I think it’s going to get approved

If it gets approved there will be a lot of monitoring. If pet scans not covered pets won’t pay it will cost too much. I was excited but no longer many doctors have their concerns.. this drug I once thought was good but now I’m concerned with what the true efficacy. Too much spinning the data and other drugs like this have failed. Need to start looking..what happened to biogen it’s not the same company.

 

Duh

 

Lots of drugs have been approved with unimpressive clinical efficacy data. Throw in bad safety data as well. This is no rarity so for anyone long in the chin and wanting Biogen to fail, you better wake up.

 

Most don’t want or think it should be approved, are hesitant to use if it is because of the serious side effects and believe it’s worth a fraction of the predicted price. That doesn’t sound like a recipe for success.

 

Serious adverse Aria was only 1.5% of all patients enrolled in both trials. That is peanuts, and while obviously requires monitoring to ensure this patient doesn't fall into that 1.5%, definitely overblown to think that Aria side effects are a limiting factor.
On efficacy trial showed ~20% improvement vs placebo in the positive trial, and in the negative trial same efficacy shown if patients got 8 or more infusions.
Ask yourself if your mother or father had Alzheimer's would you want to try for a 20% improvement or prefer to do nothing? Is 1.5% risk of serious Aria going to make you think twice or would you be comfortable with periodic MRI to monitor?
In the absence of any other option besides enrolling into a clinical trial, seems like an easy decison for families with loved ones.
Will the FDA think the same?

 

This is precisely why you did not get hired. This will require true sales people who know how to sell in a restrictive access environment. No sample droppers or caters. Again, that’s why you did not get hired.

 

Why are you on CP talking about clinical results for a non-approved product. Shut the fuck up. PLEASE!

 

So you're saying 20% chance that aducanumab offers a benefit compared to doing nothing along with a 1.5% risk of serious adverse event? Seems like greater than 10-to-1 benefit to risk profile, I would take those odds in Vegas.

 

Agreed. Soooooo many lame pharma reps who have never had to sell anything before.

 

And with ADU surely being denied in the next month or so, they will continue not selling anything - besides themselves in interviews looking for a new job

 

Omg so clever. I see what you did there.

 

again, you can’t sell period and it’s why you cry on here.

 

Never. Getting. Approved.

 

Post of the century.

Our HR department has cautioned us against Adu reps.

 

Dude you’re a leaky ass cushion.

 

Ooff....that’s a tough sell.

 

OMG save it. Such trash. The experts have basically stated it simply just means they possibly will last a bit longer in a long term care facility and nothing more. It may extend their unfortunate demise by a few months if lucky. So save your nauseating over the top message. You are only offering FALSE hope to so many and actually not amounting to really anything.

 

What? To sell something with very weak data that actually doesn't help patients and feel good about it?

 

Ok here’s to the 1-2 dolts who have wasted the past 6 months of their lives going off on Biogen on this site about Adu.

You zoom see on June 7 that this product will launch. Make no mistake, Adu is the most important launch in the history of Biogen. The company has deep pockets tontje time of 600 million to see this product will launch. Adu will be met with a very high demand from both neuro’s. and caregivers. Adu offers something that no other treatment options offer. That is it will reduce the cognitive decline cusses by the disease. There are over 600 specialists ready to use Adu.

I know those same 1-2 dolts we hate on this post but Biogen has the deep pockets to pull this off especially with so much riding on it. Sit back and enjoy your last few weeks of being wrong.

 

LOL thanks for the laugh idiot. 1-2 people? You've got to be crazy. Yes, we will "zoom" see. It doesn't matter how much of a deep pocket Biogen has, it isn't going to be approved you moron.