Also, One DM left a couple of months ago and a rep was promoted to DM. What business unit specifically are you asking about?
AZ has been a sh$tshow since the Repatha launch. Deanna was a nightmare who left for Bayer and Kim bailed to Sage with the two she brought to Amgen from Novo. Reps are better than the mgr.
Deanna O. was horrible! Heard she worse at Bayer, compliance queen, anyone who she doesn’t like or compete’s with gets ratted on. Glad she left they got her.
Why don’t you dummies by Amarin for Vascepa/Vazkepa? You guys can’t innovate and they can’t sell, plus it’s super cheap.
Amarin is worse than us, they cucked up their patents and now have generics flooding the market. Plus, they rigged their trials v mineral oil to inc event rate in PBO arm to make the benefit look greater. Dumb product.
You fail to recognize the Cherry Trial, the Jelis Trial, The Evaporate Trial to name a few! The Cherry Trial and Jelis Trial studied patients on pure EPA both showed a CV risk reduction in patients! Proving there is a difference between the 2 Omega 3’s. There is a difference between EPA and DHA and it’s effect on endothelial tissue. The patients in the Jelis Trial were Japanese patients (already ate a high level of fish which contains EPA and DHA) but added only a 1.8 gram dose of pure EPA and it showed a 19% in CV risk reduction. The Evaporate Trial was a mechanistic study. It looked at what Vascepa was doing to get the CV risk reduction. Pure EPA basically “evaporated plaque” strengthened endothelial tissue etc. Remember DHA can raise LDL cholesterol! Hence can increase CV risk. The FDA was the agency that approved mineral oil in the REDUCE-IT trial. The mineral oil in the study used was medical grade mineral oil not what you get in a Walmart. Remember the Jelis study did not have a placebo arm yet by adding a pure EPA at a 1.8 gram dose and not the higher of 4 grams in the REDUCE-IT showed a 19% reduction in CV events!! How do you explain that! Quit believing everything Amgen tells you or start looking at other studies correctly!! Repatha had only a 15% reduction in CV events but didn’t hit all the endpoints in a 5 point MACE and at very high cost compared to Vascepa. Just because Vascepa isn’t a “sexy drug” like Repatha don’t poo poo the science! Besides, the FDA does NOT approve a drug where the trial is “rigged”. By the way, you show your true intelligence by saying “dumb product”.
okay there current or former Vascepa rep. You have clearly outed yourself. If you truly were a REAL Repatha Rep, you would understand that repatha’s trial stopped MUCH earlier than any other CV outcomes trial in the lipid market because the patient type studied accumulated a pre-specifies number of events that ended the trial early and thus the data was read out after 2.2 years... how long did REDUCE IT take? Oh yeah, OVER 5 years.... even long that Lipitor’s TNT trial that took 5 years to show a 22% Risk reduction between Atorvastatin 10mg v 80mg while Repatha delivered that supposedly low 15% reduction in a median of only a 2.2 year time frame, faster CV benefit than any other non-statin on the market by far... If you actually knew your crap as well as you think you do, you would know on TIMI.org Repatha BLOWS Vascepa out of the water when you look at reductions in 2nd, 3rd, & 4th or more events, like 40%. Just like the piece y’all have carried around since REDUCE-IT... Repatha continues a long history of continuing to prove that lower LDL leads to improved cardiovascular outcomes and reduced CV risk... all Vascepa has is one trial that contradicts a long list of failures in the triglyceride product market... but yeah, it’s totally not Vascepa or Amarin’s fault... it’s definitely not smoke and mirrors... coming from the company that totally forgot to protect their intellectual property with patents... yeah let me just sell you this snake oil over here too while I’m at it... how many millions will you buy Mr. Know it all??? See, I can sell BS too, it’s easy...
And you can’t fucking show a reduction in CV events without a placebo arm you jackass... there is no control group to compare to so you can’t show a benefit v nothing?? You may be able to read the discussion session of a trial but you are far from being able to understand the majority of what they’re saying... hence your obsessive use of your “quotation marks”
And you can’t show a benefit if there is no placebo arm you Jack... if there is no control group there is nothing to compare the perceived benefit to so you are just drawing aimless conclusions... How is that for explaining things?? You may be able to read the discussion portion of a clinical trial but you are far from being able to understand it. Hence your obsessive use of “quotation marks” in your comments. Because you don’t have any original thoughts, just regurgitated kool-Aid from Amarin
