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Top consideration is territory, territory, territory.  If you are in a city that is surrounded by many other loaded up teams, you are very vulnerable.  The obvious way to look at this is geography size per rep and the biz generated.  Even very high volume cities do not need alot of reps each covering a very small piece of turf.  If docs are fairly concentrated in area they only need a very small number of reps to adequately cover them. Look around you. The party is coming to an end soon.