Si3N4


Smith and Nephews Redapt killed my TM business almost overnight. Had a tough hip case where the Doc called his partner in to help and he brought a new system in with him. I still got my liner cemented in their cup but my doc is making the switch anyways. Long story short it took one case and years of my TM business is gone. For those that aren't ready for this get ready, because TMs days of easy money are about to be gone for you to. If it isn't SN it is one of the other ones about to get ya.
Not as if there is only one company with titanium 3-D printing. If you are a ZB sales rep and resting on the laurels of TM, then please step aside for someone else keeping more tools in the toolbox. http://www.zimmerbiomet.com/medical-professionals/common/our-science/osseoti-porous-metal.html
 

material almost does not matter
Look at 20 year results of fiber metal, beaded, plasma sprayed, they are all up in high 90% when placed right for primaries
TM and the 3D printed are the current for revisions until the 2018-2019 Medicare reimbursements come about (MIPS), then those will only be used for extremely bad revisions
The extreme pressures of pay will be put on the dr so that either they won't do the revision or use a basic primary cup and it will be backed up by 20 year data (TM will have the data but no one will pay the premium , all about the new pay structures. Why would you put in something more expensive when it will come directly out of your own pocket )
The industry is in for big change
It is going to be weird times coming soon, very European
Unless they change the rules again as happened with CJR but how many times will instant about face be tolerated. That costs too much money for all the care providers to switch up
The "man" is forcing single payer, govt care. Ramble ramble
 
I get that health system rather pay less but at what cost? That means PEEK implants which from what ive read do not fuse well due to fiburous tissue that often surrounds implants (spine implants). Not to mention peek has more issues with infections. Infections cost US heslthcare system 28-45 billion a year (includes all types surgies). PEEK also has a higher revision percentage due to both the problem i already mentioned. Revisions = higher costs per patient overall. Logiclally doesnt make sense to chose an implant that may cost more upfront to save money in the longrun?

On a seperate note, all biomaterials degrade in the body over time. Metals, especially heavy build up in the body causing allergic responses and heavy metal poisoning. As PEEK degrades, pieces fleck off causing inflammation wherever they are in the body; body sees it as a foreign substance.

Si3N4 does not have these issues. Wouldnt that make it worth the premium cost? (not sure Si3N4 cost compared to other materials)
 
No, it wouldn't. Hospitals would see it as an unnecessary product to use with the cheaper options with similar results if not better results. Unfortunalty you are to late to the game unless price is cut 2/3rds.
 
Where have you been the last few months???
Trabecular metal is about to be another short lived product. There are a few companies that have products coming out or allready out that have better results then TM. If you don't believe me just wait a few months. By the end of the year you will most likely see these products. 3D printing technology has come a long long way in a short time, and it's about to really mess that TM market up for you guys. Hope Zimmer is keeping you up to date on what to expect soon.


Short lived as in almost 20 years of clinical success? Id be interested in knowing which products have better results than TM? So there are products coming out in a few months that are already better than TM. You must be a product manager for one of these "great" products. Not saying there couldnt be better products coming down the pipeline, but TM is the gold standard for porous metal in orthopedics. Until these other products are out and have shown to be as good, docs will keep putting them in.
 
Short lived as in almost 20 years of clinical success? Id be interested in knowing which products have better results than TM? So there are products coming out in a few months that are already better than TM. You must be a product manager for one of these "great" products. Not saying there couldnt be better products coming down the pipeline, but TM is the gold standard for porous metal in orthopedics. Until these other products are out and have shown to be as good, docs will keep putting them in.

Your company not educating you is sad. Reality will bite you soon.
 
material almost does not matter
Look at 20 year results of fiber metal, beaded, plasma sprayed, they are all up in high 90% when placed right for primaries
TM and the 3D printed are the current for revisions until the 2018-2019 Medicare reimbursements come about (MIPS), then those will only be used for extremely bad revisions
The extreme pressures of pay will be put on the dr so that either they won't do the revision or use a basic primary cup and it will be backed up by 20 year data (TM will have the data but no one will pay the premium , all about the new pay structures. Why would you put in something more expensive when it will come directly out of your own pocket )
The industry is in for big change
It is going to be weird times coming soon, very European
Unless they change the rules again as happened with CJR but how many times will instant about face be tolerated. That costs too much money for all the care providers to switch up
The "man" is forcing single payer, govt care. Ramble ramble

What do you mean material doesnt matter? I can find many scientific publications showing the drawbacks of both PEEK, Titanium, CoCr, etc.. Two of the biggest issues is bacteria growth (which impacts bone on-growth) & toxic build up. I'm scratching my head at the claim of material not mattering. OH ya, PEEK is seen as a foreign substance in the body so our bodies respond by surrounding the implants with fibrous tissue.
 
The main reasons for revision of the retrieved porous tantalum implants were infection (35.5%, 44/124 components), instability (22.6%, 28/124) and loosening (17.7%, 22/124)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664095/

For a product that touts bone in-growth, instability & loosening is pretty high at ~40% of the patients requiring revision surgery.

Now imagine a material that has been clinically proven to have bone in-growth on par with autograft that is also anti-bacterial. That's just for its first generation. 2nd Generation Si3N4 improves on its osseoincorporation and antibacterial abilities.

My question is wouldn't Si3n4 be the perfect material to be used in place of TM for Ardis & Zimmer's Dental implants?
 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664095/

For a product that touts bone in-growth, instability & loosening is pretty high at ~40% of the patients requiring revision surgery.

