Ok clueless, let me explain what I'm talking about. You idiots think all patients are the same, they progress at the same rate, show the same symptoms at the same time. There's alot of things that have to align to get our drug. Idiotic home office people want to think in terms of dividing patients into pure buckets of 1st, second, 3rd line. Go ask a doctor what he uses second line, if he's being honest he will tell you it depends.
What do the platelets look like, transfusion dependent,,, that information is important and it's different for every patient. Doctors think in terms of symptoms and that therapy may change based on such.