BIG MOVE -- AZ partners with Amgen


Anonymous

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Folks,

This is the kind of move (and hope) we've all been waiting for --- AZ has announced a partnership with Amgen. This move will hopefully yield some great biologics and drugs that require skilled salespeople (skills beyond the scope of a half-r***** contract team). We need this deal to pay dividends. Keep your fingers crossed.
 




True. They are partnering on 5 new drugs for inflammatory diseases such as asthma, lupus, psoriasis. They are hoping the drugs will hit market in 2014 and profits will be split between two companies. AZ is making upfront payment for opportunity on these.

This is bad news for all the AZ haters on this forum. Let the bashing begin about how AZ will screw this up.
 






Folks,

This is the kind of move (and hope) we've all been waiting for --- AZ has announced a partnership with Amgen. This move will hopefully yield some great biologics and drugs that require skilled salespeople (skills beyond the scope of a half-r***** contract team). We need this deal to pay dividends. Keep your fingers crossed.
You should ask the Amgen people how they would view this. Amgen has many ex AZ people who were good enough to win a job at Amgen and leave this shithole. They were running away from AZ not running toward Amgen. Their sales force views us as a bunch of glorified caterers who couldn't have a scientific discussion on a disease state with a teleprompter. If this happens then you had better hope you are among the best in product and disease state knowledge because you are going to be compared to their sales force.
You may be a big frog in this cesspool but you will be a toad with warts in theirs.
 


You should ask the Amgen people how they would view this. Amgen has many ex AZ people who were good enough to win a job at Amgen and leave this shithole. They were running away from AZ not running toward Amgen. Their sales force views us as a bunch of glorified caterers who couldn't have a scientific discussion on a disease state with a teleprompter. If this happens then you had better hope you are among the best in product and disease state knowledge because you are going to be compared to their sales force.
You may be a big frog in this cesspool but you will be a toad with warts in theirs.

Ha Ha.

As AZ moves to pro sales people. (See success of specialty sales forces) sample dropping bagel bearers such as your self will be hustling blow jobs at the bus station.

Har.
 


A $50M deal is basically chump change. This is just another "what if" investment venture, that if it pays dividends, won't be anytime soon. We just want access their their stock-in-trade, and nothing more. This is just another roll of the dice, and not something that will have a major impact. Nothing really to crow about.
 


Sorry, can't get excited on this one. AZ is moving more to an in-licensing partnership model to bring drugs to market and their picks over the last few years have given us a lot more duds than winners. Just because these 5 drugs-in-development are from Amgen doesn't mean anything. There are several other in-licensed drugs also in development, but I just don't see anything really positive. It's just business as usual.
 


A $50M deal is basically chump change. This is just another "what if" investment venture, that if it pays dividends, won't be anytime soon. We just want access their their stock-in-trade, and nothing more. This is just another roll of the dice, and not something that will have a major impact. Nothing really to crow about.

True, 50 mil would be but a sneeze compared to the amount paid in fines for Seroquel alone. Probably doesn't pay the amount of money to CYA on the CIA(s).
 


Folks,

This is the kind of move (and hope) we've all been waiting for --- AZ has announced a partnership with Amgen. This move will hopefully yield some great biologics and drugs that require skilled salespeople (skills beyond the scope of a half-r***** contract team). We need this deal to pay dividends. Keep your fingers crossed.

Hey assclown,you are one layoff away from being a member of a half-r***** contract team!That's all the difference there is swipe!!!
 


You should ask the Amgen people how they would view this. Amgen has many ex AZ people who were good enough to win a job at Amgen and leave this shithole. They were running away from AZ not running toward Amgen. Their sales force views us as a bunch of glorified caterers who couldn't have a scientific discussion on a disease state with a teleprompter. If this happens then you had better hope you are among the best in product and disease state knowledge because you are going to be compared to their sales force.
You may be a big frog in this cesspool but you will be a toad with warts in theirs.

You give Amgen personnel far too much credit!
 


Why would Amgen be willing to share the profit from 5 high potential drugs? They wouldn't is the answer. These 5 are either long shots or limited potential market products that Amgen wants help with in the funding of their development. 50 million is just the entry fee, the real cost is in development funding. If even one of these 5 projects ever comes through it will be very lucky. This is just eyewash for Wall Street to think that there is still something to hope for in the pipeline.
The real question to answer is why doesn't MedImmune have 5 decent projects worth funding?
 


Why would Amgen be willing to share the profit from 5 high potential drugs? They wouldn't is the answer. These 5 are either long shots or limited potential market products that Amgen wants help with in the funding of their development. 50 million is just the entry fee, the real cost is in development funding. If even one of these 5 projects ever comes through it will be very lucky. This is just eyewash for Wall Street to think that there is still something to hope for in the pipeline.
The real question to answer is why doesn't MedImmune have 5 decent projects worth funding?

WOW, you people on here are negative.

If you read the article, you would have noted that the deal was for $50 million up-front, followed by AZ assuming 65% of the burden for development of the drugs for a set period of time. After that period has expired the split in development costs will be 50/50, followed by Amgen getting sole financial benefit from the drugs at the outset. Finally, in the end, the two companies will share the profits of the drugs.

