Layers and layers of management; no team inclusion or knowledge sharing; nothing done timely; CEO is checked out and clueless, along with senior management, some riding the gravy chain of old small company success and their financial gain, while being checked out completely, and letting true morons make costly decisions, as Senior Management isn't at work. A CEO blogs about his lovely family vacation and lay-offs in his same internal all employee message, along with instructions to IT and Sales they can't take a vacation - Mind Blowing Disfunction at its best!
Shire leadership has archaic ideas for growing business. Metrics, call averages, impulsive decisions. They bought some bio-techs (I was at one of them) and they have no idea how and why biological are different than pills/eye drops.