Stay Away from Diadexfucks

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Amazing that this dog gets any play at all on this board. When I asked about salesforce turnover, they balked and delayed. So I pushed it and dug deeper to get some answers. I'm glad I did, because it made it very easy to turn down the job. Every original Regional Account Manager (that's what they call their reps) is gone and the average tenure is now like 6 to 8 months (it actually sounded to me like 150% or more in turnover); they lost their original Chief Medical Officer; they lost two thirds of their original Medical Science Liasons; they lost their Reimbursement Director (and apparently never even replaced the job); they've fired two National Sales Managers; they lost their Marketing Manager; they lost all but one of their original Marketing Staff; they lost their original Chief Operations Guy; they lost their National Training Manager (which is why they are posting for one on their website); they laid off an entire lab division,... That was enough for me. I'm not throwing away my $140K/year job for those odds. Do your homework, people!! Their biggest potential lab distributer is Quest - and the folks at Quest I talked to (marketing dept and some field sales reps) don't like the PLAC2 and are told by their managers not to sell it. They also say the reimbursement situation is bad and the reps they know are pretty desparate to get orders. I also talked to some of my cardiologists and they've never heard of it. Most of them don't even write crp, so why would they use the PLAC2, which costs a ton more? I guess the only viable strategy in joining them is to wait out the storm until they get bought out? No thanks. But good luck to those of you who decided to make the leap of faith,...
 




Anonymous said:
Amazing that this dog gets any play at all on this board. When I asked about salesforce turnover, they balked and delayed. So I pushed it and dug deeper to get some answers. I'm glad I did, because it made it very easy to turn down the job. Every original Regional Account Manager (that's what they call their reps) is gone and the average tenure is now like 6 to 8 months (it actually sounded to me like 150% or more in turnover); they lost their original Chief Medical Officer; they lost two thirds of their original Medical Science Liasons; they lost their Reimbursement Director (and apparently never even replaced the job); they've fired two National Sales Managers; they lost their Marketing Manager; they lost all but one of their original Marketing Staff; they lost their original Chief Operations Guy; they lost their National Training Manager (which is why they are posting for one on their website); they laid off an entire lab division,... That was enough for me. I'm not throwing away my $140K/year job for those odds. Do your homework, people!! Their biggest potential lab distributer is Quest - and the folks at Quest I talked to (marketing dept and some field sales reps) don't like the PLAC2 and are told by their managers not to sell it. They also say the reimbursement situation is bad and the reps they know are pretty desparate to get orders. I also talked to some of my cardiologists and they've never heard of it. Most of them don't even write crp, so why would they use the PLAC2, which costs a ton more? I guess the only viable strategy in joining them is to wait out the storm until they get bought out? No thanks. But good luck to those of you who decided to make the leap of faith,...
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One is desperate that's for sure. Stabbed me in the back over a potential loss of part of her territory when I showed interest in working for the company. And I helped her get the job. Go figure. Money brings out the worst in people. The science behind PLAC 2 is very good. HS CRP is a crap test because it still picks up on inflammation everywhere in the body. PLAC 2 is more cardiac specific. But the treatment is the same as for any high risk patient. Statin and Niaspan lower PLAC 2 better than anything. It would help convince the doctors to use combo therapy using Niaspan. The fact the cards don't know about it doesn't mean anything other than they still continue to NOT keep up on the data. I first heard about PLAC2 three years ago. Why haven't they heard? They aren't reading. Too busy fixing the disease in the cath lab after the fact.
 


