Cobenfy Launch

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anonymous said:
You haven’t had a single issue with what? Docs can’t write it and those that have tried it aren’t impressed. I hope I can hang on for a year.
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Warning to all those leaving the company and who are misrepresenting or sharing proprietary informations. Customers that you think are your friends are reporting back and legal ramifications are mounting. Remember all the documents you signed when you joined.
 




anonymous said:
Warning to all those leaving the company and who are misrepresenting or sharing proprietary informations. Customers that you think are your friends are reporting back and legal ramifications are mounting. Remember all the documents you signed when you joined.
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Feedback from providers that the drug simply doesn’t work is not proprietary info. Neither is the fact that nobody can get it covered.
 




anonymous said:

Colossal failure… wait until details get out, there will be a white paper about us….Someone is going to loose their job over this!​

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Very concerning study results, is this drug a dud?

Efficacy and Safety of Xanomeline-Trospium Chloride in Schizophrenia: A Randomized Clinical Trial - PubMed

First, the sample in this trial is different from most antipsychotic studies because African Americans make up 60% of the participants. Typically, this group is under-represented in clinical trials, so this could make comparisons to other studies a bit trickier.

Also, all the patients were inpatient for the full 5 weeks of the trial and had to voluntarily agree to stay for that long. If they chose to leave, they were dropped from the study. This could introduce some bias, since people who agree to stay in a hospital setting for 5 weeks may not be representative of all patients with the condition.

When it comes to the results, patients on placebo had a 12-point reduction on the PANSS scale just from being in the hospital, while those on Cobenfy had a 20-point reduction. The 8-point difference between the two groups doesn’t seem huge, especially considering that other drugs like Olanzapine showed a 16-point reduction and Clozapine showed a 22-point reduction in similar studies.
 








anonymous said:
Didn't you check out the company first? Shouldn't have been a surprise.
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Reviews are coming in from patients. Doctors are hesitant to prescribe this drug over existing treatments.

“The side effects became unbearable. I was vomiting every morning and could barely eat more than 500 calories a day. In just two weeks, I lost around 13 pounds, but definitely not in a healthy way.

For now, I’ve gone back to my old medication.”
 


anonymous said:
Reviews are coming in from patients. Doctors are hesitant to prescribe this drug over existing treatments.

“The side effects became unbearable. I was vomiting every morning and could barely eat more than 500 calories a day. In just two weeks, I lost around 13 pounds, but definitely not in a healthy way.

For now, I’ve gone back to my old medication.”
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Total BS unless this patient was given a sample. Because no payors cover it.
 











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