Now imagine a material that has been clinically proven to have bone in-growth on par with autograft that is also anti-bacterial. That's just for its first generation. 2nd Generation Si3N4 improves on its osseoincorporation and antibacterial abilities.

My question is wouldn't Si3n4 be the perfect material to be used in place of TM for Ardis & Zimmer's Dental implants?


So that pretty much says use the cheaper implant. Guess Dorr & Hofmann got it right with CSTi? Too bad it was/is phased out. What is left of the Centerpulse technology except for the ultracongruent and the offset acetabular reamer? Another great acquisition for Zimmer, kind of like Biomet.
 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664095/

For a product that touts bone in-growth, instability & loosening is pretty high at ~40% of the patients requiring revision surgery.

Now imagine a material that has been clinically proven to have bone in-growth on par with autograft that is also anti-bacterial. That's just for its first generation. 2nd Generation Si3N4 improves on its osseoincorporation and antibacterial abilities.

My question is wouldn't Si3n4 be the perfect material to be used in place of TM for Ardis & Zimmer's Dental implants?

No, again, there are better and cheaper products. Just because nobody wants your Si$n4 you feel the need to bash other companies. Have you seen the comparison sheets from other companies? Do you even have one?
 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664095/

For a product that touts bone in-growth, instability & loosening is pretty high at ~40% of the patients requiring revision surgery.

Now imagine a material that has been clinically proven to have bone in-growth on par with autograft that is also anti-bacterial. That's just for its first generation. 2nd Generation Si3N4 improves on its osseoincorporation and antibacterial abilities.

My question is wouldn't Si3n4 be the perfect material to be used in place of TM for Ardis & Zimmer's Dental implants?

You do realize that instability really has nothing to do with the ingrowth of the product.
 
The mean operative times for both the ring and block device groups were slightly lower than the control treatment. Two patients in the block treatment group were determined to be nonunion between the 6- and 12-month time points and underwent additional surgery. Five patients with porous tantalum devices showed radiographic evidence of device fragmentation, and one patient in addition had radiographic evidence of erosion of the involved vertebral bodies by the device. One patient in the ring treatment group died from a myocardial infarction and kidney failure subsequent to the 12-month follow-up visit, which was unrelated to the device or the spinal fusion procedure. Fusion rate at 2 years for the tantalum device was very low as compared with the control arm (44% vs. 100%).

https://www.researchgate.net/public...pective_Randomized_Multicenter_Clinical_Study

Maybe now people can understand why Zimmer would be looking to Amedica's Si3n4 material. Si3n4 does what trabecular metal cannot do.


Porous silicon nitride spacers versus PEEK cages for anterior cervical discectomy and fusion: clinical and radiological results of a single-blinded randomized controlled trial
https://link.springer.com/article/10.1007/s00586-017-5079-6

Silicon Nitride (Si3N4) Implants: The Future of Dental Implantology?
http://www.joionline.org/doi/10.1563/aaid-joi-D-16-00146?code=aaid-premdev

Silicon nitride ceramic cages versus PEEK cages for anterior cervical discectomy with interbody fusion: first users’ experiences in a two center study
http://www.egms.de/static/en/meetings/dgch2016/16dgch266.shtml
 
https://www.researchgate.net/public...pective_Randomized_Multicenter_Clinical_Study

Maybe now people can understand why Zimmer would be looking to Amedica's Si3n4 material. Si3n4 does what trabecular metal cannot do.


Porous silicon nitride spacers versus PEEK cages for anterior cervical discectomy and fusion: clinical and radiological results of a single-blinded randomized controlled trial
https://link.springer.com/article/10.1007/s00586-017-5079-6

Silicon Nitride (Si3N4) Implants: The Future of Dental Implantology?
http://www.joionline.org/doi/10.1563/aaid-joi-D-16-00146?code=aaid-premdev

Silicon nitride ceramic cages versus PEEK cages for anterior cervical discectomy with interbody fusion: first users’ experiences in a two center study
http://www.egms.de/static/en/meetings/dgch2016/16dgch266.shtml

HO-LEE-SHIT. Go the fuck away with your stupidity. How desperate are you? Really? Please explain your desperation in the next post you make.
 
HO-LEE-SHIT. Go the fuck away with your stupidity. How desperate are you? Really? Please explain your desperation in the next post you make.

Dear Mr Pot, Kettle, Black:

Your response to someone making their case from the peer-reviewed literature sounds like a Christian Bale movie set rant. I hope your surgeons are more impressed than we are that you can syllabilize clearly when you curse. The next time you ask for someone to explain their desperation, consider ways to frame the question that aren't ironically soaked in your own desperation. Better yet, engage with counterpoints that don't cause regret for those who have invested sales training resources in you.

Sincerely,
Yippee Ki-Yay
 
Dear Mr Pot, Kettle, Black:

Your response to someone making their case from the peer-reviewed literature sounds like a Christian Bale movie set rant. I hope your surgeons are more impressed than we are that you can syllabilize clearly when you curse. The next time you ask for someone to explain their desperation, consider ways to frame the question that aren't ironically soaked in your own desperation. Better yet, engage with counterpoints that don't cause regret for those who have invested sales training resources in you.

Sincerely,
Yippee Ki-Yay

YOUR PRODUCT SUCKS. YOUR PAPERS SUCK. YOU SUCK. Why do you want to be bought so bad? Because YOUR DESPERATE and you know it's YOUR ONLY CHANCE. Keep posting nonsense and keep getting trolled. Welcome to the internet.
 


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