Important to note also is the fact that Amgen was driven to make this deal because of MedImmune. That's right! Medimmune was actually an asset for AZ!!! These drugs are close, they just need to be pushed over the goalline, and based on the articles, it looks like a collaborative effort between MedImmune and Amgen will do that.

Where does the traditional AstraZeneca sales force come into play? Well these are innovative therapies that could potentially apply to millions of patients. A large salesforce is going to be needed to sell these drugs.

Look, I get it. It is the cool thing to be all doom and gloom these days at AZ. But if you read the article objectively, there is definitely reason for optimism.

And, finally, AZ has a shit-ton more cash where that came from. They can afford to make some aggressive plays and try and shift the trajectory of where we're headed.

Again, keep your fingers crossed and lets hope for the best with these drugs.
 


And with AZ stellar track record of bringing drugs to market it should only take 2 or 4 years??? Mean while we make one more stock buy back during the falling profits because of the generics and AZ is toast as far (as cash goes ). AZ has nothing and Amgen has a new life!

AZ is laying off 15% of the home office. You can bet your ass after this layoff there will be nobody left but a couple of marketing clowns and all the SSLT. Gloom and Doom. Nope, not me, why should I worry that 30,000 people have been laid off while our leader has had an increase in salary to 12,000,000.00 a year.

Everything is SOP!
 


And with AZ stellar track record of bringing drugs to market it should only take 2 or 4 years??? Mean while we make one more stock buy back during the falling profits because of the generics and AZ is toast as far (as cash goes ). AZ has nothing and Amgen has a new life!

AZ is laying off 15% of the home office. You can bet your ass after this layoff there will be nobody left but a couple of marketing clowns and all the SSLT. Gloom and Doom. Nope, not me, why should I worry that 30,000 people have been laid off while our leader has had an increase in salary to 12,000,000.00 a year.

Everything is SOP!
Indeed, AZ lays off 30,000 and counting to save money that they can use to jack up their stock option values and to transfer $50 million to our competitors which is another attempt to stablize the falling stock values. The real question should be, where are our new products that get listed every year but never seem to make it to market? If we cannot develop our own products then we are nothing more than a sales force gone begging for someone to take our entry fee and let us play a bit longer. Ask the people at Medimmune what they think of AZ leadership. Who will want to partner with us when our corporate offices have been turned into assisted living apartments?
 


WOW, you people on here are negative.

Important to note also is the fact that Amgen was driven to make this deal because of MedImmune. That's right! Medimmune was actually an asset for AZ!!! These drugs are close, they just need to be pushed over the goalline, and based on the articles, it looks like a collaborative effort between MedImmune and Amgen will do that.

The "asset" that MedImmune is providing here is unused development capacity, since they have nothing in their own pipeline that can keep those facilities busy.

Since you accuse us of negativity, I'll be real optimistic and say that one of these developmental drugs will turn out to be cash positive in five years time.
 


Big Pharma Buys Access to This Promising Biotech Pipeline
By Brian Orelli
April 3, 2012

Given its size, when you think of Amgen (Nasdaq: AMGN ) , you usually think of a licensee, rather than licensor, but the big biotech was the latter times five yesterday when it struck a deal with AstraZeneca (NYSE: AZN ) .

The deal makes the two companies 50-50 partners on five Amgen-developed drugs to treat different types of inflammation -- well, almost 50-50. AstraZeneca has to pay $50 million and 65% of the development costs through 2014 to get in on the deal, but after that it will go down to an evenly split cost structure. Profits will be shared 50-50, but only after Amgen takes a royalty cut in the low single digits for one drug and mid-single digits for the other drugs.

The five drugs are all antibody-based drugs targeting different proteins involved in inflammation, which affects everything from psoriasis to asthma to Crohn's disease. The furthest along, brodalumab, is battling it out with Eli Lilly's (NYSE: LLY ) ixekizumab, and Amgen plans to start a phase-three trial in psoriasis shortly. The other four are all in phase-one development.

Why would Amgen want to give up the upside from five drugs? Because it doesn't have to pay for the full downside should one or more of the drugs fail. By reducing its costs, Amgen can diversify, spending the money elsewhere on its pipeline. It's not that much different from an investor owning more than one drugmaker.

And because AstraZeneca has expertise in respiratory and gastroenterology, there could be some cost savings if sales reps can hock AstraZeneca's products alongside the duo's drugs being developed for asthma and ulcerative colitis, a type of inflammatory bowel disease.
 


continued:

For AstraZeneca, the reason for the move is pretty clear. The $50 million payment is a small price to pay to help boost its paltry pipeline. Sure the profits aren't as high as if it had gone out and bought a small biotech with five drugs, but the cost and risks aren't as high, either.

Whether the move turns out to be a good one for Amgen depends largely on the success rate for the five drugs. If they all succeed -- unlikely, but certainly possible -- the deal will look like a waste of resources. But then, that's true of all unnecessary hedges, and doesn't necessarily make them bad moves.
 


Key sentence in that article:

"And because AstraZeneca has expertise in respiratory and gastroenterology, there could be some cost savings if sales reps can hock AstraZeneca's products alongside the duo's drugs being developed for asthma and ulcerative colitis, a type of inflammatory bowel disease."

Looks like new drugs are coming for AZ reps to "hock".
 



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