Last May, Acella Pharmaceuticals pulled 13 lots of its prescription hypothyroidism med NP Thyroid in the U.S. after testing revealed an excess of one of the drug's main ingredients. Now, the company is facing the opposite problem.
Acella is recalling certain lots of five separate doses of NP Thyroid after routine testing showed the batches weren't potent enough. Specifically, the product in the suspect lots contains less than 90% of the labeled amount of liothyronine and (or) levothyroxine, the drug's active pharmaceutical ingredients (APIs), the company said in a notice posted on the FDA's website. Dozens of cases of "serious" side effects could be related to the potency issue.