Yes, an over dose of saltpeter can cause wiltering and a total disengagement of the member from the groin bone (yes, the groin bone is attached to the thigh bone, and so on). That is why an sIgE level for Spanish Fly is important in determining the amt. of saltpeter to be administered.
Make no mistake, there is no cross-reactivity between Spanish Fly, French Fly, Polish Fly and a number of other "Flys" that may share the same family but are antigenically much different. This also holds true for the American House Fly which has issues all of its own. That's why one cannot use anything but a true Spanish Fly ImmunoCAP.
Ole