from the Levaquin, I couldn't tell you if it had any different ADR's. I just finally decided to stop all the anti's.

I was told 2% by my Urologist. He said that he sees 2 to 3 males a week in their 30's for prostatitis, and that since it is happening to 50% of males, that with that number, he was going to start with less potent drugs and then go to Levaquin if he had to.

Everybody reacts to things differently. People die from allergies. It is crazy. I do understand your point, it is just that it is damaging when it happens to you, and you used to compete in body building competitions, NEVER sit at home, NEVER even thought of getting on the computer. My life was so full and busy that I was only at home to sleep. I don't party, and I quit drinking 5 years ago. I was just active. My joint pain is better than before. I just feel for those that are going through this after more than just 3 months that I have been.
You have been there it appears, so I am sure this is why your post is mature. Have a good weekend.
B
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  #44  
Old 02-11-2006, 12:05 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

To the original poster:
My, my, for someone with the laundry list of ailments you claim to have including CNS issues precluding lucid thought you sure can type one hell of a well-thought letter. I suspect, as many of my foul-mouthed brethren, that you are a slimy, shit eating bottom feading tort lawyer just casting a net out there to use in what you hope will be a class action suit in the backwaters of Mississippi where you read aloud the disdainful comments that supposed representatives of J&J said about the pain and emotional distress you now have from taking a drug. You know what, just go back to your semen crusted Grisham novels and conjure up another way to to bilk corporations out of their money.
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  #45  
Old 02-11-2006, 12:33 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

[ QUOTE ]
Too late Pal, you are boring. Get a life, and maybe that will go away.

[/ QUOTE ]

This is a very weak response. It shows that there is no defense of what you are doing. You have nothing to say but that someone ELSE is boring. I also notice that you did not actually disagree with the poster's very informative and compelling post. That says a lot right there.

Please don't bore everyone with another lame response like saying someone else is boring. Nothing could be more boring, which you don't even realize.
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  #46  
Old 02-11-2006, 12:54 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

It is well known that pharmaceutical companies rig their studies to show a lower incidence of side effects and adverse reactions, and to show milder ones as well. Adverse reactions to Levaquin are also under-reported by doctors because 1 - in spite of the list of reactions in the PDR, they seem to think these things don't really happen or they don't even read the PDR, 2 - if they do admit to themselves that they happen, they are not going to admit to the patient that a drug they prescribed damaged the patient, 3 - patients with adverse reactions very often don't link them back to a seemingly unrelated drug and never discover the connection.

And what is completely ignored by the drug companies, the FDA and doctors is that the incidence of adverse reactions to Levaquin and other FQs goes up the more pills a person takes, even over a period of several years. There is no study out there that has studied that, for the obvious reason that it would not be in the financial interest of the drug companies to do so.

In short, adverse reactions to Levaquin are in all probability grossly under-reported.
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  #47  
Old 02-11-2006, 01:35 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

LEVAQUIN SUCKS!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
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  #48  
Old 02-12-2006, 10:52 PM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Back on your meds and leave the computer alone.
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  #49  
Old 02-13-2006, 08:37 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Without realizing it, you are "killing the goose that laid the golden egg." You are creating a whole new set of people who will never take another prescription drug again and who warn everyone they know against taking prescription drugs. You are driving away your own customers with your lousy drugs and your deceitful sales practices.
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  #50  
Old 02-13-2006, 09:24 AM
Anonymous
 
Posts: n/a
Default Re: Levaquin

Who is "you". The Levo sales force, or all drug reps or who? We are creating a whole new set of people who will never take prescription drugs? Lousy drugs? My question is, who are you? These "lousy drugs" have saved millions of lives, given people a quality of life their parents or grandparents never knew. I am plenty old enough to remember the 1950's, and know that many people died in their 60s or 70s, and that cancer was a death certificate. The modern antibiotics have saved millions from pneumonia and other serious infections that were a death certificate before 1940. You are sadly mistaken to call them "lousy drugs". What is your agenda? And why are you on a drug reps site if you feel that way? Deceitful sales practices? Finally you said something that has some truth to it. Some companies are much worse than others. Being an old time Rep, I think Levo has been sold more ethically than most antibiotics, such as Z-Pak or Moxi, but we could do better no doubt. The push from the companies for more and more market share is not conducive to responsible marketing. Only the FDA can rein that in, not the individual Reps(the companies won't because the competition won't). Better think things through more clearly before you call something lousy. People throughout the third world would love to have our "lousy drugs".
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