Anonymous said:
One is desperate that's for sure. Stabbed me in the back over a potential loss of part of her territory when I showed interest in working for the company. And I helped her get the job. Go figure. Money brings out the worst in people. The science behind PLAC 2 is very good. HS CRP is a crap test because it still picks up on inflammation everywhere in the body. PLAC 2 is more cardiac specific. But the treatment is the same as for any high risk patient. Statin and Niaspan lower PLAC 2 better than anything. It would help convince the doctors to use combo therapy using Niaspan. The fact the cards don't know about it doesn't mean anything other than they still continue to NOT keep up on the data. I first heard about PLAC2 three years ago. Why haven't they heard? They aren't reading. Too busy fixing the disease in the cath lab after the fact.
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Hey, Einstein. Riddle me this: has a prospective study ever been completed showing that pts randomized on the basis of a particular inflammatory marker being elevated at baseline, who then have had that marker specifically lowered with some therapy, have a lower CVD risk vs any comparator????

Ugh, I believe the answer is NO!

Nice try, but please stop pretending to be a scientist and accept the fact that you are a layperson who happens to sell something to medical customers.
 




Anonymous said:
Hey, Einstein. Riddle me this: has a prospective study ever been completed showing that pts randomized on the basis of a particular inflammatory marker being elevated at baseline, who then have had that marker specifically lowered with some therapy, have a lower CVD risk vs any comparator????

Ugh, I believe the answer is NO!

Nice try, but please stop pretending to be a scientist and accept the fact that you are a layperson who happens to sell something to medical customers.
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It's an inflammatory process that eats away at the fibrous cap holding the plaque against the artery wall. Why do you think aspirin is prescribed daily to prevent heart attack and stroke? Duh. I will take a not so big leap of faith to prevent a heart attack or stroke. You're an idiot. Now they are saying, based on studies, that 81mg of aspirin isn't enough that we should be taking 325mg because the inflammatory process is such a strong predictor. That was rolled out at the ACC in March.
 


Anonymous said:
It's an inflammatory process that eats away at the fibrous cap holding the plaque against the artery wall. Why do you think aspirin is prescribed daily to prevent heart attack and stroke? Duh. I will take a not so big leap of faith to prevent a heart attack or stroke. You're an idiot. Now they are saying, based on studies, that 81mg of aspirin isn't enough that we should be taking 325mg because the inflammatory process is such a strong predictor. That was rolled out at the ACC in March.
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Wow - what a moron you are! There is a HUGE difference between a predictor and a cause. Please take note: aspirin works primarily as an antiplatelet agent (i.e. it prevents clot formation). Does it have other effects? Sure it does, but take away the antithrombotic effects and it does nothing! Inflammatory markers do contribute to the process, but counteracting them is not essential in preventing CHD events.

Your comments are uninformed, and clearly the result of a layperson being fed snippets of scientific information.
 


Anonymous said:
Wow - what a moron you are! There is a HUGE difference between a predictor and a cause. Please take note: aspirin works primarily as an antiplatelet agent (i.e. it prevents clot formation). Does it have other effects? Sure it does, but take away the antithrombotic effects and it does nothing! Inflammatory markers do contribute to the process, but counteracting them is not essential in preventing CHD events.

Your comments are uninformed, and clearly the result of a layperson being fed snippets of scientific information.
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Yeah...what he said!! I can add to it. ARISE with an antiinflammatory drug also failed. I have heard that the Cox-2 drugs and antibiotics also reduce inflammation alot, but they do not prevent CV events in clinical trials.

PLAC is whack!
 


Anonymous said:
Wow - what a moron you are! There is a HUGE difference between a predictor and a cause. Please take note: aspirin works primarily as an antiplatelet agent (i.e. it prevents clot formation). Does it have other effects? Sure it does, but take away the antithrombotic effects and it does nothing! Inflammatory markers do contribute to the process, but counteracting them is not essential in preventing CHD events.

Your comments are uninformed, and clearly the result of a layperson being fed snippets of scientific information.
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What is your proof source that counteracting the inflammatory process does not prevent heart attacks?
 


Anonymous said:
Wow - what a moron you are! There is a HUGE difference between a predictor and a cause. Please take note: aspirin works primarily as an antiplatelet agent (i.e. it prevents clot formation). Does it have other effects? Sure it does, but take away the antithrombotic effects and it does nothing! Inflammatory markers do contribute to the process, but counteracting them is not essential in preventing CHD events.

