Bayer's drug beats Veozah to the hot-flash induced by breast cancer treatment indication

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Indeed, we are f... ed!

January 09, 2025
Not intended for UK Media

Elinzanetant meets all primary and secondary endpoints in Phase III study OASIS 4 for treatment of moderate to severe vasomotor symptoms caused by breast cancer treatments
In OASIS 4, a Phase III study conducted outside of the US, the investigational compound elinzanetant met all primary endpoints demonstrating a statistically significant reduction in frequency of moderate to severe vasomotor symptoms (VMS) caused by adjuvant endocrine therapy compared to placebo in women with or at high risk of developing hormone receptor positive breast cancer / The study also met all secondary endpoints with a reduction in severity of VMS at weeks 4 and 12, a reduction in frequency of VMS at week 1 as well as improvements in sleep disturbances and menopause related quality of life / The safety profile over 52 weeks is generally consistent with previously published data in postmenopausal women with VMS / Positive topline results from OASIS 4, the first pivotal international Phase III study addressing this population of unmet medical need, add to the positive results of OASIS 1,2 and 3 and further support the efficacy and safety of elinzanetant / Elinzanetant is the first dual neurokinin-1 and 3 (NK-1,3) receptor antagonist in development for the non-hormonal treatment of moderate to severe VMS associated with menopause or caused by adjuvant endocrine therapy, administered orally once daily
 








Can someone explain how one key leader in this mess came out smelling like a rose? How is D.B head of anything? Did his escapades to Canada come right in the nick of time to disassociate him from any accountability? Now the entire sales organization waits patiently for him to F everything else up. What is his job exactly anyway as Head of sales? What does he do?
 
























The bigger issue is that women’s health prescribers aren’t scared sh$tless of hormones anymore. Hormones are the answer for MOST Post-menopausal women. Hormones are cheap, they address ALL of the symptoms- of which dryness is probably the worst for most women- as well as the men in their lives. These products are late to the dance, and will never be blockbuster drugs. Veozah won’t even sniff $300 million after 3 years on the market. Bayer is gonna give their “me-too” away for several months to try to steal share, but that is not going to be a death blow to Veozah. Most women just flat don’t need these drugs, and most aren’t gonna pay a premium price for a partial solution to their symptoms. Astellas reps- you might have a year to find a new gig, and you might not. Don’t buy the BS from this senior leadership team. There is no long term future for the Veozah sales force.
 


anonymous said:
Can someone explain how one key leader in this mess came out smelling like a rose? How is D.B head of anything? Did his escapades to Canada come right in the nick of time to disassociate him from any accountability? Now the entire sales organization waits patiently for him to F everything else up. What is his job exactly anyway as Head of sales? What does he do?
Click to expand...
DB was way over his waders 2 jobs ago. And he is currently just a figurehead.
 



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