Recent Posts

Post thread…


Lee Ellen Hauser - Astellas
anonymous
Jun 19, 2025 at 07:55 PM
Tom tom - MannKind

  • More and more people will continue to leave this pit of a place. I just accepted an offer for a lot more money and a bonus double what I get now. I'm walking away with absolutely nothing in bonus. Worked my tail off and no prescriptions are getting through!. If anyone thinks that this ship will make it to the harbor, you better wake up.

anonymous
Jun 19, 2025 at 07:37 PM
Next Reorg - Novo Nordisk

  • anonymous said:
    You sound like a Lilly REP! It’s about GLP-1, close to the homology of native GLP1, Not primarily just weight loss. The Surpass-CVOT is set to underwhelm. Mounjaro has a homology to native GLP-1 to about 30-40%, while its GIP is 80%. It's GLP-1 activity is 1/5 of Ozempic's and at best a weak to modest agonist at the receptor site. Ozempic is the most potent GLP-1 ever created. Now we know that ASCVD reduction is more about GLP-1 than Weight loss. Tanzeum's CVOT trial yielded a weight loss of 1.5lbs and had a 22% reduction in 3-point mace. Lilly's CVOT trial is powered to include modest BMI's so weight loss will not be as significant. GIP has been associated with inflammation as well. What we will see is that Mounjaro will fail to achieve noninferiority vs. trulicity in a 4 point mace composite while showing noninferiority to a single component of the 4 point mace being Heart Failure. 4 point MACE was added as a security blanket just in case the overall composite was negative.
    Click to expand...
    A true disciple of Novo medical brainwashing. No one gives a shit about the about how homologous Semaglutide is but you. Novo must also employ Nostradamus since you all can see into the future and predict CVOT outcomes before data is even released. Keep on dreaming you dumb fucks!

anonymous
Jun 19, 2025 at 07:17 PM
Novocure - Medical Equipment/Device Sales-General Discussion

  • anonymous said:
    I had the unfortunáte encounter with JM during ASCO. I don’t frankly quite understand how she is a so-called leader. She is the most unimpressive person I have met in my 16 years in industry.
    Click to expand...
    She's an absolute train wreck JM to hire idiots and let go of the talent

anonymous
Jun 19, 2025 at 07:16 PM
Toxic Manager Alert - Esperion

  • anonymous said:
    I know of another manager who has lost a few since the beginning of this year. And LinkedIn says everyone else on their team but 1 is looking. Crazy times we’re in.
    Click to expand...
    Conversely, a lot of people think it’s a great time to come on board. The amount of equity options is a compelling reason to think longer term, easily can foresee a 5-10x over the next several years. It is apparent that many people here can’t sell very well, and that’s a fertile environment to step into as a true professional that can really make hay when much of the competition is weak. It is reassuring that management is apparently done with mediocrity, that bodes well for upgrading the field force.The only real concern with coming on board now is the looming potential for a buyout, but I’ve also been impressed with some of the potential suitors mentioned. I’ve also heard about acquiring a GLP-1 compound, very exciting and additive to the concept of lowering CVD burden. What’s not to like?

anonymous
Jun 19, 2025 at 07:14 PM
Top Bottom
Back
Post thread…