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Discussion in 'Janssen' started by Anonymous, Jul 14, 2009 at 12:29 PM.
Has anyone hurd of anything about the new Invega shot coming out called Invega Sustenna.
Yes, being launched in Q4 2010
yea right.....try q4 2009!!
The pdufa is 8/4/09
Re: Invega Sustenna (paliperidone palmitate)
Attribute**RISPERDAL®CONSTA®***INVEGA®SUSTENNA™Robust efficacy profile Favorable tolerability profile, Administration every 4 weeks, No oral supplementation, Multiple administration sites, Small gauge needle, Storage and preparation (no reconstitution or refrigeration necessary)
This will be led by a team led by Lynda Benton, who did a great job with both Risperdal oral and Concerta. Look for some really good things
A quick review is:
First study with pali did not separate from Ris Consta = dose was too low.
Second study at a higher dose looks very good vs. Ris Consta.
Advantages vs. Consta:
works from day one
no titration from oral drugs
side effects were less than consta
efficacy similar, but once a month injection vs. every 2 weeks
no more beads (micro spheres)
works gluteal or deltoid
3 Fixed Doses (25 mg eq., 100 mg eq., and 150 mg eq.
INVEGA SUSTENNA WAS APPROVED ON FRIDAY (July 31).
I have never been more proud to be a part of Janssen! Invega Sustenna is a revolutionary product that will change the landscape of pyschiatric medicine. I am so excited to go out and sell this great product.
How are the patients responding to Invega Sustenna?
Any bad side effects happening?
Any complaints about cost?
Saphris will dominate the APS market, Invega and Sustena are done.
The four week formulation of INVEGA SUSTENNA (PALIPERIDONE PALMITATE) will replace the two week formulation of RISPERDAL CONSTA. INVEGA SUSTENNA works from day one and oral pills do not have to be taken for 3 weeks when starting like RISPERDAL CONSTA does. Invega is the follow up medication to Risperdal so the medication is generally better. Two injections shots have to be given the first week of SUSTENNA. Then once every 4 weeks.
Initiate INVEGA SUSTENNA with a dose of 234 mg on treatment day 1 and
156 mg one week later, both administered in the deltoid muscle. The recommended
monthly maintenance dose is 117 mg
Prefilled syringes containing 39 mg, 78 mg, 117 mg, 156 mg, or 234 mg paliperidone
and first month cost = $2,500.00? unbelievable!
What's the cost of the monthly maintenance dose 117 mg?