Amedica's Si3n4 great fit for Nuvasive

anonymous · Dec 27, 2018 at 10:44 PM

anonymous said: ↑

https://www.sciencedirect.com/science/article/pii/S1549963418300108
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Thirty-two patients were included in the study group. Mean age at surgery was 14.7 years. Preoperative and postoperative concentrations of serum titanium and niobium were significantly different (P = 0.0001). Median postoperative serum concentrations of titanium and niobium were elevated 2.4- and 5.9-fold above the normal range respectively with 95% and 99% of samples elevated postoperatively. A significant and rapid rise in serum titanium and niobium levels was observed within the first postoperative week, after which elevated serum levels persisted up to 12 months.

CONCLUSION:
We report abnormally elevated serum titanium and niobium levels in patients with titanium-based spinal instrumentation up to 12 months. The long-term systemic consequences of debris generated by wear and corrosion of spinal instrumentation is unclear but concerning, particularly as these implants inserted into the pediatric population may remain in situ for beyond 6 decades.
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correct link:

https://www.ncbi.nlm.nih.gov/pubmed/22996267

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Amedica's Si3n4 great fit for Nuvasive

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