Reuters: Bydureon Falls Short of Victoza!

Anonymous · Oct 9, 2012 at 11:56 PM

You are all crazy. I have been prescribed Bhetta and now Bydureon. The later is not a pleasant experience. Neither did anything for my numbers. You all really make me take a look at the people pushing these messages where I work. Sad.

Donna T

Anonymous · Oct 9, 2012 at 11:57 PM

Anonymous said: ↑

You are all crazy. I have been prescribed Bhetta and now Bydureon. The later is not a pleasant experience. Neither did anything for my numbers. You all really make me take a look at the people pushing these messages where I work. Sad.

Donna T
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Sorry...meds where I work

Anonymous · Oct 10, 2012 at 7:59 PM

Anonymous said: ↑

You are all crazy. I have been prescribed Bhetta and now Bydureon. The later is not a pleasant experience. Neither did anything for my numbers. You all really make me take a look at the people pushing these messages where I work. Sad.

Donna T
Click to expand...

Donna

Frankly, no one is here seeking your approval. What's really sad is that you feel inclined to go on an anonymous message board intended for a group other than yourself and make comments. Find something else to do. Best of luck!

Geraldo R.

Anonymous · Oct 12, 2012 at 9:54 AM

Anonymous said: ↑

lilly boy here.

This is a powerful tool for Novo to use if Bydureon ever does get approved, and only if it gets approved before other once weekly hit the market, judging by Lilly totally inept managment team, it probably will not.

Now for this drug in particular, this is great news, but if you understand GLP-1's the drug does not actually lower A1C's. It simply allows your body to lower A1C's based on the pancreatic functionality left, and other MoA's that in a normal person would naturally all work hand in hand to keep ones sugars in check. However these patients have diabetes, so whether its Bydureon or Victoza there is no active agent that is actually combating the Sugars in the body. Your built in mechanisms that you were born with does this, there is no insulin in these products.

What does that mean. That means these tests are good to market, but if a physician or endo takes the time to truly dig deep, he would ask, why did Victoza beat Bydureon?

I wonder what line is Corporate gonna say should be the answer. It is clear why Victoza beat Byetta. Byetta has to be injected twice a day, and does not cover nightime highs or Lunch time. Thus when looking at a A1C, these uncovered periods impacts the overall avg a patient is experienceing, and results in a higher a1C than Victoza that has a full days coverage. Easy answer,

But when looking at the difference with once weekly, There will be a answer, but for the most part, They work the same and the next head to head could show the exact opposite. The actually drug would work exactly the same in a patients body as far as MOA, now there may be some difference in how the body removes the agents etc. But each are GLP-1, thus if you know the MOA you do know that the effectiveness of the drug is based on each individual patients remaining Pancreatic functionality, that is why many endo's pull a cpeptide test to see if GLP-ones would work any way.

So as your out there marketing this great news for Victoza, be prepared if a Endo wants to go deeper than the headlines and challenges the results.

Now with that being said, Victoza beat Bydureon and this can not be disputed. Regardless of anything, you all will have that fact. I think before you can have marketing pieces their has to be 2 tests or something like that at least that is what Lilly tells us the FDA requires. I beat Novo managment will have a marketing tools showing you all beat Byetta and Bydureon in two weeks...lol That is how aggressive your managment team is versus ours.

It is definately something if I worked for Novo i would make sure all of my doctor knew it, and leveraged Victoza more and more and more,,so that if Bydureon came out and had that same horrible delivery method, this head to head and the delivery method and the fact that Lilly has yet to outline what should a patient do if they came down with pancreatitus day 1-2-3-4...what should a patient do, since this will be in their body for a week.

No i dont work for the diabetes division anymore, so Yes i would definately be stating this to my endo's. Only thing is, that will be the question too for you to answer when your once a week comes out, as the pancreatitus issue is with all glp-1's.

I am glad in not selling Byetta or hoping to sell Bydureon. This drug just keeps getting bad news..
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Seriously, just once in your life… Just concede. There's no way you can possibly be married.

Reuters: Bydureon Falls Short of Victoza!

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