Full Article: https://www.ucsf.edu/news/2020/04/417321/nature-publication-presents-new-blueprint-revealing-how-sars-cov-2-virus Caution Urged for Dextromethorphan Finally, the cough suppressant dextromethorphan, which acts on Sigma1 receptors, promoted viral infection in the laboratory experiments, and the researchers said that its use merits caution and warrants further study in the context of COVID-19.