Your comments are uninformed, and clearly the result of a layperson being fed snippets of scientific information.
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Ask any of your cards. Preventing platelet aggregation is not the only reason ASA is prescribed. Once the inflammatory process eats away at the fibrous cap, the plaque ruptures and a heart attack occurs. ASA is also prescribed to help prevent this. I don't work for Diadexus. I had a long conversation with Superko when I was considering going to work for Diadexus. He says the science behind PLAC 2 is very sound. Why I didn't pursue the opportunity further was that I had the golden handcuffs on at Kos. I'm glad I stayed and cashed out big. Also, the turnover at Diadexus is as bad as a previous post stated. If you don't grow quarter over quarter EVERY quarter, you're gone. They chew em up and spit them out over there.
 


Rule #1: Never attempt to argue science with nonscientists. They only believe what they hear or are told by others as long as it is consistent with their previous beliefs.

Rule #2: 99.9% of the posters/readers of CP are sales people, and are nonscientists. This includes the nurseys who become salespeople. As such, they do not understand the basic tenets of the scientific process, evidence, and the difference between proof and conjecture.

Rule #3: Apparently, most sales people have trouble reading, interpreting, and understanding the English language. Even if you write something that is clear, Rules #1 and #2 come into play and all is lost.
 


Anonymous said:
Rule #1: Never attempt to argue science with nonscientists. They only believe what they hear or are told by others as long as it is consistent with their previous beliefs.

Rule #2: 99.9% of the posters/readers of CP are sales people, and are nonscientists. This includes the nurseys who become salespeople. As such, they do not understand the basic tenets of the scientific process, evidence, and the difference between proof and conjecture.

Rule #3: Apparently, most sales people have trouble reading, interpreting, and understanding the English language. Even if you write something that is clear, Rules #1 and #2 come into play and all is lost.
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Rule #4 If we always wait for evidence based medicine, we'd all be dead. LOL
You non-scientist!!!!!!!!!!!!!!
 


Anonymous said:
Rule #1: Never attempt to argue science with nonscientists. They only believe what they hear or are told by others as long as it is consistent with their previous beliefs.

Rule #2: 99.9% of the posters/readers of CP are sales people, and are nonscientists. This includes the nurseys who become salespeople. As such, they do not understand the basic tenets of the scientific process, evidence, and the difference between proof and conjecture.

Rule #3: Apparently, most sales people have trouble reading, interpreting, and understanding the English language. Even if you write something that is clear, Rules #1 and #2 come into play and all is lost.
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And what do you say to those terminally ill cancer patients who want to get their hands on the latest drugs that are not approved quite yet because we don't have all the evidence completely tied up in a neat little package like you describe. You are narrow minded. I hope you never have a loved one with cancer that can't get the latest and the greatest because it is still in phase 3, and even though it looks to be really safe and effective, the patient will die before they get it. And you are the biggest scientist wanna be I've ever seen post on CP. You are an arrogant ass.
 


Anonymous said:
Rule #1: Never attempt to argue science with nonscientists. They only believe what they hear or are told by others as long as it is consistent with their previous beliefs.

Rule #2: 99.9% of the posters/readers of CP are sales people, and are nonscientists. This includes the nurseys who become salespeople. As such, they do not understand the basic tenets of the scientific process, evidence, and the difference between proof and conjecture.

Rule #3: Apparently, most sales people have trouble reading, interpreting, and understanding the English language. Even if you write something that is clear, Rules #1 and #2 come into play and all is lost.
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It's a tough choice, but I gotta go with Superko over you.
 








Anonymous said:
Thanks for the compliment. I know I may not have all the numbers exactly right, but they are close enough to make my point. i dare the other poster who keeps calling me an idiot to post what are his/her numbers and convince me how this test is going to make so many people so much money.

