J&J opts out of licensing Genmab's Darzalex challenger after look at phase 1/2 data
Johnson & Johnson is dropping a partnership with Genmab centered around a CD38 monoclonal antibody, prompting the latter company to discontinue development of the program.
Sanofi scores with its subcutaneous version of Sarclisa as it tries to play catch up with J&J's Darzalex
Trailing Johnson & Johnson’s powerhouse Darzalex by roughly five years in its development timeline has made it challenging for Sanofi’s Sarclisa—the only other CD38 antibody on the market for multiple myeloma—to compete in the indication.
ASH: With survival win against J&J's Darzalex, GSK bolsters case for return of myeloma ADC Blenrep
GSK’s antibody-drug conjugate Blenrep has mounted a sizable patient survival benefit among certain multiple myeloma patients in a head-to-head comparison against Johnson & Johnson’s industry-leading Darzalex.
J&J angles Darzalex for first move into early-stage myeloma with trial win, FDA filing
After a positive phase 3 trial, Johnson & Johnson hopes its Darzalex could become the first treatment option for patients with smoldering multiple myeloma, an early-stage form of the blood disorder.
Top 40 Best-Selling Oncology Drugs in 2023 by 2022 Data
In the dynamic landscape of oncology therapeutics, understanding the trends and performances of leading drugs is crucial for stakeholders across the healthcare and life sciences sectors. The top 40 best-selling oncology drugs in 2023, informed by 2022 sales statistics, mark significant milestones in cancer treatment and research. This analysis not only highlights the financial success of these drugs but also sheds light on the therapeutic advancements and innovation driving patient outcomes in the oncology domain.
Genmab loses appeal in Darzalex royalties arbitration case against Johnson & Johnson
While sales for Johnson & Johnson’s Darzalex continue to boom—as the company reported in its quarterly earnings presentation on Tuesday—the pharma major got more good news about its blockbuster multiple myeloma treatment with a victory in an arbitration case.
ASH: J&J, Sanofi square off in newly diagnosed multiple myeloma
Another data face-off between the two anti-CD38 multiple myeloma drugs—Johnson & Johnson’s Darzalex and Sanofi’s Sarclisa—took place at the 65th American Society of Hematology meeting. Both regimens showed strong efficacy data in newly diagnosed patients, but only one result is considered practice-changing right now.
Focus On Genmab's Pipeline If Darzalex Arbitration with Janssen Goes Sideways
Genmab A/S decided to file a request to review the award dismissing its claims in the second arbitration arising under its license agreement with Johnson & Johnson's Janssen Biotech Inc for Darzalex (daratumumab).
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