The problem right now and most empirically shown is the number of offices, hospitals, and health systems which are limiting or eliminating access to physicians, hospitals, or prohibiting the use of sampling, which is the primary reason pharmaceutical reps are able to do their job.
Unless an analyst can provide strong evidence to physicians and health administrators as well as pharmaceutical company executives, it's going to be harder and harder for the latter to justify several thousand rep sales forces and the overhead that goes with it ... perhaps Obamacare helped the pharmaceutical industry in the short run, but in the long run, when something has to be cut, an overloaded and high selling cost industry is going to take the hit.
Unfortunately, pharmaceutical sales reps are going the way of buggy-whip salesmen. But the damage was probably as self-inflicted as anything that killed it.