Two of the pipeline programs, including PTC518 for Huntington, are on clinical hold and the company did not mention publicly. I tried complaining internally, but they don't care.
Two of the pipeline programs, including PTC518 for Huntington, are on clinical hold and the company did not mention publicly. I tried complaining internally, but they don't care.
many areas - clinical hold in the USA to a maximum dose of 5mg for PTC518 due to severe toxicity in animals, e.g. irreversible nerve damage in monkeys, and genotoxicity. Trial is stopped in the US without any plans or potential to start again
- undisclosed clinical hold with aadc in the US earlier this year
- clear issues with the ataluren FDA discussions, not what we said in the press release, much more clear
basically many programs without a future in the US.
