Originally Posted by Anonymous
LDL = 35% reduction
ie. if patient attempting to get to 70 LDL, that means they need to be no more than approximately 100-105 LDL before getting the drug. Too many big macs and biggie fries will keep this from ever coming to fruition!
I am talking about outcomes not LDL reduction-- reduction in MI, all-cause mortality etc... the things that really matter. The Pravastatin studies used 40mg. if you want to chase LDL numbers you can always increase the dose.
FYI- I have no ties to any of the statin drugs.
Crestor is good at lowering LDL. However, the inherent problem with the drug is not the drug itself, but that there is no outcome data for it.