savvy

Re: No wonder Sands called LX1032

There are crooks at Lexicon. Given the recent press release on LX6171, it seems to be an appropriate time to talk about one of them, the head of the neuroscience research (abbreviated as HNR).

Per sources familiar with Lexicon affairs, HNR had troubles with school throughout his youth but miraculously managed to get a PhD degree. In his employment history, he was laid off from nearly every job he ever took including the one prior to his recruitment to Lexicon as a director. He got promoted to VP by selling programs such as LX6171.

Given the level of his IQ, it is no surprise that HNR is extremely insecure person. He got rid of all the guys around him who are apparently much smarter than he and surrounded himself with a group of girls. Some of the girls are intelligent and competent and some are not. Intelligent or not, it is a lot more fun to be with girls like ‘chatting’ behind the closed door and traveling together, etc. He and one of his female reports fabricated data on LX6171 in order to advance their own career at Lexicon (there were other instances like this that would take too much time to list them all here). The sad part was that Lexicon management was informed of the fraud but pretended that they did not know. In addition, LX6171 had the same effect on both wild-type and knockout mice, which means that it was nonspecific side effect and had nothing to do with the intended target. They also knew that LX6171 was insoluble and could not get into the brain. The insolubility was the reason they could not make it as pills (small enough for swallowing) and had to mix it with oil for trial subjects to drink. Having Known all that, they still pushed it into clinical trials so that they could report it to Wall Street and collect bonuses. Apparently, they did not tell Symphony all these. LX6171 was pitched to BMS many times. BMS scientists apparently were more savvy than those at Symphony.

Under the leadership of HNR, it is no wonder that the neuroscience alliance with BMS is getting no where. All those previous announced ‘amazing’ programs are already dead. If the management still have some common sense and want to save the company, it is time to get rid of those crooks.

 

Re: No wonder Sands called LX1032 16-Dec-08 03:20 am