Good sell people can sell anything, but it's much easier and better if what they sell is a good product with a real need. Nothing I have seen yet tells me there's a great need for this.
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High quality people?? My ass!!! They would sell their mothers for a buck! bottom line is this...is the test covered by managed care??? Nope!! And, is it any better at "predicting" heart disease than a HSCRP test?? Nope again!! And many ins co's are not covering HS CRP anymore either! Look...anything that is new and/or innovoative is not the question here...the question is...will ins pay for the test!! Ins co's will not pay...patients will not pay out of pocket, and the dr's don't want it in their office either because that brings in a whole different can of worms...the state!! Who will need to do inspecitions, etc. If the doc's still have labs in their offices, they may be willing to promote the test (for a measly 45 bucks). But, then again...how many dr's still have labs in their offices?? Not many in my metropolitan area. And all the po-dunk areas are not big enough to make the huge quotas! I was asked to join right after we were bought out. I opted to stay and see if I got severed. I didn't, but, I wouldn't go sell that test now anyway. Wouldn't have earlier, won't now. I just don't trust all those "high" performers from Kos....we who worked at Kos know that the high performers were the ones who knew how to scam, cheat and steal. Only a very samll percentage were not scammers. GR & JM were hard working and had a great "system".. TH & his female coat tail rider knew how to "buy" their way to the top and they were the biggest cry babies whenever our comp plan went to growth instead of volume. Says it all!!! Oh well.... Kos is dead...too bad for all the High Performers!! Now they all have to "work"!!!!!!!!!!!!!!!!!! hahahahahaha.....!!!!!!!!!!!!!!
 


Anonymous said:
High quality people?? My ass!!! They would sell their mothers for a buck! bottom line is this...is the test covered by managed care??? Nope!! And, is it any better at "predicting" heart disease than a HSCRP test?? Nope again!! And many ins co's are not covering HS CRP anymore either! Look...anything that is new and/or innovoative is not the question here...the question is...will ins pay for the test!! Ins co's will not pay...patients will not pay out of pocket, and the dr's don't want it in their office either because that brings in a whole different can of worms...the state!! Who will need to do inspecitions, etc. If the doc's still have labs in their offices, they may be willing to promote the test (for a measly 45 bucks). But, then again...how many dr's still have labs in their offices?? Not many in my metropolitan area. And all the po-dunk areas are not big enough to make the huge quotas! I was asked to join right after we were bought out. I opted to stay and see if I got severed. I didn't, but, I wouldn't go sell that test now anyway. Wouldn't have earlier, won't now. I just don't trust all those "high" performers from Kos....we who worked at Kos know that the high performers were the ones who knew how to scam, cheat and steal. Only a very samll percentage were not scammers. GR & JM were hard working and had a great "system".. TH & his female coat tail rider knew how to "buy" their way to the top and they were the biggest cry babies whenever our comp plan went to growth instead of volume. Says it all!!! Oh well.... Kos is dead...too bad for all the High Performers!! Now they all have to "work"!!!!!!!!!!!!!!!!!! hahahahahaha.....!!!!!!!!!!!!!!
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Spoken like a true Non Performer! You expose yourseelf for the failure you are. All the performers cheated. Thanks for the laugh. I am certain you were not asked as only 2-25 went another way. Folks like you were not asked. We have a pool of candidates in waiting for areas all over.

I heard a pretty good quote and how it fits into sales the other day. If I could only have 1 of the 2 I would take a great sales team over a great sales product. Point in case, the late years at KOS when the quality was watered down with weaklings and Upper Management manged to balance arrogance with ignorance perfectly. " A losing recipe" Great product stopped performing.

Early days KOS great people with great product= great growth and opportunity for many.

Early days for DDX- Transitioning from Science to Sales Stage right now. Great test that adds value and great team. Not just a marker of inflammation but a maker of inflammation. You really do not understand the market on ACS and Stroke. 16 poster presentations this year at AHA and ACC. I guess their is no interest.

At least if we didn't take you because you are weak, you can buy it post IPO and ride our coattails again. Most of us are used to lugging along passengers and leetches, so its not a problem.

Thanks for the laugh.
 



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